Gene: DHCR7
mRNA Accession: AF034544
Mutation:DHCR7.txt
Chromosome: chr 11

Sequence Walker  


Information Increased
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
762insT
Sequence Walker  
i71372691,71372692a 71372685 -63 71372622 8.1 9.7 1.6 3.0 295.5 -0.2 0.2 0.3
762insT
Sequence Walker  
i71372691,71372692a 71372680 -58 71372622 1.7 2.3 0.6 1.5 148.5 -1.6 -1.4 0.1
IVS8-1G>C
Sequence Walker  
c71369584g 71369583 1 71369584 1.4 2.1 0.7 1.7 166.6 -1.6 -1.5 0.2
IVS8-1G>C
Sequence Walker  
c71369584g 71369582 2 71369584 -4.0 2.0 6.0 3.9 388.0 -2.8 -1.5 1.3
151C>T
Sequence Walker  
g71377907a 71377900 60 71377960 1.2 1.2 0.0 1.0 102.7 -1.7 -1.7 0.0
151C>T
Sequence Walker  
g71377907a 71377898 62 71377960 0.8 1.4 0.6 1.5 149.8 -1.8 -1.6 0.1
296T>C
Sequence Walker  
a71377762g 71377737 -1 71377736 9.6 9.6 0.0 1.0 101.5 0.2 0.2 0.0
321G>C
Sequence Walker  
c71377737g 71377732 4 71377736 1.4 4.1 2.7 6.3 628.1 -1.6 -1.0 0.6
321G>C
Sequence Walker  
c71377737g 71377729 7 71377736 1.1 2.7 1.6 3.0 303.6 -1.7 -1.4 0.4
356A>T
Sequence Walker  
t71376063a 71376060 38 71376098 1.7 1.8 0.1 1.0 104.3 -1.6 -1.6 0.0
356A>T
Sequence Walker  
t71376063a 71376059 39 71376098 3.3 6.2 2.8 7.2 719.6 -1.2 -0.6 0.6
356A>T
Sequence Walker  
t71376063a 71376040 58 71376098 4.6 5.3 0.6 1.6 155.3 -0.9 -0.8 0.1
461C>T
Sequence Walker  
g71375136a 71375116 69 71375185 1.8 2.0 0.2 1.1 111.8 -1.5 -1.5 0.0
461C>G
Sequence Walker  
g71375136c 71375136 49 71375185 -3.1 4.2 7.3 18.0 1800.0 -2.6 -1.0 1.6
506C>T
Sequence Walker  
g71375091a 71375085 100 71375185 0.7 0.8 0.2 1.1 111.1 -1.8 -1.8 0.0
506C>T
Sequence Walker  
g71375091a 71375082 103 71375185 -0.4 0.1 0.6 1.1 110.5 -2.0 -1.9 0.1
523G>C
Sequence Walker  
c71375074g 71375072 -102 71374970 -5.1 0.8 6.0 1.8 179.3 -3.1 -1.8 1.3
523G>C
Sequence Walker  
c71375074g 71375070 -100 71374970 -1.6 0.9 2.5 1.9 187.9 -2.3 -1.7 0.6
523G>C
Sequence Walker  
c71375074g 71375067 -97 71374970 -1.0 0.9 1.9 1.9 186.8 -2.2 -1.7 0.4
730G>A
Sequence Walker  
c71372724t 71372723 -101 71372622 -4.9 3.2 8.2 9.5 949.8 -3.0 -1.2 1.8
744G>T
Sequence Walker  
c71372710a 71372685 -63 71372622 8.1 9.0 0.9 1.9 185.5 -0.2 0.0 0.2
852C>A
Sequence Walker  
g71371667t 71371657 31 71371688 -6.2 1.2 7.4 2.3 229.9 -3.3 -1.7 1.6
932G>A
Sequence Walker  
c71371587t 71371563 -8 71371555 3.3 3.7 0.4 1.3 130.5 -1.2 -1.1 0.1
932G>A
Sequence Walker  
c71371587t 71371565 -10 71371555 -0.4 0.1 0.4 1.0 104.2 -2.0 -1.9 0.1
957G>A
Sequence Walker  
c71371562t 71371556 -1 71371555 8.0 8.1 0.1 1.0 104.4 -0.2 -0.2 0.0
976G>T
Sequence Walker  
c71369571a 71369554 30 71369584 4.3 5.8 1.5 2.9 292.3 -1.0 -0.7 0.3
986C>T
Sequence Walker  
g71369561a 71369554 30 71369584 4.3 4.3 0.0 1.0 102.7 -1.0 -1.0 0.0
1054C>T
Sequence Walker  
g71369493a 71369476 108 71369584 1.6 1.9 0.2 1.2 118.1 -1.6 -1.5 0.1
1055G>A
Sequence Walker  
c71369492t 71369491 93 71369584 -2.3 5.8 8.2 57.3 5731.9 -2.4 -0.7 1.8
1139G>A
Sequence Walker  
c71369408t 71369383 201 71369584 0.7 1.3 0.6 1.5 148.5 -1.8 -1.7 0.1
1139G>C
Sequence Walker  
c71369408g 71369383 201 71369584 0.7 1.6 0.9 1.9 188.4 -1.8 -1.6 0.2
1139G>C
Sequence Walker  
c71369408g 71369399 185 71369584 -1.6 0.0 1.6 1.0 101.1 -2.3 -1.9 0.4
1190C>T
Sequence Walker  
g71369357a 71369318 266 71369584 -7.6 0.6 8.2 1.5 147.5 -3.6 -1.8 1.8
1327C>T
Sequence Walker  
g71369220a 71369209 375 71369584 0.1 0.6 0.5 1.5 146.3 -1.9 -1.8 0.1
1337G>A
Sequence Walker  
c71369210t 71369209 375 71369584 0.1 8.2 8.2 286.2 28616.6 -1.9 -0.1 1.8
1342G>C
Sequence Walker  
c71369205g 71369203 381 71369584 -4.7 1.2 6.0 2.3 234.6 -3.0 -1.7 1.3
1406G>C
Sequence Walker  
c71369141g 71369118 466 71369584 2.2 3.1 0.8 1.8 178.1 -1.5 -1.3 0.2