Gene: PAH
mRNA Accession: U49897
Mutation:PAH.txt
Chromosome: chr 12

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS1nt5g>t
Sequence Walker  
c103243791a 103243817 -22 103243795 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
IVS1nt5g>t
Sequence Walker  
c103243791a 103243768 27 103243795 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
IVS1nt5g>t
Sequence Walker  
c103243791a 103243767 28 103243795 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS2nt1g>a
Sequence Walker  
c103239515t 103239551 -36 103239515 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt1g>a
Sequence Walker  
c103239515t 103239547 -32 103239515 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS2nt1g>a
Sequence Walker  
c103239515t 103239533 -18 103239515 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS2nt1g>a
Sequence Walker  
c103239515t 103239498 17 103239515 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt5g>c
Sequence Walker  
c103239511g 103239551 -36 103239515 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt5g>c
Sequence Walker  
c103239511g 103239547 -32 103239515 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS2nt5g>c
Sequence Walker  
c103239511g 103239533 -18 103239515 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS2nt5g>c
Sequence Walker  
c103239511g 103239498 17 103239515 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt5g>t
Sequence Walker  
c103239511a 103239551 -36 103239515 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt5g>t
Sequence Walker  
c103239511a 103239547 -32 103239515 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS2nt5g>t
Sequence Walker  
c103239511a 103239533 -18 103239515 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS2nt5g>t
Sequence Walker  
c103239511a 103239498 17 103239515 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt6t>g
Sequence Walker  
a103239510c 103239551 -36 103239515 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt6t>g
Sequence Walker  
a103239510c 103239547 -32 103239515 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS2nt6t>g
Sequence Walker  
a103239510c 103239533 -18 103239515 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS2nt6t>g
Sequence Walker  
a103239510c 103239498 17 103239515 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS2nt19t>c
Sequence Walker  
a103239497g 103239547 -32 103239515 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
IVS2nt19t>c
Sequence Walker  
a103239497g 103239533 -18 103239515 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS2nt19t>c
Sequence Walker  
a103239497g 103239515 0 103239515 7.2 7.2 0.0 1.0 100 -0.3 -0.3 0.0
IVS2nt19t>c
Sequence Walker  
a103239497g 103239453 62 103239515 0.9 0.9 0.0 1.0 100 -2.1 -2.1 0.0
IVS4nt1g>a
Sequence Walker  
c103204186t 103204171 15 103204186 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
IVS4nt-1g>a
Sequence Walker  
c103193389t 103193406 -17 103193389 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0
IVS4nt-5c>g
Sequence Walker  
g103193393c 103193443 -54 103193389 4.4 4.4 0.0 1.0 100 -1.1 -1.1 0.0
IVS4nt-5c>g
Sequence Walker  
g103193393c 103193406 -17 103193389 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0
IVS5nt1delg
Sequence Walker  
d103193320,103193320 103193296 24 103193320 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS5nt1g>a
Sequence Walker  
c103193320t 103193296 24 103193320 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS5nt5delg
Sequence Walker  
d103193316,103193316 103193296 24 103193320 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS5nt54c>g
Sequence Walker  
g103193267c 103193296 24 103193320 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS5nt54c>g
Sequence Walker  
g103193267c 103193245 75 103193320 3.3 3.3 0.0 1.0 100 -1.4 -1.4 0.0
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179714 -38 103179676 3.9 3.9 0.0 1.0 100 -1.2 -1.2 0.0
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179649 27 103179676 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179714 -38 103179676 3.9 3.9 0.0 1.0 100 -1.2 -1.2 0.0
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179649 27 103179676 0.9 0.9 0.0 1.0 100 -2.2 -2.2 0.0
IVS7nt1g>a
Sequence Walker  
c103179539t 103179581 -42 103179539 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
IVS7nt1g>a
Sequence Walker  
c103179539t 103179554 -15 103179539 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0
IVS7nt2t>a
Sequence Walker  
a103179538t 103179581 -42 103179539 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
IVS7nt2t>a
Sequence Walker  
a103179538t 103179554 -15 103179539 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0
IVS7nt5g>a
Sequence Walker  
c103179535t 103179581 -42 103179539 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
IVS7nt5g>a
Sequence Walker  
c103179535t 103179554 -15 103179539 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178453 29 103178482 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178453 -42 103178411 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178406 5 103178411 0.5 0.5 0.0 1.0 100 -2.3 -2.3 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178377 34 103178411 3.6 3.6 0.0 1.0 100 -1.3 -1.3 0.0
IVS8nt-5t>g
Sequence Walker  
a103173681c 103173676 1 103173677 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS8nt-5t>g
Sequence Walker  
a103173681c 103173654 23 103173677 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
IVS8nt-7a>g
Sequence Walker  
t103173683c 103173676 1 103173677 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS8nt-7a>g
Sequence Walker  
t103173683c 103173654 23 103173677 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
IVS9nt6t>a
Sequence Walker  
a103173614t 103173654 -35 103173619 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
IVS9nt6t>a
Sequence Walker  
a103173614t 103173598 21 103173619 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
IVS9nt6t>a
Sequence Walker  
a103173614t 103173591 28 103173619 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
IVS9nt-2a>c
Sequence Walker  
t103171158g 103171186 -29 103171157 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS9nt-2a>c
Sequence Walker  
t103171158g 103171116 41 103171157 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
IVS9nt-5t>a
Sequence Walker  
a103171161t 103171186 -29 103171157 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS9nt-5t>a
Sequence Walker  
a103171161t 103171116 41 103171157 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
IVS10nt1g>a
Sequence Walker  
c103171060t 103171095 -35 103171060 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
IVS10nt1g>a
Sequence Walker  
c103171060t 103171071 -11 103171060 4.6 4.6 0.0 1.0 100 -1.0 -1.0 0.0
IVS10nt1g>a
Sequence Walker  
c103171060t 103171024 36 103171060 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS10nt1g>a
Sequence Walker  
c103171060t 103171021 39 103171060 6.5 6.5 0.0 1.0 100 -0.5 -0.5 0.0
IVS10nt1g>a
Sequence Walker  
c103171060t 103171017 43 103171060 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
IVS10nt3a>g
Sequence Walker  
t103171058c 103171095 -35 103171060 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
IVS10nt3a>g
Sequence Walker  
t103171058c 103171071 -11 103171060 4.6 4.6 0.0 1.0 100 -1.0 -1.0 0.0
IVS10nt3a>g
Sequence Walker  
t103171058c 103171024 36 103171060 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS10nt3a>g
Sequence Walker  
t103171058c 103171021 39 103171060 6.5 6.5 0.0 1.0 100 -0.5 -0.5 0.0
IVS10nt3a>g
Sequence Walker  
t103171058c 103171017 43 103171060 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
IVS10nt-11g>a
Sequence Walker  
c103170515t 103170535 -30 103170505 1.6 1.6 0.0 1.0 100 -2.0 -2.0 0.0
IVS10nt-3c>t
Sequence Walker  
g103170507a 103170535 -30 103170505 1.6 1.6 0.0 1.0 100 -2.0 -2.0 0.0
IVS11nt1g>a
Sequence Walker  
c103170370t 103170365 5 103170370 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS11nt1g>a
Sequence Walker  
c103170370t 103170362 8 103170370 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS11nt1g>a
Sequence Walker  
c103170370t 103170353 17 103170370 10.5 10.5 0.0 1.0 100 0.8 0.8 0.0
IVS11nt1g>c
Sequence Walker  
c103170370g 103170365 5 103170370 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS11nt1g>c
Sequence Walker  
c103170370g 103170362 8 103170370 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS11nt1g>c
Sequence Walker  
c103170370g 103170353 17 103170370 10.5 10.5 0.0 1.0 100 0.8 0.8 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170375 -5 103170370 7.8 7.8 0.0 1.0 100 -0.1 -0.1 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170370 0 103170370 10.4 10.4 0.0 1.0 100 0.7 0.7 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170365 5 103170370 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170362 8 103170370 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170321 49 103170370 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170308 62 103170370 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
IVS11nt20g>c
Sequence Walker  
c103170351g 103170304 66 103170370 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0
IVS11nt-8g>a
Sequence Walker  
c103167248t 103167275 -34 103167241 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS12nt2t>c
Sequence Walker  
a103167123g 103167085 39 103167124 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165975 -31 103165944 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165959 -15 103165944 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165943 1 103165944 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165903 41 103165944 4.6 4.6 0.0 1.0 100 -1.0 -1.0 0.0
IVS12nt-35c>t
Sequence Walker  
g103165978a 103165959 -15 103165944 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
IVS12nt-35c>t
Sequence Walker  
g103165978a 103165947 -3 103165944 3.5 3.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS12nt-35c>t
Sequence Walker  
g103165978a 103165943 1 103165944 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0