Gene: LIS1
mRNA Accession: L13386
Chromosome: chr 17

Sequence Walker  




92T>C


Instruction: t2519535c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2519580 192519561 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 2519587 262519561 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
Sites found for donor
No Change 2519561 02519561 5.8 5.8 0.0 1.0100 -0.7 -0.7 0.0



446A>G


Instruction: a2524313g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Increased 2524329 632524266 0.7 0.8 0.0 1.0103.1 -1.8 -1.8 0.0
No Change 2524349 832524266 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
Sites found for donor
No Change 2524267 12524266 8.4 8.4 0.0 1.0100 0.1 0.1 0.0
No Change 2524269 32524266 0.9 0.9 0.0 1.0100 -2.2 -2.2 0.0
No Change 2524352 862524266 0.1 0.1 0.0 1.0100 -2.4 -2.4 0.0



484G>A


Instruction: g2524351a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2524329 -1072524436 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
Increased 2524349 -872524436 3.5 3.6 0.0 1.0103.1 -1.2 -1.2 0.0
No Change 2524378 -582524436 11.8 11.8 0.0 1.0100 0.6 0.6 0.0
increased2524352-842524436 -6.3 1.9 8.2 3.6364.3 -3.3 -1.5 1.8
Sites found for donor
Decreased2524352-842524436 0.1 -2.9 -3.1 -1.1NA -2.4 -3.3 -0.9



499T>C


Instruction: t2524366c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2524349 -872524436 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
Decreased2524378 -58 2524436 11.8 11.4 -0.4 -1.375.9 0.6 0.6 -0.1
No Change 2524407 -292524436 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
Sites found for donor
No Change 2524352 -842524436 0.1 0.1 0.0 1.0100 -2.4 -2.4 0.0



949G>C


Instruction: g2530657c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased2530655 47 2530608 4.4 4.0 -0.4 -1.374.5 -1.0 -1.1 -0.1
Decreased2530657492530608 0.9 -6.4 -7.3 -1.8NA -1.8 -3.3 -1.6
Sites found for donor
No Change 2530619 112530608 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 2530622 142530608 4.3 4.3 0.0 1.0100 -1.1 -1.1 0.0
No Change 2530674 662530608 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 2530681 732530608 3.5 3.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 2530691 832530608 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 2530695 872530608 1.5 1.5 0.0 1.0100 -2.0 -2.0 0.0



265C>T


Instruction: c2521168t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2521164 692521095 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 2521201 1062521095 3.2 3.2 0.0 1.0100 -1.2 -1.2 0.0
Sites found for donor
No Change 2521143 482521095 0.5 0.5 0.0 1.0100 -2.3 -2.3 0.0
No Change 2521148 532521095 4.6 4.6 0.0 1.0100 -1.0 -1.0 0.0
No Change 2521160 652521095 2.6 2.6 0.0 1.0100 -1.6 -1.6 0.0



430C>T


Instruction: c2524297t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2524329 632524266 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 2524349 832524266 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
Sites found for donor
No Change 2524267 12524266 8.4 8.4 0.0 1.0100 0.1 0.1 0.0
No Change 2524269 32524266 0.9 0.9 0.0 1.0100 -2.2 -2.2 0.0



817C>T


Instruction: c2528309t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2528351 -422528393 4.2 4.2 0.0 1.0100 -1.0 -1.0 0.0
Sites found for donor
No Change 2528264 -1292528393 4.2 4.2 0.0 1.0100 -1.2 -1.2 0.0
No Change 2528270 -1232528393 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 2528291 -1022528393 0.3 0.3 0.0 1.0100 -2.4 -2.4 0.0
No Change 2528295 -982528393 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 2528324 -692528393 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2528327 -662528393 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0



866C>G


Instruction: c2528358g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2528351 -422528393 4.2 4.2 0.0 1.0100 -1.0 -1.0 0.0
Decreased2528378 -15 2528393 5.6 4.6 -1.0 -2.049.2 -0.7 -0.9 -0.2
No Change 2528384 -92528393 4.7 4.7 0.0 1.0100 -0.9 -0.9 0.0
Decreased2528375-182528393 0.2 -1.1 -1.3 -1.1NA -1.9 -2.2 -0.3
Sites found for donor
No Change 2528324 -692528393 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2528327 -662528393 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
No Change 2528393 02528393 2.8 2.8 0.0 1.0100 -1.6 -1.6 0.0
No Change 2528398 52528393 0.6 0.6 0.0 1.0100 -2.2 -2.2 0.0



154-155insA


Instruction: i2519965,2519966a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2519941 -1782520119 2.3 2.3 0.0 1.0100 -1.4 -1.4 0.0
No Change 2519959 -1602520119 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
Decreased2519969 -150 2520119 2.8 2.3 -0.5 -1.469.8 -1.3 -1.4 -0.1
Decreased2519983 -136 2520119 2.6 2.0 -0.6 -1.565.6 -1.4 -1.5 -0.1
Decreased2519967-1522520119 0.3 0.3 0.0 1.0103.1 -1.9 -1.9 0.0
increased2519966-1532520119 -7.5 0.3 7.8 1.3125.3 -3.6 -1.9 1.7
Sites found for donor
No Change 2519942 -1772520119 6.8 6.8 0.0 1.0100 -0.4 -0.4 0.0
No Change 2519969 -1502520119 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2519984 -1352520119 10.7 10.7 0.0 1.0100 0.8 0.8 0.0



162-163insA


Instruction: i2519957,2519958a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2519934 -1852520119 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 2519941 -1782520119 2.3 2.3 0.0 1.0100 -1.4 -1.4 0.0
Decreased2519959 -160 2520119 1.7 1.6 -0.1 -1.191.7 -1.6 -1.6 -0.0
Decreased2519969 -150 2520119 2.8 2.0 -0.9 -1.854.6 -1.3 -1.5 -0.2
No Change 2519983 -1362520119 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
Decreased2519967-1522520119 0.3 -8.9 -9.1 -1.2NA -1.9 -3.9 -2.0
Sites found for donor
No Change 2519908 -2112520119 0.7 0.7 0.0 1.0100 -2.2 -2.2 0.0
No Change 2519942 -1772520119 6.8 6.8 0.0 1.0100 -0.4 -0.4 0.0
No Change 2519969 -1502520119 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2519984 -1352520119 10.7 10.7 0.0 1.0100 0.8 0.8 0.0



162delA


Instruction: d2520164,2520164 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor
No Change 2520140 -552520195 4.5 4.5 0.0 1.0100 -1.1 -1.1 0.0
No Change 2520195 02520195 8.6 8.6 0.0 1.0100 0.2 0.2 0.0



166delA


Instruction: d2520168,2520168 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2520217 222520195 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 2520219 242520195 0.0 0.0 0.0 1.0100 -1.9 -1.9 0.0
Sites found for donor
No Change 2520140 -552520195 4.5 4.5 0.0 1.0100 -1.1 -1.1 0.0
No Change 2520195 02520195 8.6 8.6 0.0 1.0100 0.2 0.2 0.0



703-704delGA


Instruction: d2527460,2527461 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2527434 -7292528163 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
No Change 2527495 -6682528163 2.5 2.5 0.0 1.0100 -1.4 -1.4 0.0
Sites found for donor
No Change 2527420 -7432528163 4.9 4.9 0.0 1.0100 -1.0 -1.0 0.0
No Change 2527431 -7322528163 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 2527447 -7162528163 0.9 0.9 0.0 1.0100 -2.2 -2.2 0.0
No Change 2527449 -7142528163 3.5 3.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 2527473 -6902528163 2.4 2.4 0.0 1.0100 -1.7 -1.7 0.0
No Change 2527486 -6772528163 1.8 1.8 0.0 1.0100 -1.9 -1.9 0.0



771-772delTG


Instruction: d2527392,2527393 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2527419 -7442528163 11.8 11.8 0.0 1.0100 0.6 0.6 0.0
No Change 2527434 -7292528163 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
Sites found for donor
No Change 2527348 -8152528163 5.9 5.9 0.0 1.0100 -0.6 -0.6 0.0
No Change 2527353 -8102528163 2.6 2.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 2527420 -7432528163 4.9 4.9 0.0 1.0100 -1.0 -1.0 0.0
No Change 2527431 -7322528163 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
Decreased2527386-7772528163 0.8 -0.1 -0.9 -1.7NA -2.2 -2.5 -0.3
increased2527391-7722528163 -12.9 0.3 13.2 1.2123.8 -6.4 -2.3 4.0



805delA


Instruction: d2528297,2528297 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor
No Change 2528264 -1292528393 4.2 4.2 0.0 1.0100 -1.2 -1.2 0.0
No Change 2528270 -1232528393 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 2528291 -1022528393 0.3 0.3 0.0 1.0100 -2.4 -2.4 0.0
No Change 2528324 -692528393 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2528327 -662528393 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
Decreased2528295-982528393 0.4 -2.7 -3.1 -1.3NA -2.3 -3.3 -0.9



881-882delCT


Instruction: d2527282,2527283 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2527332 -8312528163 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
Sites found for donor
No Change 2527233 -9302528163 1.8 1.8 0.0 1.0100 -1.9 -1.9 0.0



903-904insT


Instruction: i2529705,2529706t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2529733 -8752530608 5.6 5.6 0.0 1.0100 -0.7 -0.7 0.0
No Change 2529755 -8532530608 4.8 4.8 0.0 1.0100 -0.9 -0.9 0.0
No Change 2529756 -8522530608 3.4 3.4 0.0 1.0100 -1.2 -1.2 0.0
No Change 2529757 -8512530608 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
Sites found for donor
No Change 2529665 -9432530608 0.6 0.6 0.0 1.0100 -2.3 -2.3 0.0
No Change 2529675 -9332530608 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0



1018-1019insT


Instruction: i2533249,2533250t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Increased 2533256 -10112534267 2.6 3.6 1.1 2.1207.1 -1.4 -1.1 0.2
Increased 2533268 -9992534267 1.8 2.4 0.5 1.5146.2 -1.5 -1.4 0.1
increased2533260-10072534267 -0.7 0.6 1.3 1.5153.9 -2.1 -1.8 0.3
Sites found for donor
No Change 2533207 -10602534267 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 2533240 -10272534267 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2533257 -10102534267 5.5 5.5 0.0 1.0100 -0.8 -0.8 0.0
No Change 2533288 -9792534267 6.8 6.8 0.0 1.0100 -0.4 -0.4 0.0
No Change 2533292 -9752534267 1.9 1.9 0.0 1.0100 -1.9 -1.9 0.0



1050-1051insG


Instruction: i2533217,2533218g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2533206 -10612534267 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 2533212 -10552534267 8.9 8.9 0.0 1.0100 0.0 0.0 0.0
No Change 2533256 -10112534267 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
No Change 2533268 -9992534267 1.8 1.8 0.0 1.0100 -1.5 -1.5 0.0
Sites found for donor
increasednewly inserted = 2533218-10492534267 0.0 3.1 3.1 8.4842.3 0.0 -1.5 -1.5
No Change 2533207 -10602534267 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 2533240 -10272534267 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 2533257 -10102534267 5.5 5.5 0.0 1.0100 -0.8 -0.8 0.0



c.569-10T>C


Instruction: t2526749c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased2526758 0 2526758 5.9 5.3 -0.6 -1.566.7 -0.6 -0.8 -0.1
No Change 2526782 242526758 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 2526785 272526758 3.6 3.6 0.0 1.0100 -1.2 -1.2 0.0
Sites found for donor
No Change 2526717 -412526758 0.0 0.0 0.0 1.0100 -2.4 -2.4 0.0
No Change 2526720 -382526758 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
Increased 2526746 -122526758 0.1 0.1 0.0 1.0102.0 -2.4 -2.4 0.0



c.900+1G>A


Instruction: g2528393a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2528375 -182528393 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 2528378 -152528393 5.6 5.6 0.0 1.0100 -0.7 -0.7 0.0
No Change 2528384 -92528393 4.7 4.7 0.0 1.0100 -0.9 -0.9 0.0
No Change 2528430 372528393 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 2528440 472528393 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
Sites found for donor
No Change 2528398 52528393 0.6 0.6 0.0 1.0100 -2.2 -2.2 0.0
Decreased252839302528393 2.8 -10.0 -12.8 -7.1NA -1.6 -5.5 -3.9



c.1002+1G>A


Instruction: g2530711a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2530744 332530711 2.7 2.7 0.0 1.0100 -1.3 -1.3 0.0
No Change 2530750 392530711 4.3 4.3 0.0 1.0100 -1.0 -1.0 0.0
No Change 2530752 412530711 3.6 3.6 0.0 1.0100 -1.1 -1.1 0.0
No Change 2530759 482530711 1.3 1.3 0.0 1.0100 -1.6 -1.6 0.0
Sites found for donor
No Change 2530674 -372530711 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 2530681 -302530711 3.5 3.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 2530691 -202530711 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 2530695 -162530711 1.5 1.5 0.0 1.0100 -2.0 -2.0 0.0
Decreased253071102530711 6.0 -6.8 -12.8 -65.6NA -0.6 -4.5 -3.9



c.1002+5G>A


Instruction: g2530715a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2530744 332530711 2.7 2.7 0.0 1.0100 -1.3 -1.3 0.0
No Change 2530750 392530711 4.3 4.3 0.0 1.0100 -1.0 -1.0 0.0
No Change 2530752 412530711 3.6 3.6 0.0 1.0100 -1.1 -1.1 0.0
No Change 2530759 482530711 1.3 1.3 0.0 1.0100 -1.6 -1.6 0.0
No Change 2530766 552530711 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
No Change 2530767 562530711 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
Sites found for donor
No Change 2530674 -372530711 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 2530681 -302530711 3.5 3.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 2530691 -202530711 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 2530695 -162530711 1.5 1.5 0.0 1.0100 -2.0 -2.0 0.0
Decreased2530711 0 2530711 6.0 2.5 -3.5 -11.58.7 -0.6 -1.7 -1.1



c.1159+3insCA


Instruction: i2492395,2492396ca ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2492387 -382492425 1.8 1.8 0.0 1.0100 -1.6 -1.6 0.0
Decreased2492407 -18 2492425 1.8 0.9 -0.9 -1.854.7 -1.6 -1.7 -0.2
Sites found for donor
No Change 2492348 -772492425 0.0 0.0 0.0 1.0100 -2.4 -2.4 0.0
No Change 2492425 02492425 6.7 6.7 0.0 1.0100 -0.4 -0.4 0.0
Decreased2492396-292492425 1.3 -12.6 -13.9 -2.5NA -2.0 -6.3 -4.2



c.568+27T>C


Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Unprocessed due to the following error. c.568+27T>C the old base at 2524462 is NOT t! It is c.



687A>T


Instruction: a2528179t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2528163 02528163 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
Increased 2528186 232528163 0.6 2.5 2.0 3.9391.8 -1.8 -1.4 0.4
Sites found for donor
No Change 2528140 -232528163 6.4 6.4 0.0 1.0100 -0.5 -0.5 0.0
No Change 2528169 62528163 2.2 2.2 0.0 1.0100 -1.8 -1.8 0.0
No Change 2528171 82528163 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
No Change 2528201 382528163 5.8 5.8 0.0 1.0100 -0.7 -0.7 0.0
No Change 2528205 422528163 2.2 2.2 0.0 1.0100 -1.8 -1.8 0.0
No Change 2528210 472528163 6.0 6.0 0.0 1.0100 -0.6 -0.6 0.0



1188C>T


Instruction: c2535861t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 2535832 02535832 14.4 14.4 0.0 1.0100 1.2 1.2 0.0
No Change 2535840 82535832 4.6 4.6 0.0 1.0100 -0.9 -0.9 0.0
No Change 2535842 102535832 4.2 4.2 0.0 1.0100 -1.0 -1.0 0.0
No Change 2535843 112535832 3.9 3.9 0.0 1.0100 -1.1 -1.1 0.0
Increased 2535869 372535832 3.5 3.8 0.3 1.2124.6 -1.2 -1.1 0.1
Increased 2535874 422535832 1.9 2.4 0.4 1.3134.9 -1.5 -1.4 0.1
Sites found for donor
No Change 2535883 512535832 2.8 2.8 0.0 1.0100 -1.6 -1.6 0.0
No Change 2535889 572535832 5.2 5.2 0.0 1.0100 -0.9 -0.9 0.0
No Change 2535891 592535832 2.8 2.8 0.0 1.0100 -1.6 -1.6 0.0



1236T>G


Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Unprocessed due to the following error. 1236T>G the old base at 2535909 is NOT t! It is g.



1250C>T


Instruction: c2535923t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor