Gene: DHCR7
mRNA Accession: AF034544
Mutation:DHCR7.txt
Chromosome: chr 11

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
111G>A
Sequence Walker  
c71377947t 71377960 0 71377960 8.8 8.8 0.0 1.0 100 -0.0 -0.0 0.0
111G>A
Sequence Walker  
c71377947t 71377956 4 71377960 0.0 0.0 0.0 1.0 100 -1.9 -1.9 0.0
111G>A
Sequence Walker  
c71377947t 71377900 60 71377960 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
111G>A
Sequence Walker  
c71377947t 71377898 62 71377960 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
452G>A
Sequence Walker  
c71375145t 71375116 69 71375185 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
452G>A
Sequence Walker  
c71375145t 71375097 88 71375185 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
IVS8-1G>C
Sequence Walker  
c71369584g 71369592 -8 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
IVS8-1G>C
Sequence Walker  
c71369584g 71369554 30 71369584 4.3 4.3 0.0 1.0 100 -1.0 -1.0 0.0
IVS8-1G>C
Sequence Walker  
c71369584g 71369539 45 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
151C>T
Sequence Walker  
g71377907a 71377869 91 71377960 1.9 1.9 0.0 1.0 100 -1.5 -1.5 0.0
151C>T
Sequence Walker  
g71377907a 71377864 96 71377960 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0
278C>T
Sequence Walker  
g71377780a 71377737 -1 71377736 9.6 9.6 0.0 1.0 100 0.2 0.2 0.0
278C>T
Sequence Walker  
g71377780a 71377732 4 71377736 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
278C>T
Sequence Walker  
g71377780a 71377729 7 71377736 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
296T>C
Sequence Walker  
a71377762g 71377732 4 71377736 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
296T>C
Sequence Walker  
a71377762g 71377729 7 71377736 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
326T>C
Sequence Walker  
a71376093g 71376098 0 71376098 6.7 6.7 0.0 1.0 100 -0.5 -0.5 0.0
326T>C
Sequence Walker  
a71376093g 71376066 32 71376098 0.2 0.2 0.0 1.0 100 -1.9 -1.9 0.0
326T>C
Sequence Walker  
a71376093g 71376060 38 71376098 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
326T>C
Sequence Walker  
a71376093g 71376059 39 71376098 3.3 3.3 0.0 1.0 100 -1.2 -1.2 0.0
356A>T
Sequence Walker  
t71376063a 71376084 14 71376098 0.0 0.0 0.0 1.0 100 -1.9 -1.9 0.0
356A>T
Sequence Walker  
t71376063a 71376066 32 71376098 0.2 0.2 0.0 1.0 100 -1.9 -1.9 0.0
440G>A
Sequence Walker  
c71375157t 71375185 0 71375185 11.8 11.8 0.0 1.0 100 0.6 0.6 0.0
440G>A
Sequence Walker  
c71375157t 71375116 69 71375185 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
443T>G
Sequence Walker  
a71375154c 71375116 69 71375185 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
461C>T
Sequence Walker  
g71375136a 71375097 88 71375185 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
461C>T
Sequence Walker  
g71375136a 71375085 100 71375185 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
461C>G
Sequence Walker  
g71375136c 71375097 88 71375185 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
461C>G
Sequence Walker  
g71375136c 71375085 100 71375185 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
470T>C
Sequence Walker  
a71375127g 71375097 88 71375185 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
470T>C
Sequence Walker  
a71375127g 71375085 100 71375185 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
502T>A
Sequence Walker  
a71375095t 71375116 69 71375185 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
506C>T
Sequence Walker  
g71375091a 71375116 69 71375185 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
506C>T
Sequence Walker  
g71375091a 71375097 88 71375185 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
523G>C
Sequence Walker  
c71375074g 71375097 -127 71374970 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
523G>C
Sequence Walker  
c71375074g 71375085 -115 71374970 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
529T>C
Sequence Walker  
a71375068g 71375097 -127 71374970 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
529T>C
Sequence Walker  
a71375068g 71375085 -115 71374970 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
533T>A
Sequence Walker  
a71375064t 71375085 -115 71374970 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
536C>T
Sequence Walker  
g71375061a 71375085 -115 71374970 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
546G>C
Sequence Walker  
c71375051g 71375003 -33 71374970 2.6 2.6 0.0 1.0 100 -1.4 -1.4 0.0
724C>T
Sequence Walker  
g71372730a 71372685 143 71372828 8.1 8.1 0.0 1.0 100 -0.2 -0.2 0.0
724C>T
Sequence Walker  
g71372730a 71372680 148 71372828 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
725G>A
Sequence Walker  
c71372729t 71372685 143 71372828 8.1 8.1 0.0 1.0 100 -0.2 -0.2 0.0
725G>A
Sequence Walker  
c71372729t 71372680 148 71372828 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
725G>A
Sequence Walker  
c71372729t 71372677 151 71372828 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
728C>G
Sequence Walker  
g71372726c 71372685 143 71372828 8.1 8.1 0.0 1.0 100 -0.2 -0.2 0.0
728C>G
Sequence Walker  
g71372726c 71372680 148 71372828 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
728C>G
Sequence Walker  
g71372726c 71372677 151 71372828 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
730G>A
Sequence Walker  
c71372724t 71372685 -63 71372622 8.1 8.1 0.0 1.0 100 -0.2 -0.2 0.0
730G>A
Sequence Walker  
c71372724t 71372680 -58 71372622 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
730G>A
Sequence Walker  
c71372724t 71372677 -55 71372622 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
740C>T
Sequence Walker  
g71372714a 71372685 -63 71372622 8.1 8.1 0.0 1.0 100 -0.2 -0.2 0.0
740C>T
Sequence Walker  
g71372714a 71372680 -58 71372622 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
740C>T
Sequence Walker  
g71372714a 71372677 -55 71372622 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
744G>T
Sequence Walker  
c71372710a 71372680 -58 71372622 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
744G>T
Sequence Walker  
c71372710a 71372677 -55 71372622 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
841G>A
Sequence Walker  
c71371678t 71371688 0 71371688 9.3 9.3 0.0 1.0 100 0.1 0.1 0.0
852C>A
Sequence Walker  
g71371667t 71371688 0 71371688 9.3 9.3 0.0 1.0 100 0.1 0.1 0.0
906C>G
Sequence Walker  
g71371613c 71371563 -8 71371555 3.3 3.3 0.0 1.0 100 -1.2 -1.2 0.0
920G>A
Sequence Walker  
c71371599t 71371563 -8 71371555 3.3 3.3 0.0 1.0 100 -1.2 -1.2 0.0
920G>A
Sequence Walker  
c71371599t 71371556 -1 71371555 8.0 8.0 0.0 1.0 100 -0.2 -0.2 0.0
925G>A
Sequence Walker  
c71371594t 71371563 -8 71371555 3.3 3.3 0.0 1.0 100 -1.2 -1.2 0.0
925G>A
Sequence Walker  
c71371594t 71371556 -1 71371555 8.0 8.0 0.0 1.0 100 -0.2 -0.2 0.0
931T>G
Sequence Walker  
a71371588c 71371556 -1 71371555 8.0 8.0 0.0 1.0 100 -0.2 -0.2 0.0
932G>A
Sequence Walker  
c71371587t 71371556 -1 71371555 8.0 8.0 0.0 1.0 100 -0.2 -0.2 0.0
970T>C
Sequence Walker  
a71369577g 71369592 -8 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
970T>C
Sequence Walker  
a71369577g 71369584 0 71369584 13.5 13.5 0.0 1.0 100 1.0 1.0 0.0
970T>C
Sequence Walker  
a71369577g 71369583 1 71369584 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
970T>C
Sequence Walker  
a71369577g 71369539 45 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
976G>T
Sequence Walker  
c71369571a 71369592 -8 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
976G>T
Sequence Walker  
c71369571a 71369584 0 71369584 13.5 13.5 0.0 1.0 100 1.0 1.0 0.0
976G>T
Sequence Walker  
c71369571a 71369583 1 71369584 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
976G>T
Sequence Walker  
c71369571a 71369539 45 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
986C>T
Sequence Walker  
g71369561a 71369584 0 71369584 13.5 13.5 0.0 1.0 100 1.0 1.0 0.0
986C>T
Sequence Walker  
g71369561a 71369583 1 71369584 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
1022T>C
Sequence Walker  
a71369525g 71369554 30 71369584 4.3 4.3 0.0 1.0 100 -1.0 -1.0 0.0
1022T>C
Sequence Walker  
a71369525g 71369539 45 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1022T>C
Sequence Walker  
a71369525g 71369476 108 71369584 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
1084C>T
Sequence Walker  
g71369463a 71369476 108 71369584 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
1084C>T
Sequence Walker  
g71369463a 71369429 155 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1138T>C
Sequence Walker  
a71369409g 71369429 155 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1138T>C
Sequence Walker  
a71369409g 71369383 201 71369584 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
1139G>A
Sequence Walker  
c71369408t 71369429 155 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1139G>C
Sequence Walker  
c71369408g 71369429 155 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1190C>T
Sequence Walker  
g71369357a 71369383 201 71369584 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
1327C>T
Sequence Walker  
g71369220a 71369240 344 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1328G>A
Sequence Walker  
c71369219t 71369240 344 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1331G>A
Sequence Walker  
c71369216t 71369240 344 71369584 0.8 0.8 0.0 1.0 100 -1.8 -1.8 0.0
1331G>A
Sequence Walker  
c71369216t 71369209 375 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
1342G>C
Sequence Walker  
c71369205g 71369209 375 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
1342G>A
Sequence Walker  
c71369205t 71369209 375 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
1349G>T
Sequence Walker  
c71369198a 71369209 375 71369584 0.1 0.1 0.0 1.0 100 -1.9 -1.9 0.0
1384T>C
Sequence Walker  
a71369163g 71369118 466 71369584 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0
1400C>T
Sequence Walker  
g71369147a 71369118 466 71369584 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0