Gene: LIS1
mRNA Accession: L13386
Mutation:LIS1.txt
Chromosome: chr 17

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1050-1051insG
Sequence Walker  
i2533217,2533218g 2533206 -1061 2534267 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
1050-1051insG
Sequence Walker  
i2533217,2533218g 2533212 -1055 2534267 8.9 8.9 0.0 1.0 100 0.0 0.0 0.0
1050-1051insG
Sequence Walker  
i2533217,2533218g 2533256 -1011 2534267 2.6 2.6 0.0 1.0 100 -1.4 -1.4 0.0
1050-1051insG
Sequence Walker  
i2533217,2533218g 2533268 -999 2534267 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
1188C>T
Sequence Walker  
c2535861t 2535832 0 2535832 14.4 14.4 0.0 1.0 100 1.2 1.2 0.0
1188C>T
Sequence Walker  
c2535861t 2535840 8 2535832 4.6 4.6 0.0 1.0 100 -0.9 -0.9 0.0
1188C>T
Sequence Walker  
c2535861t 2535842 10 2535832 4.2 4.2 0.0 1.0 100 -1.0 -1.0 0.0
1188C>T
Sequence Walker  
c2535861t 2535843 11 2535832 3.9 3.9 0.0 1.0 100 -1.1 -1.1 0.0
154-155insA
Sequence Walker  
i2519965,2519966a 2519941 -178 2520119 2.3 2.3 0.0 1.0 100 -1.4 -1.4 0.0
154-155insA
Sequence Walker  
i2519965,2519966a 2519959 -160 2520119 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
162-163insA
Sequence Walker  
i2519957,2519958a 2519934 -185 2520119 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
162-163insA
Sequence Walker  
i2519957,2519958a 2519941 -178 2520119 2.3 2.3 0.0 1.0 100 -1.4 -1.4 0.0
162-163insA
Sequence Walker  
i2519957,2519958a 2519983 -136 2520119 2.6 2.6 0.0 1.0 100 -1.4 -1.4 0.0
166delA
Sequence Walker  
d2520168,2520168 2520217 22 2520195 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
166delA
Sequence Walker  
d2520168,2520168 2520219 24 2520195 0.0 0.0 0.0 1.0 100 -1.9 -1.9 0.0
265C>T
Sequence Walker  
c2521168t 2521164 69 2521095 0.3 0.3 0.0 1.0 100 -1.9 -1.9 0.0
265C>T
Sequence Walker  
c2521168t 2521201 106 2521095 3.2 3.2 0.0 1.0 100 -1.2 -1.2 0.0
430C>T
Sequence Walker  
c2524297t 2524329 63 2524266 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
430C>T
Sequence Walker  
c2524297t 2524349 83 2524266 3.5 3.5 0.0 1.0 100 -1.2 -1.2 0.0
446A>G
Sequence Walker  
a2524313g 2524349 83 2524266 3.5 3.5 0.0 1.0 100 -1.2 -1.2 0.0
484G>A
Sequence Walker  
g2524351a 2524329 -107 2524436 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
484G>A
Sequence Walker  
g2524351a 2524378 -58 2524436 11.8 11.8 0.0 1.0 100 0.6 0.6 0.0
499T>C
Sequence Walker  
t2524366c 2524349 -87 2524436 3.5 3.5 0.0 1.0 100 -1.2 -1.2 0.0
499T>C
Sequence Walker  
t2524366c 2524407 -29 2524436 2.6 2.6 0.0 1.0 100 -1.4 -1.4 0.0
687A>T
Sequence Walker  
a2528179t 2528163 0 2528163 3.5 3.5 0.0 1.0 100 -1.2 -1.2 0.0
703-704delGA
Sequence Walker  
d2527460,2527461 2527434 -729 2528163 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
703-704delGA
Sequence Walker  
d2527460,2527461 2527495 -668 2528163 2.5 2.5 0.0 1.0 100 -1.4 -1.4 0.0
771-772delTG
Sequence Walker  
d2527392,2527393 2527419 -744 2528163 11.8 11.8 0.0 1.0 100 0.6 0.6 0.0
771-772delTG
Sequence Walker  
d2527392,2527393 2527434 -729 2528163 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
817C>T
Sequence Walker  
c2528309t 2528351 -42 2528393 4.2 4.2 0.0 1.0 100 -1.0 -1.0 0.0
866C>G
Sequence Walker  
c2528358g 2528351 -42 2528393 4.2 4.2 0.0 1.0 100 -1.0 -1.0 0.0
866C>G
Sequence Walker  
c2528358g 2528384 -9 2528393 4.7 4.7 0.0 1.0 100 -0.9 -0.9 0.0
881-882delCT
Sequence Walker  
d2527282,2527283 2527332 -831 2528163 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
903-904insT
Sequence Walker  
i2529705,2529706t 2529733 -875 2530608 5.6 5.6 0.0 1.0 100 -0.7 -0.7 0.0
903-904insT
Sequence Walker  
i2529705,2529706t 2529755 -853 2530608 4.8 4.8 0.0 1.0 100 -0.9 -0.9 0.0
903-904insT
Sequence Walker  
i2529705,2529706t 2529756 -852 2530608 3.4 3.4 0.0 1.0 100 -1.2 -1.2 0.0
903-904insT
Sequence Walker  
i2529705,2529706t 2529757 -851 2530608 2.6 2.6 0.0 1.0 100 -1.4 -1.4 0.0
92T>C
Sequence Walker  
t2519535c 2519580 19 2519561 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
92T>C
Sequence Walker  
t2519535c 2519587 26 2519561 3.1 3.1 0.0 1.0 100 -1.3 -1.3 0.0
c.1002+1G>A
Sequence Walker  
g2530711a 2530744 33 2530711 2.7 2.7 0.0 1.0 100 -1.3 -1.3 0.0
c.1002+1G>A
Sequence Walker  
g2530711a 2530750 39 2530711 4.3 4.3 0.0 1.0 100 -1.0 -1.0 0.0
c.1002+1G>A
Sequence Walker  
g2530711a 2530752 41 2530711 3.6 3.6 0.0 1.0 100 -1.1 -1.1 0.0
c.1002+1G>A
Sequence Walker  
g2530711a 2530759 48 2530711 1.3 1.3 0.0 1.0 100 -1.6 -1.6 0.0
c.1002+5G>A
Sequence Walker  
g2530715a 2530744 33 2530711 2.7 2.7 0.0 1.0 100 -1.3 -1.3 0.0
c.1002+5G>A
Sequence Walker  
g2530715a 2530750 39 2530711 4.3 4.3 0.0 1.0 100 -1.0 -1.0 0.0
c.1002+5G>A
Sequence Walker  
g2530715a 2530752 41 2530711 3.6 3.6 0.0 1.0 100 -1.1 -1.1 0.0
c.1002+5G>A
Sequence Walker  
g2530715a 2530759 48 2530711 1.3 1.3 0.0 1.0 100 -1.6 -1.6 0.0
c.1002+5G>A
Sequence Walker  
g2530715a 2530766 55 2530711 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
c.1002+5G>A
Sequence Walker  
g2530715a 2530767 56 2530711 1.5 1.5 0.0 1.0 100 -1.6 -1.6 0.0
c.1159+3insCA
Sequence Walker  
i2492395,2492396ca 2492387 -38 2492425 1.8 1.8 0.0 1.0 100 -1.6 -1.6 0.0
c.569-10T>C
Sequence Walker  
t2526749c 2526782 24 2526758 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
c.569-10T>C
Sequence Walker  
t2526749c 2526785 27 2526758 3.6 3.6 0.0 1.0 100 -1.2 -1.2 0.0
c.900+1G>A
Sequence Walker  
g2528393a 2528375 -18 2528393 0.2 0.2 0.0 1.0 100 -1.9 -1.9 0.0
c.900+1G>A
Sequence Walker  
g2528393a 2528378 -15 2528393 5.6 5.6 0.0 1.0 100 -0.7 -0.7 0.0
c.900+1G>A
Sequence Walker  
g2528393a 2528384 -9 2528393 4.7 4.7 0.0 1.0 100 -0.9 -0.9 0.0
c.900+1G>A
Sequence Walker  
g2528393a 2528430 37 2528393 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
c.900+1G>A
Sequence Walker  
g2528393a 2528440 47 2528393 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0