Gene: PAH
mRNA Accession: U49897
Mutation:PAH.txt
Chromosome: chr 12

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS1nt5g>t
Sequence Walker  
c103243791a 103243796 -1 103243795 2.3 2.3 0.0 1.0 100 -1.4 -1.4 0.0
IVS1nt5g>t
Sequence Walker  
c103243791a 103243746 49 103243795 1.9 1.9 0.0 1.0 100 -1.5 -1.5 0.0
IVS2nt1g>a
Sequence Walker  
c103239515t 103239476 39 103239515 0.9 0.9 0.0 1.0 100 -1.7 -1.7 0.0
IVS2nt5g>c
Sequence Walker  
c103239511g 103239476 39 103239515 0.9 0.9 0.0 1.0 100 -1.7 -1.7 0.0
IVS2nt5g>t
Sequence Walker  
c103239511a 103239476 39 103239515 0.9 0.9 0.0 1.0 100 -1.7 -1.7 0.0
IVS2nt6t>g
Sequence Walker  
a103239510c 103239476 39 103239515 0.9 0.9 0.0 1.0 100 -1.7 -1.7 0.0
IVS2nt19t>c
Sequence Walker  
a103239497g 103239453 62 103239515 8.5 8.5 0.0 1.0 100 -0.1 -0.1 0.0
IVS2nt19t>c
Sequence Walker  
a103239497g 103239449 66 103239515 7.9 7.9 0.0 1.0 100 -0.2 -0.2 0.0
IVS3nt-22c>t
Sequence Walker  
g103204297a 103204300 -24 103204276 4.9 4.9 0.0 1.0 100 -0.9 -0.9 0.0
IVS3nt-22c>t
Sequence Walker  
g103204297a 103204269 7 103204276 1.3 1.3 0.0 1.0 100 -1.7 -1.7 0.0
IVS3nt-22c>t
Sequence Walker  
g103204297a 103204261 15 103204276 0.5 0.5 0.0 1.0 100 -1.8 -1.8 0.0
IVS3nt-22c>t
Sequence Walker  
g103204297a 103204260 16 103204276 3.3 3.3 0.0 1.0 100 -1.2 -1.2 0.0
IVS3nt-6t>a
Sequence Walker  
a103204281t 103204300 -24 103204276 4.9 4.9 0.0 1.0 100 -0.9 -0.9 0.0
IVS4nt1g>a
Sequence Walker  
c103204186t 103204138 48 103204186 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
IVS4nt-5c>g
Sequence Walker  
g103193393c 103193421 -32 103193389 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
IVS5nt5delg
Sequence Walker  
d103193316,103193316 103193320 0 103193320 0.4 0.4 0.0 1.0 100 -1.8 -1.8 0.0
IVS5nt54c>g
Sequence Walker  
g103193267c 103193241 79 103193320 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179681 -5 103179676 5.4 5.4 0.0 1.0 100 -0.7 -0.7 0.0
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179669 7 103179676 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179627 49 103179676 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
IVS6nt-1g>a
Sequence Walker  
c103179676t 103179626 50 103179676 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179681 -5 103179676 5.4 5.4 0.0 1.0 100 -0.7 -0.7 0.0
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179627 49 103179676 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
IVS6nt-2a>g
Sequence Walker  
t103179677c 103179626 50 103179676 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0
IVS7nt1g>a
Sequence Walker  
c103179539t 103179508 31 103179539 3.7 3.7 0.0 1.0 100 -1.1 -1.1 0.0
IVS7nt2t>a
Sequence Walker  
a103179538t 103179508 31 103179539 3.7 3.7 0.0 1.0 100 -1.1 -1.1 0.0
IVS7nt5g>a
Sequence Walker  
c103179535t 103179508 31 103179539 3.7 3.7 0.0 1.0 100 -1.1 -1.1 0.0
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178508 -26 103178482 0.9 0.9 0.0 1.0 100 -1.7 -1.7 0.0
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178506 -24 103178482 4.5 4.5 0.0 1.0 100 -1.0 -1.0 0.0
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178490 -8 103178482 1.0 1.0 0.0 1.0 100 -1.7 -1.7 0.0
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178438 44 103178482 7.2 7.2 0.0 1.0 100 -0.4 -0.4 0.0
IVS7nt-2a>t
Sequence Walker  
t103178483a 103178431 51 103178482 7.0 7.0 0.0 1.0 100 -0.4 -0.4 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178438 -27 103178411 7.2 7.2 0.0 1.0 100 -0.4 -0.4 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178431 -20 103178411 7.0 7.0 0.0 1.0 100 -0.4 -0.4 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178421 -10 103178411 2.5 2.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178384 27 103178411 5.1 5.1 0.0 1.0 100 -0.8 -0.8 0.0
IVS8nt1g>a
Sequence Walker  
c103178411t 103178378 33 103178411 8.4 8.4 0.0 1.0 100 -0.1 -0.1 0.0
IVS8nt-7a>g
Sequence Walker  
t103173683c 103173711 -34 103173677 6.4 6.4 0.0 1.0 100 -0.5 -0.5 0.0
IVS9nt6t>a
Sequence Walker  
a103173614t 103173564 55 103173619 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
IVS9nt-2a>c
Sequence Walker  
t103171158g 103171175 -18 103171157 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
IVS9nt-5t>a
Sequence Walker  
a103171161t 103171175 -18 103171157 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
IVS10nt3a>g
Sequence Walker  
t103171058c 103171061 -1 103171060 7.6 7.6 0.0 1.0 100 -0.3 -0.3 0.0
IVS10nt-11g>a
Sequence Walker  
c103170515t 103170535 -30 103170505 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
IVS10nt-11g>a
Sequence Walker  
c103170515t 103170466 39 103170505 2.1 2.1 0.0 1.0 100 -1.5 -1.5 0.0
IVS10nt-3c>t
Sequence Walker  
g103170507a 103170535 -30 103170505 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
IVS10nt-3c>t
Sequence Walker  
g103170507a 103170466 39 103170505 2.1 2.1 0.0 1.0 100 -1.5 -1.5 0.0
IVS10nt-3c>t
Sequence Walker  
g103170507a 103170460 45 103170505 0.4 0.4 0.0 1.0 100 -1.8 -1.8 0.0
IVS11nt-8g>a
Sequence Walker  
c103167248t 103167260 -19 103167241 3.2 3.2 0.0 1.0 100 -1.2 -1.2 0.0
IVS11nt-8g>a
Sequence Walker  
c103167248t 103167241 0 103167241 6.4 6.4 0.0 1.0 100 -0.5 -0.5 0.0
IVS11nt-8g>a
Sequence Walker  
c103167248t 103167206 35 103167241 6.9 6.9 0.0 1.0 100 -0.4 -0.4 0.0
IVS12nt2t>c
Sequence Walker  
a103167123g 103167085 39 103167124 4.3 4.3 0.0 1.0 100 -1.0 -1.0 0.0
IVS12nt2t>c
Sequence Walker  
a103167123g 103167076 48 103167124 0.3 0.3 0.0 1.0 100 -1.9 -1.9 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165976 -32 103165944 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165922 22 103165944 0.5 0.5 0.0 1.0 100 -1.8 -1.8 0.0
IVS12nt-5t>c
Sequence Walker  
a103165948g 103165912 32 103165944 7.2 7.2 0.0 1.0 100 -0.4 -0.4 0.0
IVS12nt-35c>t
Sequence Walker  
g103165978a 103166007 -63 103165944 2.4 2.4 0.0 1.0 100 -1.4 -1.4 0.0
IVS12nt-35c>t
Sequence Walker  
g103165978a 103165944 0 103165944 12.5 12.5 0.0 1.0 100 0.8 0.8 0.0