Gene: CYP3A4
mRNA Accession: M18907
Chromosome: chr 7

Sequence Walker  




1334T>C


Instruction: a98956119g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98956080 12098956200 1.1 1.1 0.0 1.0100 -1.7 -1.7 0.0
No Change 98956070 13098956200 3.4 3.4 0.0 1.0100 -1.2 -1.2 0.0
Sites found for donor
No Change 98956143 5798956200 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 98956115 8598956200 2.0 2.0 0.0 1.0100 -1.8 -1.8 0.0



352A>G


Instruction: t98965420c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98965441 1398965454 6.0 6.0 0.0 1.0100 -0.6 -0.6 0.0
Increased 98965411 4398965454 2.5 3.0 0.4 1.3133.5 -1.4 -1.3 0.1
Sites found for donor
No Change 98965441 1398965454 2.6 2.6 0.0 1.0100 -1.7 -1.7 0.0
increased989654252998965454 -0.0 0.4 0.4 1.3127.5 -2.4 -2.3 0.1



653C>G


Instruction: g98963589c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased98963575 -4 98963571 3.2 1.9 -1.3 -2.540.5 -1.2 -1.5 -0.3
Decreased98963572 -1 98963571 3.2 1.9 -1.3 -2.540.3 -1.2 -1.5 -0.3
Decreased98963571 0 98963571 3.2 2.4 -0.8 -1.855.6 -1.2 -1.4 -0.2
No Change 98963538 3398963571 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
Decreased98963574-398963571 0.6 -0.5 -1.1 -1.5NA -1.8 -2.0 -0.2
Sites found for donor
No Change 98963571 098963571 5.4 5.4 0.0 1.0100 -0.8 -0.8 0.0



831insA


Instruction: i98961628,98961629t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98961657 598961662 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 98961655 798961662 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 98961641 2198961662 4.5 4.5 0.0 1.0100 -1.0 -1.0 0.0
Decreased98961623 39 98961662 5.1 3.5 -1.6 -3.033.4 -0.8 -1.2 -0.3
Sites found for donor
No Change 98961655 798961662 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 98961594 6898961662 7.2 7.2 0.0 1.0100 -0.2 -0.2 0.0



167G>A


Instruction: c98973297t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Increased 98973299 098973299 14.9 14.9 0.0 1.0103.1 1.3 1.3 0.0
Decreased98973298 1 98973299 2.5 1.5 -1.0 -1.951.5 -1.4 -1.6 -0.2
Sites found for donor
No Change 98973348 -4998973299 1.5 1.5 0.0 1.0100 -2.0 -2.0 0.0
No Change 98973344 -4598973299 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 98973291 898973299 2.1 2.1 0.0 1.0100 -1.8 -1.8 0.0
No Change 98973263 3698973299 5.2 5.2 0.0 1.0100 -0.9 -0.9 0.0
No Change 98973253 4698973299 5.2 5.2 0.0 1.0100 -0.9 -0.9 0.0
No Change 98973251 4898973299 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0



389G>A


Instruction: c98965383t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98965411 -7298965339 2.5 2.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 98965356 -1798965339 4.8 4.8 0.0 1.0100 -0.9 -0.9 0.0
Sites found for donor
No Change 98965339 098965339 6.9 6.9 0.0 1.0100 -0.3 -0.3 0.0



508G>A


Instruction: c98964999t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor
No Change 98965044 -5998964985 0.0 0.0 0.0 1.0100 -2.4 -2.4 0.0
No Change 98965038 -5398964985 7.0 7.0 0.0 1.0100 -0.3 -0.3 0.0
No Change 98965007 -2298964985 3.6 3.6 0.0 1.0100 -1.3 -1.3 0.0
No Change 98964985 098964985 7.2 7.2 0.0 1.0100 -0.2 -0.2 0.0
No Change 98964981 498964985 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0



520G>C


Instruction: c98964987g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98964936 4998964985 3.9 3.9 0.0 1.0100 -1.1 -1.1 0.0
Sites found for donor
No Change 98965038 -5398964985 7.0 7.0 0.0 1.0100 -0.3 -0.3 0.0
No Change 98965007 -2298964985 3.6 3.6 0.0 1.0100 -1.3 -1.3 0.0
Increased 98964985 098964985 7.2 7.5 0.3 1.2120.0 -0.2 -0.2 0.1
No Change 98964981 498964985 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0



1088C>T


Instruction: g98957424a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor
No Change 98957437 4998957486 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 98957434 5298957486 5.9 5.9 0.0 1.0100 -0.6 -0.6 0.0
No Change 98957386 10098957486 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0



1117C>T


Instruction: g98957395a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor
No Change 98957437 4998957486 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 98957434 5298957486 5.9 5.9 0.0 1.0100 -0.6 -0.6 0.0
No Change 98957386 10098957486 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 98957370 11698957486 0.1 0.1 0.0 1.0100 -2.4 -2.4 0.0



1247C>T


Instruction: g98957265a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98957294 -3698957258 0.4 0.4 0.0 1.0100 -1.8 -1.8 0.0
Increased 98957259 -198957258 1.3 1.5 0.2 1.1111.1 -1.6 -1.6 0.0
Sites found for donor
No Change 98957304 -4698957258 0.5 0.5 0.0 1.0100 -2.3 -2.3 0.0
No Change 98957294 -3698957258 1.7 1.7 0.0 1.0100 -1.9 -1.9 0.0
No Change 98957258 098957258 4.8 4.8 0.0 1.0100 -1.0 -1.0 0.0
No Change 98957244 1498957258 1.6 1.6 0.0 1.0100 -2.0 -2.0 0.0



44T>C


Instruction: a98979256g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 98979284 -5698979228 3.7 3.7 0.0 1.0100 -1.1 -1.1 0.0
Decreased98979247 -19 98979228 4.3 3.7 -0.6 -1.566.7 -1.0 -1.1 -0.1
No Change 98979224 498979228 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 98979213 1598979228 3.8 3.8 0.0 1.0100 -1.1 -1.1 0.0
Sites found for donor
No Change 98979305 -7798979228 1.8 1.8 0.0 1.0100 -1.9 -1.9 0.0
No Change 98979302 -7498979228 1.3 1.3 0.0 1.0100 -2.1 -2.1 0.0
No Change 98979242 -1498979228 1.6 1.6 0.0 1.0100 -1.9 -1.9 0.0
No Change 98979228 098979228 5.4 5.4 0.0 1.0100 -0.8 -0.8 0.0
No Change 98979224 498979228 2.2 2.2 0.0 1.0100 -1.8 -1.8 0.0



485G>A


Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Unprocessed due to the following error. -845insATGGAGTGA.-392A>G.485G>A the old base at 98965380 is NOT t! It is g.



-845insATGGAGTGA.-392A>G.485G>A


Instruction: ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor



554C>G


Instruction: g98963688c g98963688c.c98959061t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor



554C>G.IVS10+12G>A


Instruction: g98963688c.c98959061t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor



566T>C


Instruction: a98963676g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor



878T>C


Instruction: a98959221g a98959221g.c98959061t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor



878T>C.IVS10+12G>A


Instruction: a98959221g.c98959061t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor



1399C>T.IVS10+12G>A


Instruction: g98956054a.c98959061t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor