Gene: MTM1
mRNA Accession: U46024
Mutation:MTM1.txt
Chromosome: chr X

Sequence Walker  




c.2T>G


Instruction: t147532041g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147532026 -3 147532029 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0
Increased 147532039 10 147532029 -4.1 0.0 4.1 1.0 101.7 -3.7 -2.4 1.2



c.145G>T


Instruction: g147538027t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147537998 -20 147538018 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
No change 147538063 45 147538018 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0



c.205C>T


Instruction: c147538087t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147538063 -51 147538114 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
No change 147538114 0 147538114 10.6 10.6 0.0 1.0 100 0.8 0.8 0.0



c.535C>T


Instruction: c147580711t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147580665 -39 147580704 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0



c.614C>T


Instruction: c147580790t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147580783 -72 147580855 1.9 1.9 0.0 1.0 100 -1.9 -1.9 0.0
No change 147580818 -37 147580855 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0



c.679G>A


Instruction: g147585119a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147585152 34 147585118 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
No change 147585158 40 147585118 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
Decreased 147585119 1 147585118 2.0 -10.8 -12.8 -4.0 NA -1.8 -5.7 -3.9



c.683T>C


Instruction: t147585123c; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Decreased 147585119 1 147585118 2.0 2.0 -0.0 -1.0 97.9 -1.8 -1.8 -0.0
No change 147585152 34 147585118 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
No change 147585158 40 147585118 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
No change 147585168 50 147585118 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0



c.721C>T


Instruction: c147585161t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147585119 1 147585118 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
No change 147585152 34 147585118 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
Decreased 147585158 40 147585118 3.1 3.1 -0.0 -1.0 98.0 -1.5 -1.5 -0.0
No change 147585168 50 147585118 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
No change 147585183 65 147585118 4.8 4.8 0.0 1.0 100 -1.0 -1.0 0.0
No change 147585189 71 147585118 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0



c.836C>G


Instruction: c147585276g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147585287 -21 147585308 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
No change 147585308 0 147585308 12.6 12.6 0.0 1.0 100 1.4 1.4 0.0



c.1132G>A


Instruction: g147597335a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147597303 47 147597256 3.3 3.3 0.0 1.0 100 -1.4 -1.4 0.0
Decreased 147597330 74 147597256 1.3 1.0 -0.4 -1.3 77.5 -2.0 -2.1 -0.1



c.1172T>C


Instruction: t147597375c; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147597330 -134 147597464 1.3 1.3 0.0 1.0 100 -2.0 -2.0 0.0
No change 147597409 -55 147597464 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
No change 147597422 -42 147597464 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0



c.1190A>G


Instruction: a147597393g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147597409 -55 147597464 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
No change 147597422 -42 147597464 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0
Increased 147597393 -71 147597464 -10.8 2.0 12.8 4.1 410.2 -5.7 -1.8 3.9



c.1204G>A


Instruction: g147597407a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Increased 147597409 -55 147597464 1.1 3.4 2.3 4.9 489.0 -2.1 -1.4 0.7
No change 147597422 -42 147597464 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0



c.1262G>A


Instruction: g147599101a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599107 8 147599099 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
No change 147599113 14 147599099 4.5 4.5 0.0 1.0 100 -1.1 -1.1 0.0



c.109C>T


Instruction: c147535970t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147535998 0 147535998 9.4 9.4 0.0 1.0 100 0.4 0.4 0.0



c.142G>T


Instruction: g147538024t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147537975 -43 147538018 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
No change 147537998 -20 147538018 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
No change 147538063 45 147538018 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0



c.181G>T

Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z )Δ Z
Increased 147538058 40 147538018 -1.0 0.2 1.2 1.2 118.7 -2.7 -2.4 0.4
Increased 147538062 44 147538018 -5.3 2.9 8.2 7.7 766.7 -4.0 -1.5 2.5



c.1261C>T


Instruction: c147599100t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599107 8 147599099 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
No change 147599113 14 147599099 4.5 4.5 0.0 1.0 100 -1.1 -1.1 0.0
Increased 147599099 0 147599099 -5.3 2.1 7.5 4.4 439.3 -4.1 -1.8 2.3



c.1420C>T


Instruction: c147599873t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599880 -41 147599921 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
No change 147599898 -23 147599921 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
No change 147599921 0 147599921 11.8 11.8 0.0 1.0 100 1.2 1.2 0.0



c.1456C>T


Instruction: c147599909t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599880 -41 147599921 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
No change 147599898 -23 147599921 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
No change 147599921 0 147599921 11.8 11.8 0.0 1.0 100 1.2 1.2 0.0



c.63+2T>C


Instruction: t147532104c; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Decreased 147532103 0 147532103 9.8 2.3 -7.5 -177.5 0.5 0.5 -1.7 -2.3
No change 147532108 5 147532103 0.3 0.3 0.0 1.0 100 -2.3 -2.3 0.0



c.64-2A>G


Instruction: a147535923g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147535876 -48 147535924 4.0 4.0 0.0 1.0 100 -1.2 -1.2 0.0
No change 147535880 -44 147535924 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0
No change 147535886 -38 147535924 3.6 3.6 0.0 1.0 100 -1.4 -1.4 0.0



c.137-7T>G


Instruction: t147538012g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147537975 -43 147538018 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
No change 147537998 -20 147538018 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
Increased 147538012 -6 147538018 -6.5 1.3 7.8 2.5 246.0 -4.4 -2.0 2.4



c232-3C>A


Instruction: c147554022a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147554056 32 147554024 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0



c.232-2A>C


Instruction: a147554023c; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147554056 32 147554024 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0



c.528+1G>A


Instruction: g147578463a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147578415 -48 147578463 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0
No change 147578470 7 147578463 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
No change 147578488 25 147578463 7.9 7.9 0.0 1.0 100 -0.0 -0.0 0.0
No change 147578492 29 147578463 2.3 2.3 0.0 1.0 100 -1.7 -1.7 0.0
Decreased 147578459 -4 147578463 1.5 -2.0 -3.5 -2.9 NA -2.0 -3.0 -1.1
Decreased 147578463 0 147578463 10.6 -2.2 -12.8 -1568.3 NA 0.8 -3.1 -3.9



c.1261-10A>G


Instruction: a147599090g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599107 8 147599099 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
No change 147599113 14 147599099 4.5 4.5 0.0 1.0 100 -1.1 -1.1 0.0



c.1353+1G>A


Instruction: g147599193a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599170 -23 147599193 4.0 4.0 0.0 1.0 100 -1.2 -1.2 0.0
No change 147599172 -21 147599193 0.6 0.6 0.0 1.0 100 -2.3 -2.3 0.0
Decreased 147599193 0 147599193 11.5 -1.3 -12.8 -2922.7 NA 1.1 -2.8 -3.9



c.1467+1G>A


Instruction: g147599921a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147599880 -41 147599921 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
No change 147599898 -23 147599921 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
No change 147599967 46 147599921 6.2 6.2 0.0 1.0 100 -0.6 -0.6 0.0
Decreased 147599921 0 147599921 11.8 -1.0 -12.8 -3573.6 NA 1.2 -2.7 -3.9



c.106delC


Instruction: d147535967,147535967; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147535998 0 147535998 9.4 9.4 0.0 1.0 100 0.4 0.4 0.0



c.141-142insG


Instruction: i147538024,147538025g; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147537975 -43 147538018 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
No change 147537998 -20 147538018 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
No change 147538063 45 147538018 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
Increased 147538024 6 147538018 -4.8 0.8 5.5 1.7 171.9 -3.9 -2.2 1.7



c.465delT


Instruction: d147578399,147578399; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147578415 37 147578378 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0



c.469delG


Instruction: d147578403,147578403; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147578415 37 147578378 2.4 2.4 0.0 1.0 100 -1.7 -1.7 0.0



c.593-594insA


Instruction: i147580770,147580771a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147580783 79 147580704 1.9 1.9 0.0 1.0 100 -1.9 -1.9 0.0
No change 147580818 114 147580704 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0



c.445-1insGAAA


Instruction: i147532040,147532041gaaa; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147532026 -3 147532029 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0



c.601delT


Instruction: d147580777,147580777; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147580783 79 147580704 1.9 1.9 0.0 1.0 100 -1.9 -1.9 0.0
No change 147580818 114 147580704 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0



c.969insA


Instruction: i147589253,147589254a; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147589254 -84 147589338 4.8 4.8 0.0 1.0 100 -1.0 -1.0 0.0
No change 147589278 -60 147589338 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0



c.1015insT


Instruction: i147589299,147589300t; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147589254 -84 147589338 4.8 4.8 0.0 1.0 100 -1.0 -1.0 0.0
No change 147589278 -60 147589338 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
No change 147589322 -16 147589338 2.9 2.9 0.0 1.0 100 -1.5 -1.5 0.0
No change 147589338 0 147589338 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0
No change 147589342 4 147589338 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0



c.1789delC


Instruction: d147611008,147611008; Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
No change 147611014 151 147610863 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0

Legend:    Site Abolished   Leaky Site   Cryptic Site created   Strengthened Pre-existing site   Pre-existing Site   Weakened Pre-existing Site