Gene: DHCR7
mRNA Accession: AF034544
Mutation:DHCR7.txt
Chromosome: chr 11

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
321G>C
Sequence Walker
c71377737g 71377736 0 71377736 6.5 2.5 -4.0 -16.5 6.0 -0.5 -1.7 -1.2
326T>C
Sequence Walker
a71376093g 71376097 1 71376098 5.1 5.1 -0.0 -1.0 97.9 -0.9 -0.9 -0.0
546G>C
Sequence Walker  
c71375051g 71375051 -81 71374970 4.4 -5.5 -9.8 -20.4 NA -1.1 -4.1 -3.0
841G>A
Sequence Walker  
c71371678t 71371678 10 71371688 3.2 -9.6 -12.8 -9.0 NA -1.5 -5.4 -3.9
906C>G
Sequence Walker
g71371613c 71371610 -55 71371555 1.8 0.6 -1.2 -2.2 44.7 -1.9 -2.3 -0.4
932G>A
Sequence Walker  
c71371587t 71371587 -32 71371555 0.2 -12.6 -12.8 -1.1 NA -2.4 -6.3 -3.9
970T>C
Sequence Walker
a71369577g 71369582 2 71369584 2.4 1.0 -1.4 -2.7 37.4 -1.7 -2.1 -0.4
976G>T
Sequence Walker  
c71369571a 71369571 13 71369584 0.4 -7.4 -7.8 -1.3 NA -2.3 -4.7 -2.4
1054C>T
Sequence Walker
g71369493a 71369490 94 71369584 2.1 0.5 -1.6 -3.0 32.9 -1.8 -2.3 -0.5
1058T>C
Sequence Walker  
a71369489g 71369490 94 71369584 2.1 -5.4 -7.5 -4.3 NA -1.8 -4.1 -2.3