CYP3A4 allele nomenclature 
Allele
Protein__
Nucleotide changes     
Trivial name
Effect
Enzyme_activity
References
cDNA M18907
 

 
S222P
 
 
Sata et al, 2000
CYP3A4*3
CYP3A4.3
1334T>C

 
M445T
 
 
Sata et al, 2000
CYP3A4*4
CYP3A4.4
352A>G

 
I118V
 
 
Hsieh et al, 2001
CYP3A4*5
CYP3A4.5
653C>G

 
P218R
 
 
Hsieh et al, 2001
CYP3A4*6
 
831insA

 
frameshift
 
 
Hsieh et al, 2001
CYP3A4*7
CYP3A4.7
167G>A

 
G56D
 
 
Eiselt et al, 2001
CYP3A4*8
CYP3A4.8
389G>A

 
R130Q
 
 
Eiselt et al, 2001
CYP3A4*9
CYP3A4.9
508G>A

 
V170I
 
 
Eiselt et al, 2001
CYP3A4*10
CYP3A4.10
520G>C

 
D174H
 
 
Eiselt et al, 2001
CYP3A4*11
CYP3A4.11
1088C>T

 
T363M
 
 
Eiselt et al, 2001
CYP3A4*12
CYP3A4.12
1117C>T

 
L373F
 
 
Eiselt et al, 2001
CYP3A4*13
CYP3A4.13
1247C>T

 
P416L
 
 
Eiselt et al, 2001
CYP3A4*14
CYP3A4.14
44T>C

 
L15P
 
 
Lamba et al, 2002
CYP3A4*15A
CYP3A4.15
485G>A

 
R162Q
 
 
Lamba et al, 2002
CYP3A4*15B
CYP3A4.15
-845insATGGAGTGA + -392A>G + 485G>A

 
R162Q
 
 
Hamzeiy et al, 2002
CYP3A4*16A
CYP3A4.18
554C>G

 
T185S
 
 
Lamba et al, 2002
CYP3A4*16B
CYP3A4.18
554C>G +  IVS10+12G>A




T185S




Fukushima-Uesaka et al, 2004
CYP3A4*17
CYP3A4.17
566T>C

 
F189S
 
Decr
Dai et al, 2001
CYP3A4*18A
CYP3A4.18
878T>C

 
L293P
 
Incr 
Dai et al, 2001
CYP3A4*18B
CYP3A4.18
878T>C + IVS10+12G>A




L293P




Fukushima-Uesaka et al, 2004

CYP3A4*19
CYP3A4.19
1399C>T + IVS10+12G>A

 
P467S
 
 
Dai et al, 2001
SwissProt OMIM GeneCards


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CYP2D6 CYP2E1 CYP2J2 CYP2S1 CYP3A4 CYP3A5 CYP3A7 CYP3A43 CYP4B1 CYP5A1 CYP8A1 CYP21A2

 This page was updated 19-May-2004 by Sarah Malmebo 
Questions and comments are always welcome