Gene: PAH
mRNA Accession: U49897
Mutation:PAH.txt
Chromosome: chr 12

Sequence Walker  


Information Increased
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS2nt6t>g
Sequence Walker  
a103239510c 103239511 4 103239515 -0.8 1.4 2.2 2.7 266.0 -2.1 -1.6 0.5
IVS3nt-22c>t
Sequence Walker  
g103204297a 103204276 0 103204276 7.6 7.6 0.1 1.0 104.0 -0.3 -0.3 0.0
IVS4nt-1g>a
Sequence Walker  
c103193389t 103193388 1 103193389 1.5 9.6 8.2 286.2 28616.6 -1.6 0.2 1.8
IVS4nt-1g>a
Sequence Walker  
c103193389t 103193387 2 103193389 -1.5 0.2 1.7 1.2 118.8 -2.3 -1.9 0.4
IVS5nt1delg
Sequence Walker  
d103193320,103193320 103193298 22 103193320 2.6 2.7 0.0 1.0 103.2 -1.4 -1.3 0.0
IVS5nt1g>a
Sequence Walker  
c103193320t 103193298 22 103193320 2.6 3.1 0.4 1.4 135.5 -1.4 -1.3 0.1
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179654 22 103179676 0.6 1.1 0.4 1.4 135.5 -1.8 -1.7 0.1
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179675 1 103179676 -5.1 3.0 8.2 8.2 816.9 -3.1 -1.3 1.8
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179672 4 103179676 -0.2 0.1 0.3 1.0 104.5 -2.0 -1.9 0.1
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179669 7 103179676 2.2 2.5 0.3 1.2 123.0 -1.5 -1.4 0.1
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179667 9 103179676 1.9 2.4 0.4 1.4 135.4 -1.5 -1.4 0.1
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179677 -1 103179676 -0.5 7.0 7.6 130.8 13079.4 -2.1 -0.4 1.7
IVS7nt1g>a
Sequence Walker  
c103179539t 103179522 17 103179539 4.9 5.0 0.1 1.1 109.8 -0.9 -0.8 0.0
IVS7nt1g>a
Sequence Walker  
c103179539t 103179515 24 103179539 4.0 4.4 0.4 1.3 130.5 -1.1 -1.0 0.1
IVS7nt5g>a
Sequence Walker  
c103179535t 103179515 24 103179539 4.0 4.3 0.3 1.2 122.1 -1.1 -1.0 0.1
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178476 6 103178482 -1.5 0.4 2.0 1.3 134.0 -2.3 -1.8 0.4
IVS8nt1g>a
Sequence Walker  
c103178411t 103178407 4 103178411 1.4 1.7 0.3 1.2 123.3 -1.6 -1.6 0.1
IVS8nt-7a>g
Sequence Walker  
t103173683c 103173683 -6 103173677 0.3 7.9 7.6 191.1 19111.1 -1.9 -0.2 1.7
IVS9nt-2a>c
Sequence Walker  
t103171158g 103171149 8 103171157 1.9 3.9 2.0 4.1 407.6 -1.5 -1.1 0.4
IVS9nt-2a>c
Sequence Walker  
t103171158g 103171136 21 103171157 0.2 0.7 0.5 1.4 141.7 -1.9 -1.8 0.1
IVS10nt3a>g
Sequence Walker  
t103171058c 103171046 14 103171060 3.8 4.3 0.5 1.4 142.6 -1.1 -1.0 0.1
IVS10nt-11g>a
Sequence Walker  
c103170515t 103170492 13 103170505 1.8 2.2 0.3 1.2 124.0 -1.5 -1.5 0.1
IVS10nt-11g>a
Sequence Walker  
c103170515t 103170514 -9 103170505 -5.5 2.7 8.2 6.4 636.3 -3.1 -1.4 1.8
IVS10nt-3c>t
Sequence Walker  
g103170507a 103170492 13 103170505 1.8 2.1 0.2 1.2 116.1 -1.5 -1.5 0.0
IVS11nt-8g>a
Sequence Walker  
c103167248t 103167247 -6 103167241 -5.6 2.6 8.2 6.1 608.5 -3.2 -1.4 1.8
IVS12nt2t>c
Sequence Walker  
a103167123g 103167124 0 103167124 3.2 3.5 0.3 1.2 123.5 -1.2 -1.2 0.1