Gene: DHCR7
mRNA Accession: AF034544
Mutation:DHCR7.txt
Chromosome: chr 11

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
762insT
Sequence Walker
i71372691,71372692a 71372677 -55 71372622 0.8 0.7 -0.1 -1.1 91.7 -1.8 -1.8 -0.0
IVS8-1G>C
Sequence Walker
c71369584g 71369584 0 71369584 13.5 6.2 -7.3 -156.4 0.6 1.0 -0.6 -1.6
321G>C
Sequence Walker
c71377737g 71377737 -1 71377736 9.6 2.3 -7.3 -156.4 0.6 0.2 -1.4 -1.6
326T>C
Sequence Walker  
a71376093g 71376084 14 71376098 0.0 -0.6 -0.6 -1.0 NA -1.9 -2.1 -0.1
461C>G
Sequence Walker
g71375136c 71375116 69 71375185 1.8 0.8 -1.0 -2.0 49.2 -1.5 -1.8 -0.2
470T>C
Sequence Walker
a71375127g 71375116 69 71375185 1.8 1.3 -0.5 -1.5 68.3 -1.5 -1.7 -0.1
502T>A
Sequence Walker
a71375095t 71375097 88 71375185 1.6 1.1 -0.5 -1.4 72.2 -1.6 -1.7 -0.1
502T>A
Sequence Walker  
a71375095t 71375085 100 71375185 0.7 -2.2 -2.8 -1.6 NA -1.8 -2.4 -0.6
808A>G
Sequence Walker
t71372646c 71372623 -1 71372622 6.6 6.2 -0.3 -1.2 80.5 -0.5 -0.6 -0.1
931T>G
Sequence Walker
a71371588c 71371563 -8 71371555 3.3 2.4 -0.9 -1.9 53.8 -1.2 -1.4 -0.2
952T>A
Sequence Walker
a71371567t 71371563 -8 71371555 3.3 0.5 -2.8 -7.2 13.8 -1.2 -1.8 -0.6
952T>A
Sequence Walker
a71371567t 71371556 -1 71371555 8.0 5.4 -2.6 -6.0 16.5 -0.2 -0.8 -0.6
957G>A
Sequence Walker
c71371562t 71371563 -8 71371555 3.3 2.3 -1.0 -1.9 51.5 -1.2 -1.4 -0.2
970T>C
Sequence Walker
a71369577g 71369554 30 71369584 4.3 4.2 -0.1 -1.1 92.4 -1.0 -1.0 -0.0
986C>T
Sequence Walker
g71369561a 71369539 45 71369584 0.8 0.8 -0.1 -1.0 96.5 -1.8 -1.8 -0.0
1055G>A
Sequence Walker
c71369492t 71369476 108 71369584 1.6 1.6 -0.0 -1.0 96.9 -1.6 -1.6 -0.0
1058T>C
Sequence Walker
a71369489g 71369476 108 71369584 1.6 1.2 -0.4 -1.3 74.0 -1.6 -1.7 -0.1
1328G>A
Sequence Walker  
c71369219t 71369209 375 71369584 0.1 -0.4 -0.4 -1.1 NA -1.9 -2.0 -0.1