All Mutations grouped

Gene:	DTD
mRNA Accession:	U14528
Chromosome:	chr 5
Sequence Walker

IVS1+2T>C

Instruction: t149341074c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149341058	-15	149341073	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	149341072	-1	149341073	3.0	2.1	-0.9	-1.9	52.2	-1.3	-1.5	-0.2
No Change	149341105	32	149341073	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	149341034	-39	149341073	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
No Change	149341046	-27	149341073	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
Decreased	149341073	0	149341073	11.3	3.8	-7.5	-177.5	0.5	1.0	-1.3	-2.3
No Change	149341095	22	149341073	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149341110	37	149341073	3.7	3.7	0.0	1.0	100	-1.3	-1.3	0.0
No Change	149341118	45	149341073	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0

74C>G

Instruction: c149340447g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	149340480	134	149340346	1.5	1.5	0.0	1.0	100	-2.0	-2.0	0.0
increased	149340447	101	149340346	-5.5	4.3	9.8	20.1	2013.8	-4.1	-1.1	3.0

82G>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 82G>T the old base at 149340455 is NOT g! It is c.

256A>C

Instruction: a149340629c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149340656	310	149340346	1.1	1.1	0.0	1.0	100	-1.7	-1.7	0.0
No Change	149340661	315	149340346	0.1	0.1	0.0	1.0	100	-1.9	-1.9	0.0
No Change	149340664	318	149340346	12.1	12.1	0.0	1.0	100	0.7	0.7	0.0
Sites found for donor

282delC

Instruction: d149340655,149340655 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	149340664	318	149340346	12.1	11.4	-0.7	-1.7	59.8	0.7	0.5	-0.2
Decreased	149340656	310	149340346	1.1	-8.4	-9.5	-2.2	NA	-1.7	-3.8	-2.1
Decreased	149340661	315	149340346	0.1	-6.4	-6.5	-1.1	NA	-1.9	-3.3	-1.4
Sites found for donor

359G>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 359G>T the old base at 149340732 is NOT g! It is t.

418delT

Instruction: d149340791,149340791 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149340766	-307	149341073	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
No Change	149340769	-304	149341073	4.3	4.3	0.0	1.0	100	-1.0	-1.0	0.0
No Change	149340773	-300	149341073	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
No Change	149340779	-294	149341073	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Increased	149340816	-257	149341073	7.8	8.6	0.9	1.9	185.5	-0.2	-0.0	0.2
No Change	149340819	-254	149341073	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
No Change	149340835	-238	149341073	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149340836	-237	149341073	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
Sites found for donor
No Change	149340837	-236	149341073	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
Decreased	149340792	-281	149341073	2.6	-17.6	-20.2	-5.9	NA	-1.7	-7.8	-6.1

422T>C

Instruction: t149340795c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149340766	-307	149341073	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
No Change	149340769	-304	149341073	4.3	4.3	0.0	1.0	100	-1.0	-1.0	0.0
No Change	149340773	-300	149341073	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
No Change	149340779	-294	149341073	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	149340816	-257	149341073	7.8	7.7	-0.1	-1.0	96.1	-0.2	-0.3	-0.0
Increased	149340819	-254	149341073	0.9	1.0	0.1	1.1	108.2	-1.7	-1.7	0.0
No Change	149340835	-238	149341073	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149340836	-237	149341073	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149340846	-227	149341073	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
Increased	149340792	-281	149341073	2.6	2.6	0.0	1.0	102.0	-1.7	-1.6	0.0
No Change	149340837	-236	149341073	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0

430C>A

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 430C>A the old base at 149340803 is NOT c! It is t.

476delT

Instruction: d149340849,149340849 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149340835	-238	149341073	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149340836	-237	149341073	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149340846	-227	149341073	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	149340872	-201	149341073	0.6	0.1	-0.5	-1.4	71.4	-1.8	-1.9	-0.1
Decreased	149340850	-223	149341073	0.3	-9.6	-9.9	-1.2	NA	-1.9	-4.0	-2.2
increased	149340860	-213	149341073	-1.8	0.1	1.9	1.0	104.3	-2.3	-1.9	0.4
Sites found for donor
No Change	149340837	-236	149341073	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	149340857	-216	149341073	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	149340891	-182	149341073	6.8	6.8	0.0	1.0	100	-0.4	-0.4	0.0

523G>A

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 523G>A the old base at 149340896 is NOT g! It is a.

558C>T

Instruction: c149340931t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	149340956	-117	149341073	7.5	7.5	-0.0	-1.0	98.4	-0.3	-0.3	-0.0
Sites found for donor
No Change	149340891	-182	149341073	6.8	6.8	0.0	1.0	100	-0.4	-0.4	0.0

IVS2+1G>C

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. IVS2+1G>C the old base at 149345120 is NOT g! It is a.

731-737delGATGGGC

Instruction: d149342277,149342283 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	149342287	-726	149343013	2.6	1.1	-1.4	-2.7	36.6	-1.4	-1.7	-0.3
Increased	149342298	-715	149343013	3.2	3.9	0.7	1.6	163.9	-1.2	-1.1	0.2
increased	149342294	-719	149343013	-1.0	0.9	1.9	1.8	184.6	-2.2	-1.7	0.4
increased	149342297	-716	149343013	-0.7	1.5	2.3	2.9	290.1	-2.1	-1.6	0.5
increased	149342301	-712	149343013	-0.2	0.9	1.1	1.9	185.7	-2.0	-1.7	0.2
Sites found for donor
No Change	149342243	-770	149343013	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0
Increased	149342284	-729	149343013	2.6	4.0	1.3	2.5	252.9	-1.6	-1.2	0.4
Decreased	149342280	-733	149343013	1.2	-22.6	-23.7	-2.3	NA	-2.1	-9.3	-7.2

791G>A

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 791G>A the old base at 149343105 is NOT g! It is t.

803G>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 803G>T the old base at 149343117 is NOT g! It is a.

862C>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 862C>T the old base at 149343176 is NOT c! It is a.

933-934delCT

Instruction: d149342080,149342081 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149342052	-961	149343013	3.7	3.7	0.0	1.0	100	-1.1	-1.1	0.0
Sites found for donor
No Change	149342045	-968	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149342057	-956	149343013	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	149342060	-953	149343013	0.0	0.0	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149342066	-947	149343013	2.5	2.5	0.0	1.0	100	-1.7	-1.7	0.0
No Change	149342070	-943	149343013	2.1	2.1	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	149342079	-934	149343013	5.4	5.3	-0.1	-1.0	96.0	-0.8	-0.8	-0.0
No Change	149342112	-901	149343013	6.9	6.9	0.0	1.0	100	-0.3	-0.3	0.0
Decreased	149342081	-932	149343013	0.8	-7.5	-8.3	-1.8	NA	-2.2	-4.7	-2.5

1045-1047delGTT

Instruction: d149341967,149341969 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149341962	-1051	149343013	8.5	8.5	0.0	1.0	100	-0.1	-0.1	0.0
No Change	149341997	-1016	149343013	6.0	6.0	0.0	1.0	100	-0.6	-0.6	0.0
Sites found for donor
Decreased	149341965	-1048	149343013	1.8	-6.2	-8.0	-3.6	NA	-1.9	-4.3	-2.4

1184C>T

Instruction: c149343498t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	149343506	493	149343013	0.8	1.2	0.3	1.2	124.6	-1.8	-1.7	0.1
Increased	149343518	505	149343013	0.7	0.9	0.2	1.1	111.8	-1.8	-1.8	0.0
Decreased	149343520	507	149343013	2.5	2.5	-0.0	-1.0	96.5	-1.4	-1.4	-0.0
No Change	149343532	519	149343013	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	149343456	443	149343013	2.6	2.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	149343458	445	149343013	0.5	0.5	0.0	1.0	100	-2.3	-2.3	0.0
No Change	149343464	451	149343013	0.5	0.5	0.0	1.0	100	-2.3	-2.3	0.0
No Change	149343540	527	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0

1221delA

Instruction: d149343535,149343535 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149343506	493	149343013	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
No Change	149343518	505	149343013	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
No Change	149343520	507	149343013	2.5	2.5	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149343532	519	149343013	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	149343540	527	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149343568	555	149343013	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0

1269-1272delAAAC

Instruction: d149341742,149341745 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	149341767	-1246	149343013	1.1	1.3	0.2	1.2	117.8	-1.7	-1.7	0.1
Decreased	149341770	-1243	149343013	0.4	0.1	-0.3	-1.2	80.0	-1.8	-1.9	-0.1
Sites found for donor
No Change	149341702	-1311	149343013	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0

1300A>G

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 1300A>G the old base at 149343614 is NOT a! It is t.

1388A>C

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 1388A>C the old base at 149343702 is NOT a! It is t.

1421delT

Instruction: d149343735,149343735 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149343712	699	149343013	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
No Change	149343722	709	149343013	8.1	8.1	0.0	1.0	100	-0.2	-0.2	0.0
No Change	149343728	715	149343013	4.8	4.8	0.0	1.0	100	-0.9	-0.9	0.0
Decreased	149343751	738	149343013	5.5	5.0	-0.4	-1.3	74.3	-0.7	-0.8	-0.1
Decreased	149343752	739	149343013	1.9	1.5	-0.3	-1.3	79.3	-1.5	-1.6	-0.1
Decreased	149343753	740	149343013	1.2	0.5	-0.7	-1.6	60.9	-1.7	-1.8	-0.2
Decreased	149343756	743	149343013	2.0	1.9	-0.1	-1.1	91.0	-1.5	-1.5	-0.0
Sites found for donor
No Change	149343684	671	149343013	5.4	5.4	0.0	1.0	100	-0.8	-0.8	0.0
No Change	149343689	676	149343013	4.3	4.3	0.0	1.0	100	-1.1	-1.1	0.0
No Change	149343722	709	149343013	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
No Change	149343756	743	149343013	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149343765	752	149343013	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149343767	754	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149343779	766	149343013	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0

1475T>C

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 1475T>C the old base at 149343789 is NOT t! It is g.

1478G>A

Instruction: g149343792a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	149343810	797	149343013	0.7	0.5	-0.2	-1.2	86.5	-1.8	-1.8	-0.0
Sites found for donor
No Change	149343756	743	149343013	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149343765	752	149343013	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149343767	754	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149343779	766	149343013	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0
Increased	149343790	777	149343013	0.3	0.7	0.4	1.3	131.9	-2.3	-2.2	0.1
No Change	149343801	788	149343013	0.9	0.9	0.0	1.0	100	-2.2	-2.2	0.0
No Change	149343826	813	149343013	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0

1501C>T

Instruction: c149343815t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149343810	797	149343013	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	149343765	752	149343013	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149343767	754	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
No Change	149343779	766	149343013	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	149343790	777	149343013	0.3	0.3	0.0	1.0	100	-2.3	-2.3	0.0
No Change	149343801	788	149343013	0.9	0.9	0.0	1.0	100	-2.2	-2.2	0.0
No Change	149343826	813	149343013	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0
No Change	149343859	846	149343013	2.5	2.5	0.0	1.0	100	-1.7	-1.7	0.0

1677delG

Instruction: d149343991,149343991 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149344023	1010	149343013	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	149344024	1011	149343013	3.5	3.5	0.0	1.0	100	-1.2	-1.2	0.0
No Change	149344033	1020	149343013	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	149343983	970	149343013	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	149343998	985	149343013	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0

1748C>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 1748C>T the old base at 149344062 is NOT c! It is t.

1751delA

Instruction: d149344065,149344065 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	149344081	1068	149343013	0.5	0.3	-0.2	-1.2	86.5	-1.8	-1.9	-0.0
Increased	149344083	1070	149343013	1.4	1.8	0.4	1.3	130.8	-1.6	-1.5	0.1
Decreased	149344067	1054	149343013	5.3	-12.7	-18.0	-39.7	NA	-0.8	-4.7	-3.9
Decreased	149344078	1065	149343013	0.3	-11.3	-11.5	-1.2	NA	-1.9	-4.4	-2.5
Sites found for donor

1984T>A

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 1984T>A the old base at 149344298 is NOT t! It is g.

2003delT

Instruction: d149344317,149344317 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149344292	-828	149345120	1.8	1.8	0.0	1.0	100	-1.5	-1.5	0.0
No Change	149344298	-822	149345120	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
No Change	149344301	-819	149345120	3.7	3.7	0.0	1.0	100	-1.1	-1.1	0.0
No Change	149344369	-751	149345120	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor

2010delA

Instruction: d149344324,149344324 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149344298	-822	149345120	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
No Change	149344301	-819	149345120	3.7	3.7	0.0	1.0	100	-1.1	-1.1	0.0
No Change	149344369	-751	149345120	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor

2021A>C

Instruction: a149344335c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	149344369	-751	149345120	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
increased	149344354	-766	149345120	-0.5	0.1	0.6	1.1	106.7	-2.0	-1.9	0.1
Sites found for donor
No Change	149344382	-738	149345120	6.0	6.0	0.0	1.0	100	-0.6	-0.6	0.0

2060G>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 2060G>T the old base at 149344374 is NOT g! It is a.

2092A>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 2092A>T the old base at 149344406 is NOT a! It is g.

2171C>T

Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Unprocessed due to the following error. 2171C>T the old base at 149344485 is NOT c! It is a.