All Mutations grouped

Gene:	MTM1
mRNA Accession:	U46024
Chromosome:	chr X
Sequence Walker

c.2T>G

Instruction: t147532041g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147532029	0	147532029	5.4	5.4	0.0	1.0	100	-0.7	-0.7	0.0
No Change	147532031	2	147532029	0.9	0.9	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147532038	9	147532029	5.0	5.0	0.0	1.0	100	-0.8	-0.8	0.0
No Change	147532084	55	147532029	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	147532026	-3	147532029	1.2	1.2	0.0	1.0	100	-2.1	-2.1	0.0
increased	147532039	10	147532029	-4.1	0.0	4.1	1.0	101.7	-3.7	-2.4	1.2

c.145G>T

Instruction: g147538027t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147538018	0	147538018	7.0	7.0	0.0	1.0	100	-0.4	-0.4	0.0
No Change	147538024	6	147538018	0.0	0.0	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147538062	44	147538018	1.8	1.8	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	147537998	-20	147538018	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	147538063	45	147538018	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0

c.205C>T

Instruction: c147538087t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147538062	-52	147538114	1.8	1.8	0.0	1.0	100	-1.6	-1.6	0.0
Increased	147538100	-14	147538114	5.0	5.4	0.4	1.3	134.9	-0.9	-0.8	0.1
Increased	147538103	-11	147538114	2.0	2.1	0.1	1.1	109.7	-1.5	-1.5	0.0
Sites found for donor
No Change	147538063	-51	147538114	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147538114	0	147538114	10.6	10.6	0.0	1.0	100	0.8	0.8	0.0

c.535C>T

Instruction: c147580711t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147580702	-2	147580704	6.2	6.2	0.0	1.0	100	-0.6	-0.6	0.0
No Change	147580704	0	147580704	16.5	16.5	0.0	1.0	100	1.7	1.7	0.0
No Change	147580705	1	147580704	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
Sites found for donor
No Change	147580665	-39	147580704	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0

c.557C>T

Instruction: c147580733t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147580704	0	147580704	16.5	16.5	0.0	1.0	100	1.7	1.7	0.0
No Change	147580705	1	147580704	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	147580782	78	147580704	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor

c.614C>T

Instruction: c147580790t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147580782	-73	147580855	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Increased	147580804	-51	147580855	5.8	6.2	0.4	1.3	130.0	-0.7	-0.6	0.1
No Change	147580835	-20	147580855	1.5	1.5	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	147580783	-72	147580855	1.9	1.9	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147580818	-37	147580855	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0

c.679G>A

Instruction: g147585119a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147585093	-25	147585118	4.6	4.6	0.0	1.0	100	-0.9	-0.9	0.0
Decreased	147585118	0	147585118	5.9	4.9	-1.0	-1.9	51.5	-0.6	-0.9	-0.2
Increased	147585140	22	147585118	1.9	2.5	0.7	1.6	159.2	-1.5	-1.4	0.1
No Change	147585168	50	147585118	2.2	2.2	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
No Change	147585152	34	147585118	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147585158	40	147585118	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
Decreased	147585119	1	147585118	2.0	-10.8	-12.8	-4.0	NA	-1.8	-5.7	-3.9

c.683T>C

Instruction: t147585123c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147585118	0	147585118	5.9	5.9	0.0	1.0	100	-0.6	-0.6	0.0
Decreased	147585140	22	147585118	1.9	1.6	-0.2	-1.2	84.6	-1.5	-1.6	-0.1
No Change	147585168	50	147585118	2.2	2.2	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
Decreased	147585119	1	147585118	2.0	2.0	-0.0	-1.0	97.9	-1.8	-1.8	-0.0
No Change	147585152	34	147585118	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147585158	40	147585118	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147585168	50	147585118	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

c.721C>T

Instruction: c147585161t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147585140	22	147585118	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
Increased	147585168	50	147585118	2.2	2.2	0.0	1.0	102.7	-1.5	-1.4	0.0
Sites found for donor
No Change	147585119	1	147585118	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147585152	34	147585118	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	147585158	40	147585118	3.1	3.1	-0.0	-1.0	98.0	-1.5	-1.5	-0.0
No Change	147585168	50	147585118	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0
No Change	147585183	65	147585118	4.8	4.8	0.0	1.0	100	-1.0	-1.0	0.0
No Change	147585189	71	147585118	1.2	1.2	0.0	1.0	100	-2.1	-2.1	0.0

c.836C>G

Instruction: c147585276g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	147585287	-21	147585308	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147585308	0	147585308	12.6	12.6	0.0	1.0	100	1.4	1.4	0.0

c.1132G>A

Instruction: g147597335a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147597330	74	147597256	3.8	3.8	0.0	1.0	100	-1.1	-1.1	0.0
increased	147597336	80	147597256	-6.7	1.5	8.2	2.8	283.4	-3.4	-1.6	1.8
Sites found for donor
No Change	147597303	47	147597256	3.3	3.3	0.0	1.0	100	-1.4	-1.4	0.0
Decreased	147597330	74	147597256	1.3	1.0	-0.4	-1.3	77.5	-2.0	-2.1	-0.1

c.1172T>C

Instruction: t147597375c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147597396	-68	147597464	2.8	2.7	-0.1	-1.0	96.1	-1.3	-1.3	-0.0
Sites found for donor
No Change	147597330	-134	147597464	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	147597409	-55	147597464	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	147597422	-42	147597464	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0

c.1190A>G

Instruction: a147597393g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	147597396	-68	147597464	2.8	2.9	0.1	1.1	109.6	-1.3	-1.3	0.0
Sites found for donor
No Change	147597409	-55	147597464	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	147597422	-42	147597464	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
increased	147597393	-71	147597464	-10.8	2.0	12.8	4.1	410.2	-5.7	-1.8	3.9

c.1204G>A

Instruction: g147597407a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147597396	-68	147597464	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
Sites found for donor
Increased	147597409	-55	147597464	1.1	3.4	2.3	4.9	489.0	-2.1	-1.4	0.7
No Change	147597422	-42	147597464	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0

c.1262G>A

Instruction: g147599101a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	147599099	0	147599099	4.8	4.8	0.0	1.0	103.1	-0.9	-0.9	0.0
Increased	147599106	7	147599099	2.7	2.9	0.2	1.1	111.8	-1.3	-1.3	0.0
Sites found for donor
No Change	147599107	8	147599099	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147599113	14	147599099	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0

c.85C>T

Instruction: c147535946t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147535924	0	147535924	9.0	9.0	0.0	1.0	100	0.0	0.0	0.0
No Change	147535934	10	147535924	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	147535979	55	147535924	9.3	9.3	0.0	1.0	100	0.1	0.1	0.0
Sites found for donor

c.109C>T

Instruction: c147535970t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	147535979	-19	147535998	9.3	9.9	0.6	1.5	149.8	0.1	0.2	0.1
Sites found for donor
No Change	147535998	0	147535998	9.4	9.4	0.0	1.0	100	0.4	0.4	0.0

c.142G>T

Instruction: g147538024t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147537996	-22	147538018	8.4	8.4	0.0	1.0	100	-0.1	-0.1	0.0
No Change	147538018	0	147538018	7.0	7.0	0.0	1.0	100	-0.4	-0.4	0.0
No Change	147538062	44	147538018	1.8	1.8	0.0	1.0	100	-1.6	-1.6	0.0
Decreased	147538024	6	147538018	0.0	-8.7	-8.7	-1.0	NA	-1.9	-3.8	-1.9
Sites found for donor
No Change	147537975	-43	147538018	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147537998	-20	147538018	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	147538063	45	147538018	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0

c.181G>T

Instruction: g147538063t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147538100	82	147538018	5.0	5.0	0.0	1.0	100	-0.9	-0.9	0.0
No Change	147538103	85	147538018	2.0	2.0	0.0	1.0	100	-1.5	-1.5	0.0
Decreased	147538062	44	147538018	1.8	-0.5	-2.2	-3.4	NA	-1.6	-2.0	-0.5
Sites found for donor
increased	147538058	40	147538018	-1.0	0.2	1.2	1.2	118.7	-2.7	-2.4	0.4
increased	147538062	44	147538018	-5.3	2.9	8.2	7.7	766.7	-4.0	-1.5	2.5

c.1261C>T

Instruction: c147599100t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147599099	0	147599099	4.8	4.5	-0.3	-1.2	80.9	-0.9	-1.0	-0.1
Increased	147599106	7	147599099	2.7	2.9	0.2	1.1	111.1	-1.3	-1.3	0.0
Sites found for donor
No Change	147599107	8	147599099	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147599113	14	147599099	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0
increased	147599099	0	147599099	-5.3	2.1	7.5	4.4	439.3	-4.1	-1.8	2.3

c.1420C>T

Instruction: c147599873t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147599868	-53	147599921	2.6	2.6	0.0	1.0	100	-1.4	-1.4	0.0
Decreased	147599895	-26	147599921	0.4	0.4	-0.0	-1.0	96.5	-1.8	-1.9	-0.0
Decreased	147599898	-23	147599921	0.1	0.1	-0.0	-1.0	98.4	-1.9	-1.9	-0.0
Sites found for donor
No Change	147599880	-41	147599921	1.5	1.5	0.0	1.0	100	-2.0	-2.0	0.0
No Change	147599898	-23	147599921	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147599921	0	147599921	11.8	11.8	0.0	1.0	100	1.2	1.2	0.0

c.1456C>T

Instruction: c147599909t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147599895	-26	147599921	0.4	0.4	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147599898	-23	147599921	0.1	0.1	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147599954	33	147599921	5.3	5.3	0.0	1.0	100	-0.8	-0.8	0.0
Sites found for donor
No Change	147599880	-41	147599921	1.5	1.5	0.0	1.0	100	-2.0	-2.0	0.0
No Change	147599898	-23	147599921	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147599921	0	147599921	11.8	11.8	0.0	1.0	100	1.2	1.2	0.0

c.63+2T>C

Instruction: t147532104c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147532084	-19	147532103	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Decreased	147532119	16	147532103	0.6	0.3	-0.2	-1.2	86.1	-1.8	-1.9	-0.0
No Change	147532140	37	147532103	2.1	2.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147532143	40	147532103	4.9	4.9	0.0	1.0	100	-0.9	-0.9	0.0
No Change	147532147	44	147532103	0.3	0.3	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147532151	48	147532103	1.0	1.0	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
Decreased	147532103	0	147532103	9.8	2.3	-7.5	-177.5	0.5	0.5	-1.7	-2.3
No Change	147532108	5	147532103	0.3	0.3	0.0	1.0	100	-2.3	-2.3	0.0

c.64-2A>G

Instruction: a147535923g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147535924	0	147535924	9.0	0.8	-8.2	-286.2	0.3	0.0	-1.8	-1.8
Increased	147535934	10	147535924	1.7	2.1	0.3	1.3	125.6	-1.6	-1.5	0.1
increased	147535923	-1	147535924	-4.4	3.2	7.6	9.0	896.5	-2.9	-1.2	1.7
Sites found for donor
No Change	147535876	-48	147535924	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	147535880	-44	147535924	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
No Change	147535886	-38	147535924	3.6	3.6	0.0	1.0	100	-1.4	-1.4	0.0

c.137-7T>G

Instruction: t147538012g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147537996	-22	147538018	8.4	8.4	0.0	1.0	100	-0.1	-0.1	0.0
Decreased	147538018	0	147538018	7.0	4.8	-2.2	-4.6	21.7	-0.4	-0.9	-0.5
No Change	147538062	44	147538018	1.8	1.8	0.0	1.0	100	-1.6	-1.6	0.0
Decreased	147538024	6	147538018	0.0	-1.9	-2.0	-1.0	NA	-1.9	-2.4	-0.4
Sites found for donor
No Change	147537975	-43	147538018	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147537998	-20	147538018	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
increased	147538012	-6	147538018	-6.5	1.3	7.8	2.5	246.0	-4.4	-2.0	2.4

c232-3C>A

Instruction: c147554022a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147554024	0	147554024	11.4	7.2	-4.2	-18.7	5.3	0.6	-0.4	-0.9
No Change	147554054	30	147554024	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
No Change	147554055	31	147554024	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	147554056	32	147554024	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0

c.232-2A>C

Instruction: a147554023c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147554024	0	147554024	11.4	4.0	-7.4	-171.7	0.5	0.6	-1.1	-1.6
No Change	147554054	30	147554024	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
No Change	147554055	31	147554024	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
increased	147554025	1	147554024	-3.1	1.2	4.2	2.2	223.9	-2.6	-1.7	0.9
Sites found for donor
No Change	147554056	32	147554024	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0

c.528+1G>A

Instruction: g147578463a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	147578415	-48	147578463	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
No Change	147578470	7	147578463	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147578488	25	147578463	7.9	7.9	0.0	1.0	100	-0.0	-0.0	0.0
No Change	147578492	29	147578463	2.3	2.3	0.0	1.0	100	-1.7	-1.7	0.0
Decreased	147578459	-4	147578463	1.5	-2.0	-3.5	-2.9	NA	-2.0	-3.0	-1.1
Decreased	147578463	0	147578463	10.6	-2.2	-12.8	-1568.3	NA	0.8	-3.1	-3.9

c.1261-10A>G

Instruction: a147599090g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	147599099	0	147599099	4.8	5.2	0.4	1.3	133.5	-0.9	-0.8	0.1
Increased	147599106	7	147599099	2.7	2.7	0.0	1.0	103.1	-1.3	-1.3	0.0
increased	147599090	-9	147599099	-6.1	1.5	7.6	2.8	278.4	-3.3	-1.6	1.7
Sites found for donor
No Change	147599107	8	147599099	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147599113	14	147599099	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0

c.1353+1G>A

Instruction: g147599193a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147599166	-27	147599193	3.8	3.8	0.0	1.0	100	-1.1	-1.1	0.0
Sites found for donor
No Change	147599170	-23	147599193	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	147599172	-21	147599193	0.6	0.6	0.0	1.0	100	-2.3	-2.3	0.0
Decreased	147599193	0	147599193	11.5	-1.3	-12.8	-2922.7	NA	1.1	-2.8	-3.9

c.1354-1G>A

Instruction: g147599806a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147599801	-5	147599806	1.5	1.5	0.0	1.0	100	-1.6	-1.6	0.0
Decreased	147599806	0	147599806	8.5	0.9	-7.6	-191.1	0.5	-0.1	-1.7	-1.7
Decreased	147599814	8	147599806	2.0	1.7	-0.3	-1.2	81.2	-1.5	-1.6	-0.1
Decreased	147599816	10	147599806	10.7	10.2	-0.4	-1.4	73.8	0.4	0.3	-0.1
Sites found for donor

c.1467+1G>A

Instruction: g147599921a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147599895	-26	147599921	0.4	0.4	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147599898	-23	147599921	0.1	0.1	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147599954	33	147599921	5.3	5.3	0.0	1.0	100	-0.8	-0.8	0.0
Sites found for donor
No Change	147599880	-41	147599921	1.5	1.5	0.0	1.0	100	-2.0	-2.0	0.0
No Change	147599898	-23	147599921	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	147599967	46	147599921	6.2	6.2	0.0	1.0	100	-0.6	-0.6	0.0
Decreased	147599921	0	147599921	11.8	-1.0	-12.8	-3573.6	NA	1.2	-2.7	-3.9

c.106delC

Instruction: d147535967,147535967 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147535979	-19	147535998	9.3	9.0	-0.3	-1.2	80.2	0.1	0.0	-0.1
Sites found for donor
No Change	147535998	0	147535998	9.4	9.4	0.0	1.0	100	0.4	0.4	0.0

c.141-142insG

Instruction: i147538024,147538025g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147537996	-22	147538018	8.4	8.4	0.0	1.0	100	-0.1	-0.1	0.0
No Change	147538018	0	147538018	7.0	7.0	0.0	1.0	100	-0.4	-0.4	0.0
Increased	147538024	6	147538018	0.0	1.0	1.0	1.9	193.9	-1.9	-1.7	0.2
No Change	147538062	44	147538018	1.8	1.8	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	147537975	-43	147538018	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147537998	-20	147538018	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	147538063	45	147538018	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0
increased	147538024	6	147538018	-4.8	0.8	5.5	1.7	171.9	-3.9	-2.2	1.7

c.465delT

Instruction: d147578399,147578399 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147578377	-1	147578378	0.2	0.2	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147578378	0	147578378	11.9	11.9	0.0	1.0	100	0.7	0.7	0.0
No Change	147578382	4	147578378	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
Decreased	147578397	19	147578378	0.6	0.1	-0.5	-1.4	70.0	-1.8	-1.9	-0.1
Decreased	147578403	25	147578378	2.6	0.6	-2.0	-3.9	25.6	-1.4	-1.8	-0.4
increased	147578400	22	147578378	-4.1	5.4	9.5	41.7	4173.0	-2.8	-0.8	2.1
Sites found for donor
No Change	147578415	37	147578378	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0

c.469delG

Instruction: d147578403,147578403 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147578377	-1	147578378	0.2	0.2	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147578378	0	147578378	11.9	11.9	0.0	1.0	100	0.7	0.7	0.0
No Change	147578382	4	147578378	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
No Change	147578397	19	147578378	0.6	0.6	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	147578403	25	147578378	2.6	-5.0	-7.6	-6.1	NA	-1.4	-3.0	-1.7
Sites found for donor
No Change	147578415	37	147578378	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0

c.593-594insA

Instruction: i147580770,147580771a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147580804	100	147580704	5.8	5.8	0.0	1.0	100	-0.7	-0.7	0.0
Decreased	147580782	78	147580704	1.6	-10.9	-12.5	-3.1	NA	-1.6	-4.3	-2.7
Sites found for donor
No Change	147580783	79	147580704	1.9	1.9	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147580818	114	147580704	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0

c.445-1insGAAA

Instruction: i147532040,147532041gaaa ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147532029	0	147532029	5.4	5.4	0.0	1.0	100	-0.7	-0.7	0.0
No Change	147532031	2	147532029	0.9	0.9	0.0	1.0	100	-1.8	-1.8	0.0
No Change	147532038	9	147532029	5.0	5.0	0.0	1.0	100	-0.8	-0.8	0.0
No Change	147532084	55	147532029	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	147532026	-3	147532029	1.2	1.2	0.0	1.0	100	-2.1	-2.1	0.0

c.601delT

Instruction: d147580777,147580777 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	147580782	78	147580704	1.6	0.5	-1.1	-2.2	45.2	-1.6	-1.8	-0.2
No Change	147580804	100	147580704	5.8	5.8	0.0	1.0	100	-0.7	-0.7	0.0
Sites found for donor
No Change	147580783	79	147580704	1.9	1.9	0.0	1.0	100	-1.9	-1.9	0.0
No Change	147580818	114	147580704	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0

c.969insA

Instruction: i147589253,147589254a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147589281	-57	147589338	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	147589303	-35	147589338	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
No Change	147589254	-84	147589338	4.8	4.8	0.0	1.0	100	-1.0	-1.0	0.0
No Change	147589278	-60	147589338	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0

c.1015insT

Instruction: i147589299,147589300t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	147589281	-57