All Mutations grouped

Gene:	DHCR7
mRNA Accession:	AF034544
Chromosome:	chr 11
Sequence Walker

111G>A

Instruction: c71377947t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71377960	0	71377960	8.8	8.8	0.0	1.0	100	-0.0	-0.0	0.0
No Change	71377956	4	71377960	0.0	0.0	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71377900	60	71377960	1.2	1.2	0.0	1.0	100	-1.7	-1.7	0.0
No Change	71377898	62	71377960	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71377987	-27	71377960	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
No Change	71377985	-25	71377960	3.0	3.0	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71377959	1	71377960	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
No Change	71377955	5	71377960	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71377937	23	71377960	1.7	1.7	0.0	1.0	100	-1.9	-1.9	0.0

452G>A

Instruction: c71375145t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375116	69	71375185	1.8	1.8	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71375097	88	71375185	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	71375179	6	71375185	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	71375171	14	71375185	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0

682insC

Instruction: i71372771,71372772g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	71372816	12	71372828	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	71372765	63	71372828	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372761	67	71372828	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	70	71372828	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

762insT

Instruction: i71372691,71372692a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	71372685	-63	71372622	8.1	9.7	1.6	3.0	295.5	-0.2	0.2	0.3
Increased	71372680	-58	71372622	1.7	2.3	0.6	1.5	148.5	-1.6	-1.4	0.1
Decreased	71372677	-55	71372622	0.8	0.7	-0.1	-1.1	91.7	-1.8	-1.8	-0.0
Sites found for donor
No Change	71372658	-36	71372622	3.7	3.7	0.0	1.0	100	-1.3	-1.3	0.0

IVS8-1G>C

Instruction: c71369584g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71369592	-8	71369584	0.1	0.1	0.0	1.0	100	-1.9	-1.9	0.0
Decreased	71369584	0	71369584	13.5	6.2	-7.3	-156.4	0.6	1.0	-0.6	-1.6
Increased	71369583	1	71369584	1.4	2.1	0.7	1.7	166.6	-1.6	-1.5	0.2
No Change	71369554	30	71369584	4.3	4.3	0.0	1.0	100	-1.0	-1.0	0.0
No Change	71369539	45	71369584	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
increased	71369582	2	71369584	-4.0	2.0	6.0	3.9	388.0	-2.8	-1.5	1.3
Sites found for donor
Increased	71369582	2	71369584	2.4	2.7	0.3	1.2	120.0	-1.7	-1.6	0.1
No Change	71369571	13	71369584	0.4	0.4	0.0	1.0	100	-2.3	-2.3	0.0

151C>T

Instruction: g71377907a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	71377900	60	71377960	1.2	1.2	0.0	1.0	102.7	-1.7	-1.7	0.0
Increased	71377898	62	71377960	0.8	1.4	0.6	1.5	149.8	-1.8	-1.6	0.1
No Change	71377869	91	71377960	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71377864	96	71377960	2.2	2.2	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
No Change	71377955	5	71377960	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71377937	23	71377960	1.7	1.7	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71377876	84	71377960	1.5	1.5	0.0	1.0	100	-2.0	-2.0	0.0

278C>T

Instruction: g71377780a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71377737	-1	71377736	9.6	9.6	0.0	1.0	100	0.2	0.2	0.0
No Change	71377732	4	71377736	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71377729	7	71377736	1.1	1.1	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
No Change	71377776	-40	71377736	2.1	2.1	0.0	1.0	100	-1.8	-1.8	0.0
No Change	71377752	-16	71377736	4.1	4.1	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71377736	0	71377736	6.5	6.5	0.0	1.0	100	-0.5	-0.5	0.0

296T>C

Instruction: a71377762g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	71377737	-1	71377736	9.6	9.6	0.0	1.0	101.5	0.2	0.2	0.0
No Change	71377732	4	71377736	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71377729	7	71377736	1.1	1.1	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
No Change	71377776	-40	71377736	2.1	2.1	0.0	1.0	100	-1.8	-1.8	0.0
No Change	71377752	-16	71377736	4.1	4.1	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71377736	0	71377736	6.5	6.5	0.0	1.0	100	-0.5	-0.5	0.0
No Change	71377715	21	71377736	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0

321G>C

Instruction: c71377737g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	71377737	-1	71377736	9.6	2.3	-7.3	-156.4	0.6	0.2	-1.4	-1.6
Increased	71377732	4	71377736	1.4	4.1	2.7	6.3	628.1	-1.6	-1.0	0.6
Increased	71377729	7	71377736	1.1	2.7	1.6	3.0	303.6	-1.7	-1.4	0.4
Sites found for donor
No Change	71377776	-40	71377736	2.1	2.1	0.0	1.0	100	-1.8	-1.8	0.0
No Change	71377752	-16	71377736	4.1	4.1	0.0	1.0	100	-1.2	-1.2	0.0
Decreased	71377736	0	71377736	6.5	2.5	-4.0	-16.5	6.0	-0.5	-1.7	-1.2
No Change	71377715	21	71377736	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71377700	36	71377736	8.5	8.5	0.0	1.0	100	0.2	0.2	0.0

326T>C

Instruction: a71376093g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71376098	0	71376098	6.7	6.7	0.0	1.0	100	-0.5	-0.5	0.0
No Change	71376066	32	71376098	0.2	0.2	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71376060	38	71376098	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71376059	39	71376098	3.3	3.3	0.0	1.0	100	-1.2	-1.2	0.0
Decreased	71376084	14	71376098	0.0	-0.6	-0.6	-1.0	NA	-1.9	-2.1	-0.1
Sites found for donor
No Change	71376141	-43	71376098	3.4	3.4	0.0	1.0	100	-1.4	-1.4	0.0
No Change	71376130	-32	71376098	1.5	1.5	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71376123	-25	71376098	3.5	3.5	0.0	1.0	100	-1.4	-1.4	0.0
No Change	71376108	-10	71376098	3.3	3.3	0.0	1.0	100	-1.4	-1.4	0.0
Decreased	71376097	1	71376098	5.1	5.1	-0.0	-1.0	97.9	-0.9	-0.9	-0.0

356A>T

Instruction: t71376063a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71376084	14	71376098	0.0	0.0	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71376066	32	71376098	0.2	0.2	0.0	1.0	100	-1.9	-1.9	0.0
Increased	71376060	38	71376098	1.7	1.8	0.1	1.0	104.3	-1.6	-1.6	0.0
Increased	71376059	39	71376098	3.3	6.2	2.8	7.2	719.6	-1.2	-0.6	0.6
Increased	71376040	58	71376098	4.6	5.3	0.6	1.6	155.3	-0.9	-0.8	0.1
Sites found for donor
No Change	71376108	-10	71376098	3.3	3.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	71376097	1	71376098	5.1	5.1	0.0	1.0	100	-0.9	-0.9	0.0
No Change	71376043	55	71376098	3.3	3.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	71376028	70	71376098	1.2	1.2	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71376019	79	71376098	0.9	0.9	0.0	1.0	100	-2.1	-2.1	0.0

440G>A

Instruction: c71375157t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375185	0	71375185	11.8	11.8	0.0	1.0	100	0.6	0.6	0.0
No Change	71375116	69	71375185	1.8	1.8	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
No Change	71375179	6	71375185	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	71375171	14	71375185	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0

443T>G

Instruction: a71375154c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375116	69	71375185	1.8	1.8	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
No Change	71375179	6	71375185	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	71375171	14	71375185	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
increased	71375153	32	71375185	-1.7	1.6	3.3	3.0	304.5	-3.0	-1.9	1.0

461C>T

Instruction: g71375136a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	71375116	69	71375185	1.8	2.0	0.2	1.1	111.8	-1.5	-1.5	0.0
No Change	71375097	88	71375185	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71375085	100	71375185	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71375179	6	71375185	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	71375171	14	71375185	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0

461C>G

Instruction: g71375136c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	71375116	69	71375185	1.8	0.8	-1.0	-2.0	49.2	-1.5	-1.8	-0.2
No Change	71375097	88	71375185	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71375085	100	71375185	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
increased	71375136	49	71375185	-3.1	4.2	7.3	18.0	1800.0	-2.6	-1.0	1.6
Sites found for donor
No Change	71375179	6	71375185	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	71375171	14	71375185	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0

470T>C

Instruction: a71375127g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	71375116	69	71375185	1.8	1.3	-0.5	-1.5	68.3	-1.5	-1.7	-0.1
No Change	71375097	88	71375185	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71375085	100	71375185	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71375171	14	71375185	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0

502T>A

Instruction: a71375095t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375116	69	71375185	1.8	1.8	0.0	1.0	100	-1.5	-1.5	0.0
Decreased	71375097	88	71375185	1.6	1.1	-0.5	-1.4	72.2	-1.6	-1.7	-0.1
Decreased	71375085	100	71375185	0.7	-2.2	-2.8	-1.6	NA	-1.8	-2.4	-0.6
Sites found for donor
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71375051	134	71375185	4.4	4.4	0.0	1.0	100	-1.1	-1.1	0.0

506C>T

Instruction: g71375091a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375116	69	71375185	1.8	1.8	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71375097	88	71375185	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Increased	71375085	100	71375185	0.7	0.8	0.2	1.1	111.1	-1.8	-1.8	0.0
increased	71375082	103	71375185	-0.4	0.1	0.6	1.1	110.5	-2.0	-1.9	0.1
Sites found for donor
No Change	71375123	62	71375185	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71375051	134	71375185	4.4	4.4	0.0	1.0	100	-1.1	-1.1	0.0

523G>C

Instruction: c71375074g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375097	-127	71374970	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71375085	-115	71374970	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
increased	71375072	-102	71374970	-5.1	0.8	6.0	1.8	179.3	-3.1	-1.8	1.3
increased	71375070	-100	71374970	-1.6	0.9	2.5	1.9	187.9	-2.3	-1.7	0.6
increased	71375067	-97	71374970	-1.0	0.9	1.9	1.9	186.8	-2.2	-1.7	0.4
Sites found for donor
No Change	71375123	-153	71374970	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71375051	-81	71374970	4.4	4.4	0.0	1.0	100	-1.1	-1.1	0.0

529T>C

Instruction: a71375068g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375097	-127	71374970	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71375085	-115	71374970	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71375051	-81	71374970	4.4	4.4	0.0	1.0	100	-1.1	-1.1	0.0

533T>A

Instruction: a71375064t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375085	-115	71374970	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71375051	-81	71374970	4.4	4.4	0.0	1.0	100	-1.1	-1.1	0.0

536C>T

Instruction: g71375061a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375085	-115	71374970	0.7	0.7	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71375051	-81	71374970	4.4	4.4	0.0	1.0	100	-1.1	-1.1	0.0

546G>C

Instruction: c71375051g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71375003	-33	71374970	2.6	2.6	0.0	1.0	100	-1.4	-1.4	0.0
Sites found for donor
No Change	71375008	-38	71374970	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
Decreased	71375051	-81	71374970	4.4	-5.5	-9.8	-20.4	NA	-1.1	-4.1	-3.0

724C>T

Instruction: g71372730a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71372685	143	71372828	8.1	8.1	0.0	1.0	100	-0.2	-0.2	0.0
No Change	71372680	148	71372828	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	71372765	63	71372828	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372761	67	71372828	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	70	71372828	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

725G>A

Instruction: c71372729t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71372685	143	71372828	8.1	8.1	0.0	1.0	100	-0.2	-0.2	0.0
No Change	71372680	148	71372828	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71372677	151	71372828	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71372765	63	71372828	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372761	67	71372828	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	70	71372828	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

728C>G

Instruction: g71372726c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71372685	143	71372828	8.1	8.1	0.0	1.0	100	-0.2	-0.2	0.0
No Change	71372680	148	71372828	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71372677	151	71372828	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71372765	63	71372828	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372761	67	71372828	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	70	71372828	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

730G>A

Instruction: c71372724t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71372685	-63	71372622	8.1	8.1	0.0	1.0	100	-0.2	-0.2	0.0
No Change	71372680	-58	71372622	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71372677	-55	71372622	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
increased	71372723	-101	71372622	-4.9	3.2	8.2	9.5	949.8	-3.0	-1.2	1.8
Sites found for donor
No Change	71372765	-143	71372622	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372761	-139	71372622	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	-136	71372622	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

740C>T

Instruction: g71372714a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71372685	-63	71372622	8.1	8.1	0.0	1.0	100	-0.2	-0.2	0.0
No Change	71372680	-58	71372622	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71372677	-55	71372622	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71372765	-143	71372622	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372761	-139	71372622	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	-136	71372622	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

744G>T

Instruction: c71372710a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	71372685	-63	71372622	8.1	9.0	0.9	1.9	185.5	-0.2	0.0	0.2
No Change	71372680	-58	71372622	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71372677	-55	71372622	0.8	0.8	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
No Change	71372761	-139	71372622	1.1	1.1	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71372758	-136	71372622	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

808A>G

Instruction: t71372646c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	71372623	-1	71372622	6.6	6.2	-0.3	-1.2	80.5	-0.5	-0.6	-0.1
Sites found for donor
No Change	71372658	-36	71372622	3.7	3.7	0.0	1.0	100	-1.3	-1.3	0.0
No Change	71372637	-15	71372622	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	71372622	0	71372622	5.7	5.7	0.0	1.0	100	-0.7	-0.7	0.0
No Change	71372606	16	71372622	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71372600	22	71372622	4.6	4.6	0.0	1.0	100	-1.0	-1.0	0.0

841G>A

Instruction: c71371678t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71371688	0	71371688	9.3	9.3	0.0	1.0	100	0.1	0.1	0.0
Sites found for donor
No Change	71371726	-38	71371688	0.3	0.3	0.0	1.0	100	-2.3	-2.3	0.0
No Change	71371715	-27	71371688	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71371712	-24	71371688	3.6	3.6	0.0	1.0	100	-1.3	-1.3	0.0
No Change	71371649	39	71371688	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
Decreased	71371678	10	71371688	3.2	-9.6	-12.8	-9.0	NA	-1.5	-5.4	-3.9

852C>A

Instruction: g71371667t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71371688	0	71371688	9.3	9.3	0.0	1.0	100	0.1	0.1	0.0
increased	71371657	31	71371688	-6.2	1.2	7.4	2.3	229.9	-3.3	-1.7	1.6
Sites found for donor
No Change	71371715	-27	71371688	1.0	1.0	0.0	1.0	100	-2.1	-2.1	0.0
No Change	71371712	-24	71371688	3.6	3.6	0.0	1.0	100	-1.3	-1.3	0.0
No Change	71371678	10	71371688	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71371649	39	71371688	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0

861C>A

Instruction: g71371658t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	71371678	10	71371688	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71371649	39	71371688	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71371610	78	71371688	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0
increased	71371661	27	71371688	-1.8	1.2	3.1	2.3	234.7	-3.0	-2.1	0.9

862G>A

Instruction: c71371657t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	71371678	10	71371688	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71371649	39	71371688	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71371610	78	71371688	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0

866C>T

Instruction: g71371653a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	71371678	10	71371688	3.2	3.2	0.0	1.0	100	-1.5	-1.5	0.0
No Change	71371649	39	71371688	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71371610	78	71371688	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71371607	81	71371688	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0

906C>G

Instruction: g71371613c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71371563	-8	71371555	3.3	3.3	0.0	1.0	100	-1.2	-1.2	0.0
Sites found for donor
No Change	71371649	-94	71371555	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
Decreased	71371610	-55	71371555	1.8	0.6	-1.2	-2.2	44.7	-1.9	-2.3	-0.4
No Change	71371607	-52	71371555	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71371587	-32	71371555	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0

920G>A

Instruction: c71371599t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71371563	-8	71371555	3.3	3.3	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71371556	-1	71371555	8.0	8.0	0.0	1.0	100	-0.2	-0.2	0.0
Sites found for donor
No Change	71371649	-94	71371555	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	71371610	-55	71371555	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0
No Change	71371607	-52	71371555	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	71371587	-32	71371555	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
No Change	71371555	0	71371555	11.1	11.1	0.0	1.0	100	0.9	0.9	0.0

925G>A

Instruction: c71371594t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	71371563	-8	71371555	3.3	3