Gene: LIS1
mRNA Accession: L13386
Mutation:LIS1.txt
Chromosome: chr 17

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
484G>A
Sequence Walker  
g2524351a 2524352 -84 2524436 0.1 -2.9 -3.1 -1.1 NA -2.4 -3.3 -0.9
771-772delTG
Sequence Walker  
d2527392,2527393 2527386 -777 2528163 0.8 -0.1 -0.9 -1.7 NA -2.2 -2.5 -0.3
805delA
Sequence Walker  
d2528297,2528297 2528295 -98 2528393 0.4 -2.7 -3.1 -1.3 NA -2.3 -3.3 -0.9
c.1002+1G>A
Sequence Walker  
g2530711a 2530711 0 2530711 6.0 -6.8 -12.8 -65.6 NA -0.6 -4.5 -3.9
c.1002+5G>A
Sequence Walker
g2530715a 2530711 0 2530711 6.0 2.5 -3.5 -11.5 8.7 -0.6 -1.7 -1.1
c.1159+3insCA
Sequence Walker  
i2492395,2492396ca 2492396 -29 2492425 1.3 -12.6 -13.9 -2.5 NA -2.0 -6.3 -4.2
c.900+1G>A
Sequence Walker  
g2528393a 2528393 0 2528393 2.8 -10.0 -12.8 -7.1 NA -1.6 -5.5 -3.9