Gene: DTD
mRNA Accession: U14528
Mutation:DTD.txt
Chromosome: chr 5

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1184C>T
Sequence Walker
c149343498t 149343520 507 149343013 2.5 2.5 -0.0 -1.0 96.5 -1.4 -1.4 -0.0
1269-1272delAAAC
Sequence Walker
d149341742,149341745 149341770 -1243 149343013 0.4 0.1 -0.3 -1.2 80.0 -1.8 -1.9 -0.1
1421delT
Sequence Walker
d149343735,149343735 149343751 738 149343013 5.5 5.0 -0.4 -1.3 74.3 -0.7 -0.8 -0.1
1421delT
Sequence Walker
d149343735,149343735 149343752 739 149343013 1.9 1.5 -0.3 -1.3 79.3 -1.5 -1.6 -0.1
1421delT
Sequence Walker
d149343735,149343735 149343753 740 149343013 1.2 0.5 -0.7 -1.6 60.9 -1.7 -1.8 -0.2
1421delT
Sequence Walker
d149343735,149343735 149343756 743 149343013 2.0 1.9 -0.1 -1.1 91.0 -1.5 -1.5 -0.0
1478G>A
Sequence Walker
g149343792a 149343810 797 149343013 0.7 0.5 -0.2 -1.2 86.5 -1.8 -1.8 -0.0
1751delA
Sequence Walker
d149344065,149344065 149344081 1068 149343013 0.5 0.3 -0.2 -1.2 86.5 -1.8 -1.9 -0.0
1751delA
Sequence Walker  
d149344065,149344065 149344067 1054 149343013 5.3 -12.7 -18.0 -39.7 NA -0.8 -4.7 -3.9
1751delA
Sequence Walker  
d149344065,149344065 149344078 1065 149343013 0.3 -11.3 -11.5 -1.2 NA -1.9 -4.4 -2.5
282delC
Sequence Walker
d149340655,149340655 149340664 318 149340346 12.1 11.4 -0.7 -1.7 59.8 0.7 0.5 -0.2
282delC
Sequence Walker  
d149340655,149340655 149340656 310 149340346 1.1 -8.4 -9.5 -2.2 NA -1.7 -3.8 -2.1
282delC
Sequence Walker  
d149340655,149340655 149340661 315 149340346 0.1 -6.4 -6.5 -1.1 NA -1.9 -3.3 -1.4
422T>C
Sequence Walker
t149340795c 149340816 -257 149341073 7.8 7.7 -0.1 -1.0 96.1 -0.2 -0.3 -0.0
476delT
Sequence Walker
d149340849,149340849 149340872 -201 149341073 0.6 0.1 -0.5 -1.4 71.4 -1.8 -1.9 -0.1
476delT
Sequence Walker  
d149340849,149340849 149340850 -223 149341073 0.3 -9.6 -9.9 -1.2 NA -1.9 -4.0 -2.2
558C>T
Sequence Walker
c149340931t 149340956 -117 149341073 7.5 7.5 -0.0 -1.0 98.4 -0.3 -0.3 -0.0
731-737delGATGGGC
Sequence Walker
d149342277,149342283 149342287 -726 149343013 2.6 1.1 -1.4 -2.7 36.6 -1.4 -1.7 -0.3
IVS1+2T>C
Sequence Walker
t149341074c 149341072 -1 149341073 3.0 2.1 -0.9 -1.9 52.2 -1.3 -1.5 -0.2