Gene: CYP3A4
mRNA Accession: M18907
Mutation:CYP3A4.txt
Chromosome: chr 7

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
167G>A
Sequence Walker
c98973297t 98973298 1 98973299 2.5 1.5 -1.0 -1.9 51.5 -1.4 -1.6 -0.2
44T>C
Sequence Walker
a98979256g 98979247 -19 98979228 4.3 3.7 -0.6 -1.5 66.7 -1.0 -1.1 -0.1
653C>G
Sequence Walker
g98963589c 98963575 -4 98963571 3.2 1.9 -1.3 -2.5 40.5 -1.2 -1.5 -0.3
653C>G
Sequence Walker
g98963589c 98963572 -1 98963571 3.2 1.9 -1.3 -2.5 40.3 -1.2 -1.5 -0.3
653C>G
Sequence Walker
g98963589c 98963571 0 98963571 3.2 2.4 -0.8 -1.8 55.6 -1.2 -1.4 -0.2
653C>G
Sequence Walker  
g98963589c 98963574 -3 98963571 0.6 -0.5 -1.1 -1.5 NA -1.8 -2.0 -0.2
831insA
Sequence Walker
i98961628,98961629t 98961623 39 98961662 5.1 3.5 -1.6 -3.0 33.4 -0.8 -1.2 -0.3