All Mutations grouped

Gene:	CTNS
mRNA Accession:	AJ222967
Chromosome:	chr 17
Sequence Walker

340A>C

Instruction: a3494310c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3494289	-1	3494290	2.5	2.5	0.0	1.0	100	-1.4	-1.4	0.0
No Change	3494290	0	3494290	13.1	13.1	0.0	1.0	100	0.9	0.9	0.0
No Change	3494295	5	3494290	4.0	4.0	0.0	1.0	100	-1.1	-1.1	0.0
No Change	3494297	7	3494290	5.3	5.3	0.0	1.0	100	-0.8	-0.8	0.0
No Change	3494351	61	3494290	6.6	6.6	0.0	1.0	100	-0.5	-0.5	0.0
No Change	3494353	63	3494290	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
No Change	3494354	64	3494290	11.8	11.8	0.0	1.0	100	0.6	0.6	0.0
No Change	3494361	71	3494290	6.3	6.3	0.0	1.0	100	-0.6	-0.6	0.0
Sites found for donor

342G>A

Instruction: g3494312a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3494289	-1	3494290	2.5	2.5	0.0	1.0	100	-1.4	-1.4	0.0
No Change	3494290	0	3494290	13.1	13.1	0.0	1.0	100	0.9	0.9	0.0
No Change	3494295	5	3494290	4.0	4.0	0.0	1.0	100	-1.1	-1.1	0.0
No Change	3494297	7	3494290	5.3	5.3	0.0	1.0	100	-0.8	-0.8	0.0
No Change	3494351	61	3494290	6.6	6.6	0.0	1.0	100	-0.5	-0.5	0.0
No Change	3494353	63	3494290	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
No Change	3494354	64	3494290	11.8	11.8	0.0	1.0	100	0.6	0.6	0.0
No Change	3494361	71	3494290	6.3	6.3	0.0	1.0	100	-0.6	-0.6	0.0
Sites found for donor

354G>A

Instruction: g3494324a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3494295	5	3494290	4.0	4.0	0.0	1.0	100	-1.1	-1.1	0.0
No Change	3494297	7	3494290	5.3	5.3	0.0	1.0	100	-0.8	-0.8	0.0
No Change	3494351	61	3494290	6.6	6.6	0.0	1.0	100	-0.5	-0.5	0.0
No Change	3494353	63	3494290	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
No Change	3494354	64	3494290	11.8	11.8	0.0	1.0	100	0.6	0.6	0.0
No Change	3494361	71	3494290	6.3	6.3	0.0	1.0	100	-0.6	-0.6	0.0
Sites found for donor
No Change	3494368	78	3494290	0.8	0.8	0.0	1.0	100	-2.2	-2.2	0.0
No Change	3494371	81	3494290	8.9	8.9	0.0	1.0	100	0.3	0.3	0.0

564+1G>A

Instruction: g3503035a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3503029	-6	3503035	0.4	0.4	0.0	1.0	100	-1.9	-1.9	0.0
Decreased	3503035	0	3503035	1.1	-6.5	-7.6	-2.1	NA	-1.7	-3.4	-1.7
Sites found for donor
No Change	3503039	4	3503035	2.7	2.7	0.0	1.0	100	-1.6	-1.6	0.0
No Change	3503060	25	3503035	5.1	5.1	0.0	1.0	100	-0.9	-0.9	0.0
No Change	3503075	40	3503035	6.0	6.0	0.0	1.0	100	-0.6	-0.6	0.0
Decreased	3503035	0	3503035	8.5	-4.3	-12.8	-367.1	NA	0.2	-3.7	-3.9

1004A>G

Instruction: a3510882g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3510924	25	3510899	5.2	5.2	0.0	1.0	100	-0.8	-0.8	0.0
No Change	3510934	35	3510899	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
Decreased	3510883	-16	3510899	4.1	-4.1	-8.2	-16.8	NA	-1.0	-2.8	-1.8
Sites found for donor
No Change	3510892	-7	3510899	3.1	3.1	0.0	1.0	100	-1.5	-1.5	0.0
No Change	3510899	0	3510899	9.4	9.4	0.0	1.0	100	0.4	0.4	0.0
increased	3510878	-21	3510899	-2.3	1.2	3.5	2.3	227.6	-3.1	-2.1	1.1
increased	3510883	-16	3510899	-2.3	0.7	3.1	1.7	165.3	-3.1	-2.2	0.9

1020G>A

Instruction: g3510898a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3510883	-16	3510899	4.1	4.1	0.0	1.0	100	-1.0	-1.0	0.0
No Change	3510924	25	3510899	5.2	5.2	0.0	1.0	100	-0.8	-0.8	0.0
No Change	3510934	35	3510899	1.9	1.9	0.0	1.0	100	-1.5	-1.5	0.0
Sites found for donor
Decreased	3510892	-7	3510899	3.1	2.7	-0.4	-1.3	75.8	-1.5	-1.6	-0.1
Decreased	3510899	0	3510899	9.4	6.3	-3.1	-8.3	12.0	0.4	-0.5	-0.9

1192-2A>G

Instruction: a3513959g ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3513954	-6	3513960	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
Decreased	3513960	0	3513960	7.9	-0.2	-8.2	-244.2	NA	-0.2	-2.0	-1.8
Sites found for donor

1203C>A

Instruction: c3513972a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3513954	-6	3513960	1.6	1.6	0.0	1.0	100	-1.6	-1.6	0.0
No Change	3513960	0	3513960	7.9	7.9	0.0	1.0	100	-0.2	-0.2	0.0
Sites found for donor

1386-1387ins12

Instruction: i3512952,351295312 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	3512973	-1365	3514338	0.5	0.0	-0.5	-1.4	71.3	-1.8	0.0	1.8
Sites found for donor
Decreased	3513000	-1338	3514338	5.3	0.0	-5.3	-38.6	2.5	-0.8	0.0	0.8

668G>T

Instruction: g3509204t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3509181	-24	3509205	0.4	0.4	0.0	1.0	100	-1.9	-1.9	0.0
Increased	3509219	14	3509205	0.1	1.4	1.3	2.5	251.4	-1.9	-1.6	0.3
Sites found for donor
No Change	3509155	-50	3509205	0.4	0.4	0.0	1.0	100	-2.3	-2.3	0.0
Decreased	3509205	0	3509205	5.9	2.6	-3.3	-10.0	10.0	-0.6	-1.6	-1.0
No Change	3509221	16	3509205	5.8	5.8	0.0	1.0	100	-0.7	-0.7	0.0
No Change	3509223	18	3509205	1.7	1.7	0.0	1.0	100	-1.9	-1.9	0.0
No Change	3509236	31	3509205	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0

869A>C

Instruction: a3510658c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3510649	-41	3510690	3.6	3.6	0.0	1.0	100	-1.1	-1.1	0.0
No Change	3510689	-1	3510690	3.2	3.2	0.0	1.0	100	-1.2	-1.2	0.0
Sites found for donor
No Change	3510690	0	3510690	8.1	8.1	0.0	1.0	100	0.0	0.0	0.0

938C>T

Instruction: c3510816t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	3510843	65	3510778	2.5	2.5	0.0	1.0	100	-1.4	-1.4	0.0
No Change	3510850	72	3510778	1.7	1.7	0.0	1.0	100	-1.6	-1.6	0.0
Sites found for donor
No Change	3510809	31	3510778	0.7	0.7	0.0	1.0	100	-2.2	-2.2	0.0
Decreased	3510818	40	3510778	1.3	1.2	-0.1	-1.1	93.5	-2.0	-2.1	-0.0