Gene: USH1C
mRNA Accession: BC016057
Mutation:USH1C.txt
Chromosome: chr 11

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
+1188A>G
Sequence Walker   		t17578141c 17578179 -3 17578176 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
+1188A>G
Sequence Walker   		t17578141c 17578109 67 17578176 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
+1188A>G
Sequence Walker   		t17578141c 17578101 75 17578176 4.1 4.1 0.0 1.0 100 -1.2 -1.2 0.0
+1877C>T
Sequence Walker   		g17554790a 17554840 -239 17554601 3.0 3.0 0.0 1.0 100 -1.5 -1.5 0.0
+1877C>T
Sequence Walker   		g17554790a 17554770 -169 17554601 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
+381G>T
Sequence Walker   		c17591861a 17591880 -26 17591854 3.3 3.3 0.0 1.0 100 -1.4 -1.4 0.0
+381G>T
Sequence Walker   		c17591861a 17591854 0 17591854 10.9 10.9 0.0 1.0 100 0.9 0.9 0.0
+381G>T
Sequence Walker   		c17591861a 17591835 19 17591854 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
+381G>T
Sequence Walker   		c17591861a 17591829 25 17591854 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
+91C>T
Sequence Walker   		g17593969a 17593964 -9 17593955 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
+91C>T
Sequence Walker   		g17593969a 17593955 0 17593955 8.1 8.1 0.0 1.0 100 0.0 0.0 0.0
+91C>T
Sequence Walker   		g17593969a 17593951 4 17593955 2.6 2.6 0.0 1.0 100 -1.6 -1.6 0.0
+91C>T
Sequence Walker   		g17593969a 17593931 24 17593955 2.7 2.7 0.0 1.0 100 -1.6 -1.6 0.0
IVS1-41insCC
Sequence Walker   		i17594063,17594064gg 17594082 -58 17594024 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-41insCC
Sequence Walker   		i17594063,17594064gg 17594048 -24 17594024 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-41insCC
Sequence Walker   		i17594063,17594064gg 17594023 1 17594024 5.7 5.7 0.0 1.0 100 -0.7 -0.7 0.0
IVS1-45C>G
Sequence Walker   		g17594068c 17594116 -92 17594024 0.6 0.6 0.0 1.0 100 -2.3 -2.3 0.0
IVS1-45C>G
Sequence Walker   		g17594068c 17594082 -58 17594024 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-45C>G
Sequence Walker   		g17594068c 17594048 -24 17594024 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-45C>G
Sequence Walker   		g17594068c 17594023 1 17594024 5.7 5.7 0.0 1.0 100 -0.7 -0.7 0.0
IVS1-47G>T
Sequence Walker   		c17594070a 17594116 -92 17594024 0.6 0.6 0.0 1.0 100 -2.3 -2.3 0.0
IVS1-47G>T
Sequence Walker   		c17594070a 17594082 -58 17594024 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-47G>T
Sequence Walker   		c17594070a 17594065 -41 17594024 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-47G>T
Sequence Walker   		c17594070a 17594048 -24 17594024 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
IVS1-47G>T
Sequence Walker   		c17594070a 17594023 1 17594024 5.7 5.7 0.0 1.0 100 -0.7 -0.7 0.0
IVS13-45A>G
Sequence Walker   		t17578220c 17578179 -3 17578176 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
IVS17-113A>G
Sequence Walker   		t17559085c 17559131 -158 17558973 5.8 5.8 0.0 1.0 100 -0.7 -0.7 0.0
IVS17-113A>G
Sequence Walker   		t17559085c 17559072 -99 17558973 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
IVS2-16C>T
Sequence Walker   		g17592259a 17592298 -54 17592244 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS2-16C>T
Sequence Walker   		g17592259a 17592289 -45 17592244 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
IVS2-16C>T
Sequence Walker   		g17592259a 17592276 -32 17592244 7.4 7.4 0.0 1.0 100 -0.2 -0.2 0.0
IVS2-16C>T
Sequence Walker   		g17592259a 17592221 23 17592244 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0
IVS5+1G>A
Sequence Walker   		c17587923t 17587972 -49 17587923 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS5+1G>A
Sequence Walker   		c17587923t 17587930 -7 17587923 7.3 7.3 0.0 1.0 100 -0.2 -0.2 0.0
IVS5+1G>A
Sequence Walker   		c17587923t 17587919 4 17587923 4.0 4.0 0.0 1.0 100 -1.2 -1.2 0.0
IVS5+1G>A
Sequence Walker   		c17587923t 17587887 36 17587923 6.4 6.4 0.0 1.0 100 -0.5 -0.5 0.0
IVS6-45delC
Sequence Walker   		d17587786,17587786 17587822 -80 17587742 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
IVS6-45delC
Sequence Walker   		d17587786,17587786 17587814 -72 17587742 7.9 7.9 0.0 1.0 100 -0.0 -0.0 0.0
IVS6-45delC
Sequence Walker   		d17587786,17587786 17587797 -55 17587742 6.4 6.4 0.0 1.0 100 -0.5 -0.5 0.0
IVS7+61G>A
Sequence Walker   		c17587393t 17587435 18 17587453 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
IVS7+61G>A
Sequence Walker   		c17587393t 17587427 26 17587453 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS7+61G>A
Sequence Walker   		c17587393t 17587421 32 17587453 4.1 4.1 0.0 1.0 100 -1.2 -1.2 0.0
IVS7+61G>A
Sequence Walker   		c17587393t 17587404 49 17587453 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
IVS7+61G>A
Sequence Walker   		c17587393t 17587383 70 17587453 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
IVS7-27G>A
Sequence Walker   		c17587169t 17587180 -37 17587143 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS7-27G>A
Sequence Walker   		c17587169t 17587139 4 17587143 0.6 0.6 0.0 1.0 100 -2.3 -2.3 0.0
IVS9-66T>C
Sequence Walker   		a17584245g 17584295 -115 17584180 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0