Gene: CYP3A4
mRNA Accession: M18907
Mutation:CYP3A4.txt
Chromosome: chr 7

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1088C>T
Sequence Walker  
g98957424a 98957437 49 98957486 2.3 2.3 0.0 1.0 100 -1.7 -1.7 0.0
1088C>T
Sequence Walker  
g98957424a 98957434 52 98957486 5.9 5.9 0.0 1.0 100 -0.6 -0.6 0.0
1088C>T
Sequence Walker  
g98957424a 98957386 100 98957486 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
1117C>T
Sequence Walker  
g98957395a 98957437 49 98957486 2.3 2.3 0.0 1.0 100 -1.7 -1.7 0.0
1117C>T
Sequence Walker  
g98957395a 98957434 52 98957486 5.9 5.9 0.0 1.0 100 -0.6 -0.6 0.0
1117C>T
Sequence Walker  
g98957395a 98957386 100 98957486 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
1117C>T
Sequence Walker  
g98957395a 98957370 116 98957486 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
1247C>T
Sequence Walker  
g98957265a 98957304 -46 98957258 0.5 0.5 0.0 1.0 100 -2.3 -2.3 0.0
1247C>T
Sequence Walker  
g98957265a 98957294 -36 98957258 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
1247C>T
Sequence Walker  
g98957265a 98957258 0 98957258 4.8 4.8 0.0 1.0 100 -1.0 -1.0 0.0
1247C>T
Sequence Walker  
g98957265a 98957244 14 98957258 1.6 1.6 0.0 1.0 100 -2.0 -2.0 0.0
1334T>C
Sequence Walker  
a98956119g 98956143 57 98956200 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
1334T>C
Sequence Walker  
a98956119g 98956115 85 98956200 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
167G>A
Sequence Walker  
c98973297t 98973348 -49 98973299 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
167G>A
Sequence Walker  
c98973297t 98973344 -45 98973299 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
167G>A
Sequence Walker  
c98973297t 98973291 8 98973299 2.1 2.1 0.0 1.0 100 -1.8 -1.8 0.0
167G>A
Sequence Walker  
c98973297t 98973263 36 98973299 5.2 5.2 0.0 1.0 100 -0.9 -0.9 0.0
167G>A
Sequence Walker  
c98973297t 98973253 46 98973299 5.2 5.2 0.0 1.0 100 -0.9 -0.9 0.0
167G>A
Sequence Walker  
c98973297t 98973251 48 98973299 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
352A>G
Sequence Walker  
t98965420c 98965441 13 98965454 2.6 2.6 0.0 1.0 100 -1.7 -1.7 0.0
389G>A
Sequence Walker  
c98965383t 98965339 0 98965339 6.9 6.9 0.0 1.0 100 -0.3 -0.3 0.0
44T>C
Sequence Walker  
a98979256g 98979305 -77 98979228 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
44T>C
Sequence Walker  
a98979256g 98979302 -74 98979228 1.3 1.3 0.0 1.0 100 -2.1 -2.1 0.0
44T>C
Sequence Walker  
a98979256g 98979242 -14 98979228 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
44T>C
Sequence Walker  
a98979256g 98979228 0 98979228 5.4 5.4 0.0 1.0 100 -0.8 -0.8 0.0
44T>C
Sequence Walker  
a98979256g 98979224 4 98979228 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
485G>A
Sequence Walker  
c98965022t 98965054 -69 98964985 3.3 3.3 0.0 1.0 100 -1.4 -1.4 0.0
485G>A
Sequence Walker  
c98965022t 98965044 -59 98964985 0.0 0.0 0.0 1.0 100 -2.4 -2.4 0.0
485G>A
Sequence Walker  
c98965022t 98965038 -53 98964985 7.0 7.0 0.0 1.0 100 -0.3 -0.3 0.0
485G>A
Sequence Walker  
c98965022t 98965007 -22 98964985 3.6 3.6 0.0 1.0 100 -1.3 -1.3 0.0
485G>A
Sequence Walker  
c98965022t 98964985 0 98964985 7.2 7.2 0.0 1.0 100 -0.2 -0.2 0.0
485G>A
Sequence Walker  
c98965022t 98964981 4 98964985 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
508G>A
Sequence Walker  
c98964999t 98965044 -59 98964985 0.0 0.0 0.0 1.0 100 -2.4 -2.4 0.0
508G>A
Sequence Walker  
c98964999t 98965038 -53 98964985 7.0 7.0 0.0 1.0 100 -0.3 -0.3 0.0
508G>A
Sequence Walker  
c98964999t 98965007 -22 98964985 3.6 3.6 0.0 1.0 100 -1.3 -1.3 0.0
508G>A
Sequence Walker  
c98964999t 98964985 0 98964985 7.2 7.2 0.0 1.0 100 -0.2 -0.2 0.0
508G>A
Sequence Walker  
c98964999t 98964981 4 98964985 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
520G>C
Sequence Walker  
c98964987g 98965038 -53 98964985 7.0 7.0 0.0 1.0 100 -0.3 -0.3 0.0
520G>C
Sequence Walker  
c98964987g 98965007 -22 98964985 3.6 3.6 0.0 1.0 100 -1.3 -1.3 0.0
520G>C
Sequence Walker  
c98964987g 98964981 4 98964985 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
653C>G
Sequence Walker  
g98963589c 98963571 0 98963571 5.4 5.4 0.0 1.0 100 -0.8 -0.8 0.0
831insA
Sequence Walker  
i98961628,98961629t 98961655 7 98961662 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
831insA
Sequence Walker  
i98961628,98961629t 98961594 68 98961662 7.2 7.2 0.0 1.0 100 -0.2 -0.2 0.0