All Mutations grouped

Gene:	CHM
mRNA Accession:	X78121
Chromosome:	chr X
Sequence Walker

47delC

Instruction: d83338249,83338249 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83338266	-50	83338216	2.8	2.8	0.0	1.0	100	-1.3	-1.3	0.0
Decreased	83338242	-26	83338216	0.3	-0.2	-0.6	-1.2	NA	-1.9	-2.0	-0.1
Sites found for donor
No Change	83338296	-80	83338216	4.6	4.6	0.0	1.0	100	-1.0	-1.0	0.0
No Change	83338235	-19	83338216	2.9	2.9	0.0	1.0	100	-1.5	-1.5	0.0
No Change	83338229	-13	83338216	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	83338216	0	83338216	7.7	7.7	0.0	1.0	100	-0.1	-0.1	0.0
No Change	83338202	14	83338216	3.0	3.0	0.0	1.0	100	-1.5	-1.5	0.0

79+1G>A

Instruction: c83338216t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83338242	-26	83338216	0.3	0.3	0.0	1.0	100	-1.9	-1.9	0.0
Sites found for donor
No Change	83338235	-19	83338216	2.9	2.9	0.0	1.0	100	-1.5	-1.5	0.0
No Change	83338229	-13	83338216	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	83338202	14	83338216	3.0	3.0	0.0	1.0	100	-1.5	-1.5	0.0
Decreased	83338216	0	83338216	7.7	-5.1	-12.8	-214.9	NA	-0.1	-4.0	-3.9

146+1G>A

Instruction: c83318223t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83318174	49	83318223	7.5	7.5	0.0	1.0	100	-0.3	-0.3	0.0
Sites found for donor
No Change	83318251	-28	83318223	0.6	0.6	0.0	1.0	100	-2.3	-2.3	0.0
No Change	83318244	-21	83318223	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	83318223	0	83318223	4.4	-8.4	-12.8	-21.6	NA	-1.1	-5.0	-3.9

160G>T

Instruction: c83272529a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83272554	-11	83272543	0.4	0.4	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83272553	-10	83272543	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	83272552	-9	83272543	8.7	8.7	0.0	1.0	100	-0.0	-0.0	0.0
No Change	83272551	-8	83272543	4.4	4.4	0.0	1.0	100	-1.0	-1.0	0.0
No Change	83272550	-7	83272543	0.2	0.2	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83272549	-6	83272543	6.5	6.5	0.0	1.0	100	-0.5	-0.5	0.0
No Change	83272545	-2	83272543	3.5	3.5	0.0	1.0	100	-1.2	-1.2	0.0
No Change	83272543	0	83272543	12.1	12.1	0.0	1.0	100	0.7	0.7	0.0
No Change	83272540	3	83272543	3.5	3.5	0.0	1.0	100	-1.2	-1.2	0.0
No Change	83272499	44	83272543	8.0	8.0	0.0	1.0	100	-0.2	-0.2	0.0
No Change	83272479	64	83272543	3.3	3.3	0.0	1.0	100	-1.2	-1.2	0.0
Sites found for donor
No Change	83272525	18	83272543	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0

555_556delAG

Instruction: d83254575,83254576 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83254524	263	83254787	3.7	3.7	0.0	1.0	100	-1.1	-1.1	0.0
Sites found for donor
No Change	83254596	191	83254787	5.4	5.4	0.0	1.0	100	-0.8	-0.8	0.0
No Change	83254589	198	83254787	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0
Increased	83254581	206	83254787	3.0	3.3	0.4	1.3	128.8	-1.5	-1.4	0.1
No Change	83254556	231	83254787	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83254541	246	83254787	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0

559delG

Instruction: d83254572,83254572 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83254524	-126	83254398	3.7	3.7	0.0	1.0	100	-1.1	-1.1	0.0
No Change	83254521	-123	83254398	3.3	3.3	0.0	1.0	100	-1.2	-1.2	0.0
Sites found for donor
No Change	83254596	-198	83254398	5.4	5.4	0.0	1.0	100	-0.8	-0.8	0.0
No Change	83254589	-191	83254398	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83254581	-183	83254398	3.0	3.0	0.0	1.0	100	-1.5	-1.5	0.0
No Change	83254556	-158	83254398	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83254541	-143	83254398	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0

579_587delTGATAAAACinsAGTTTTCT

Instruction: i83254544,83254554agaaaact ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	83254524	-126	83254398	3.7	5.7	2.0	4.1	407.7	-1.1	-0.7	0.4
Decreased	83254521	-123	83254398	3.3	4.1	0.8	1.7	174.5	-1.2	-1.0	0.2
increased	83254525	-127	83254398	-13.8	5.7	19.5	52.9	5289.7	-4.9	-0.7	4.3
increased	83254522	-124	83254398	-15.1	4.1	19.2	17.3	1731.9	-5.2	-1.0	4.2
Sites found for donor
Decreased	83254581	-183	83254398	3.0	1.8	-1.1	-2.2	45.5	-1.5	-1.9	-0.3
Decreased	83254589	-191	83254398	1.8	-9.6	-11.4	-3.6	NA	-1.9	-5.3	-3.5
Decreased	83254556	-158	83254398	1.6	-18.9	-20.5	-3.0	NA	-1.9	-8.2	-6.2
Decreased	83254541	-143	83254398	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	83254511	-113	83254398	0.3	0.3	0.0	1.0	100	-2.3	-2.3	0.0
Decreased	83254503	-105	83254398	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0
increased	83254573	-175	83254398	-3.0	3.0	6.0	7.9	788.8	-3.4	-1.5	1.8
increased	83254548	-150	83254398	-16.8	6.2	23.0	73.9	7385.9	-7.5	-0.5	7.0
increased	83254542	-144	83254398	-21.2	2.2	23.4	4.5	449.9	-8.9	-1.8	7.1
increased	83254512	-114	83254398	-22.7	0.3	23.0	1.2	121.6	-9.3	-2.3	7.0
increased	83254504	-106	83254398	-19.5	1.8	21.3	3.6	358.9	-8.4	-1.9	6.5

599C>G

Instruction: g83254532c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	83254524	-126	83254398	3.7	2.1	-1.6	-3.0	32.9	-1.1	-1.5	-0.4
Decreased	83254521	-123	83254398	3.3	1.6	-1.7	-3.3	30.3	-1.2	-1.6	-0.4
Sites found for donor
No Change	83254581	-183	83254398	3.0	3.0	0.0	1.0	100	-1.5	-1.5	0.0
No Change	83254556	-158	83254398	1.6	1.6	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83254541	-143	83254398	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
No Change	83254511	-113	83254398	0.3	0.3	0.0	1.0	100	-2.3	-2.3	0.0
No Change	83254503	-105	83254398	1.8	1.8	0.0	1.0	100	-1.9	-1.9	0.0

682_685delTCAC

Instruction: d83254446,83254449 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83254399	388	83254787	1.1	1.1	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
No Change	83254430	357	83254787	1.3	1.3	0.0	1.0	100	-2.0	-2.0	0.0
No Change	83254426	361	83254787	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0
No Change	83254398	389	83254787	12.6	12.6	0.0	1.0	100	1.4	1.4	0.0

745C>T

Instruction: g83249699a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83249714	-2	83249712	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
No Change	83249712	0	83249712	8.0	8.0	0.0	1.0	100	-0.2	-0.2	0.0
Decreased	83249696	16	83249712	3.1	2.8	-0.3	-1.2	82.3	-1.3	-1.3	-0.1
No Change	83249648	64	83249712	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
Sites found for donor
No Change	83249733	-21	83249712	1.7	1.7	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83249663	49	83249712	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0

757delAAinsT

Instruction: d83249686,83249687 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83249714	-2	83249712	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
No Change	83249712	0	83249712	8.0	8.0	0.0	1.0	100	-0.2	-0.2	0.0
No Change	83249696	16	83249712	3.1	3.1	0.0	1.0	100	-1.3	-1.3	0.0
No Change	83249648	64	83249712	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
Sites found for donor
No Change	83249733	-21	83249712	1.7	1.7	0.0	1.0	100	-1.9	-1.9	0.0
No Change	83249663	49	83249712	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0

787C>T

Instruction: g83249657a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	83249648	64	83249712	2.4	3.0	0.6	1.5	149.8	-1.4	-1.3	0.1
No Change	83249612	100	83249712	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	83249609	103	83249712	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
Decreased	83249663	49	83249712	4.5	4.2	-0.3	-1.2	80.2	-1.1	-1.1	-0.1

798delG

Instruction: d83249646,83249646 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	83249648	-54	83249594	2.4	2.9	0.5	1.4	142.8	-1.4	-1.3	0.1
No Change	83249612	-18	83249594	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	83249609	-15	83249594	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
No Change	83249663	-69	83249594	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0

829C>T

Instruction: g83249615a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	83249612	-18	83249594	2.3	2.0	-0.3	-1.2	82.3	-1.4	-1.5	-0.1
Increased	83249609	-15	83249594	0.9	1.0	0.2	1.1	111.1	-1.7	-1.7	0.0
Sites found for donor
No Change	83249663	-69	83249594	4.5	4.5	0.0	1.0	100	-1.1	-1.1	0.0
No Change	83249594	0	83249594	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	83249573	21	83249594	3.6	3.6	0.0	1.0	100	-1.3	-1.3	0.0

838C>T

Instruction: g83249606a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83249612	-18	83249594	2.3	2.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	83249609	-15	83249594	0.9	0.9	0.0	1.0	100	-1.7	-1.7	0.0
Sites found for donor
No Change	83249594	0	83249594	4.0	4.0	0.0	1.0	100	-1.2	-1.2	0.0
No Change	83249573	21	83249594	3.6	3.6	0.0	1.0	100	-1.3	-1.3	0.0

907C>T

Instruction: g83248652a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	83248661	49	83248710	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	83248624	86	83248710	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
increased	83248653	57	83248710	-1.5	6.0	7.5	64.0	6403.2	-2.9	-0.6	2.3

934delT

Instruction: d83248625,83248625 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	83248661	-73	83248588	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	83248624	-36	83248588	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	83248588	0	83248588	5.0	5.0	0.0	1.0	100	-0.9	-0.9	0.0

970+1G>T

Instruction: c83248588a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	83248572	16	83248588	2.4	3.8	1.4	2.6	259.7	-1.4	-1.1	0.3
Increased	83248569	19	83248588	3.0	4.1	1.1	2.1	214.2	-1.3	-1.0	0.2
Sites found for donor
No Change	83248624	-36	83248588	1.4	1.4	0.0	1.0	100	-2.0	-2.0	0.0
No Change	83248572	16	83248588	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0
Decreased	83248588	0	83248588	5.0	-2.8	-7.8	-32.7	NA	-0.9	-3.3	-2.4
increased	83248589	-1	83248588	-7.6	0.6	8.2	1.5	148.3	-4.8	-2.3	2.5

1009delC

Instruction: d83247074,83247074 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor

1049C>A

Instruction: g83247034t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor

1248C>A

Instruction: g83202021t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83202029	-35	83201994	7.0	7.0	0.0	1.0	100	-0.4	-0.4	0.0
No Change	83202024	-30	83201994	5.7	5.7	0.0	1.0	100	-0.7	-0.7	0.0
Decreased	83202014	-20	83201994	2.4	0.5	-1.9	-3.8	26.2	-1.4	-1.8	-0.4
Sites found for donor
No Change	83202069	-75	83201994	2.8	2.8	0.0	1.0	100	-1.6	-1.6	0.0
No Change	83202055	-61	83201994	0.4	0.4	0.0	1.0	100	-2.3	-2.3	0.0
No Change	83201994	0	83201994	8.3	8.3	0.0	1.0	100	0.1	0.1	0.0
No Change	83201979	15	83201994	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
increased	83202024	-30	83201994	-0.5	2.6	3.1	6.1	612.4	-2.6	-1.6	0.9

1274+1G>A

Instruction: c83201994t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83202014	-20	83201994	2.4	2.4	0.0	1.0	100	-1.4	-1.4	0.0
Sites found for donor
No Change	83201979	15	83201994	2.2	2.2	0.0	1.0	100	-1.8	-1.8	0.0
Decreased	83201994	0	83201994	8.3	-4.5	-12.8	-315.2	NA	0.1	-3.8	-3.9

1319delA

Instruction: d83191878,83191878 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Increased	83191862	61	83191923	2.5	4.0	1.4	2.7	272.0	-1.4	-1.1	0.3
Sites found for donor
No Change	83191920	3	83191923	3.3	3.3	0.0	1.0	100	-1.4	-1.4	0.0
No Change	83191896	27	83191923	3.0	3.0	0.0	1.0	100	-1.5	-1.5	0.0
No Change	83191838	85	83191923	0.6	0.6	0.0	1.0	100	-2.2	-2.2	0.0
No Change	83191830	93	83191923	3.8	3.8	0.0	1.0	100	-1.3	-1.3	0.0

1380-6T>G

Instruction: a83191449c ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	83191444	0	83191444	9.9	7.0	-2.8	-7.2	13.9	0.2	-0.4	-0.6
Decreased	83191440	4	83191444	3.7	1.5	-2.2	-4.6	21.8	-1.1	-1.6	-0.5
Decreased	83191432	12	83191444	1.7	0.1	-1.5	-2.9	34.2	-1.6	-1.9	-0.3
No Change	83191415	29	83191444	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
increased	83191449	-5	83191444	-0.9	7.8	8.7	226.1	22612.7	-2.1	-0.2	1.9
Sites found for donor
No Change	83191431	13	83191444	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

1380-1G>A

Instruction: c83191444t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	83191444	0	83191444	9.9	2.3	-7.6	-191.1	0.5	0.2	-1.4	-1.7
Increased	83191440	4	83191444	3.7	4.0	0.3	1.2	123.3	-1.1	-1.1	0.1
Decreased	83191432	12	83191444	1.7	1.2	-0.5	-1.4	70.1	-1.6	-1.7	-0.1
No Change	83191415	29	83191444	1.4	1.4	0.0	1.0	100	-1.6	-1.6	0.0
increased	83191443	1	83191444	-6.3	1.8	8.2	3.6	357.0	-3.3	-1.5	1.8
Sites found for donor
No Change	83191431	13	83191444	0.1	0.1	0.0	1.0	100	-2.4	-2.4	0.0

1393delG

Instruction: d83191430,83191430 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
No Change	83191444	0	83191444	9.9	9.9	0.0	1.0	100	0.2	0.2	0.0
No Change	83191440	4	83191444	3.7	3.7	0.0	1.0	100	-1.1	-1.1	0.0
Decreased	83191432	12	83191444	1.7	1.3	-0.4	-1.3	74.5	-1.6	-1.7	-0.1
Increased	83191415	29	83191444	1.4	2.2	0.8	1.7	173.5	-1.6	-1.5	0.2
No Change	83191380	64	83191444	0.5	0.5	0.0	1.0	100	-1.8	-1.8	0.0
Sites found for donor
Decreased	83191431	13	83191444	0.1	-5.0	-5.1	-1.1	NA	-2.4	-3.9	-1.5

1542T>A

Instruction: a83169796t ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Decreased	83169798	0	83169798	10.3	9.8	-0.5	-1.4	72.2	0.3	0.2	-0.1
Decreased	83169776	22	83169798	1.0	0.1	-0.9	-1.9	53.7	-1.7	-1.9	-0.2
No Change	83169762	36	83169798	2.9	2.9	0.0	1.0	100	-1.3	-1.3	0.0
increased	83169703	95	83169798	-3.9	0.5	4.3	1.4	136.7	-2.8	-1.8	0.9
increased	83163871	5927	83169798	-0.3	0.2	0.5	1.1	111.2	-2.0	-1.9	0.1
Sites found for donor
No Change	83169847	-49	83169798	2.4	2.4	0.0	1.0	100	-1.7	-1.7	0.0
No Change	83169834	-36	83169798	0.2	0.2	0.0	1.0	100	-2.4	-2.4	0.0

1614_1618delTGTT

Instruction: d83169720,83169724 ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	83169740	58	83169798	0.0	0.0	0.0	1.0	100	-2.4	-2.4	0.0
No Change	83169698	100	83169798	9.5	9.5	0.0	1.0	100	0.5	0.5	0.0

1633G>T

Instruction: c83169705a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	83169740	-42	83169698	0.0	0.0	0.0	1.0	100	-2.4	-2.4	0.0
No Change	83169698	0	83169698	9.5	9.5	0.0	1.0	100	0.5	0.5	0.0
No Change	83169669	29	83169698	0.9	0.9	0.0	1.0	100	-2.2	-2.2	0.0
No Change	83169664	34	83169698	6.9	6.9	0.0	1.0	100	-0.3	-0.3	0.0
No Change	83169659	39	83169698	3.9	3.9	0.0	1.0	100	-1.3	-1.3	0.0
increased	83169706	-8	83169698	-5.0	3.2	8.2	9.0	902.9	-4.0	-1.5	2.5

1693A>T

Instruction: t83163893a ; Sequence Walker
Type of change	Genomic Coordinate	Position Relative to Natural Site	Closest Natural Site	Initial(Ri)	Final(Ri)	Δ Ri	Fold change	% Binding (Final/Initial)	Initial(Z)	Final(z)	Δ Z
Sites found for acceptor
Sites found for donor
No Change	83163935	12	83163947	2.0	2.0	0.0	1.0	100	-1.8	-1.8	0.0
No Change	83163915	32	83163947	0.9	0.9	0.0	1.0	100	-2.2	-2.2	0.0
increased	83163894	53	83163947	-2.5	5.3	7.8	39.4	3936.4	-3.2	-0.8	2.4