Accession number = M33388 Chrosomome number = chrm_22

1978C>T.

1869T>C.

1661G>C; 2850C>T; 4180G>C.

1039C>T; 1661G>C; 2850C>T; 4180G>C.

1661G>C; 2470T>C; 2850C>T; 4180G>C.

2850C>T; 4180G>C.

997C>G; 1661G>C; 2850C>T; 4180G>C.

1661G>C; 1724C>T; 2850C>T; 4180G>C.

1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>C.

1661G>C; 2480C>T; 2850C>T; 4180G>C.

1661G>C; 2850C>T; 2939G>A; 4180G>C.

1661G>C; 2850C>T; 4115C>T; 4180G>C.

1661G>C; 2850C>T; 4180G>C.

100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>C.

100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>C.

100C>T; 1661G>C; 1846G>A; 4180G>C.

100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>C.

2935A>C.

1661G>C; 1758G>T 2850C>T; 4180G>C.

2613-2615delAGA.

100C>T; 1661G>C; 4180G>C.

100C>T; 1039C>T; 1661G>C; 4180G>C.

883G>C; 1661G>C; 2850C>T; 4180G>C.

124G>A; 1661G>C; 2850C>T; 4180G>C.

100C>T; 1758G>A 2850C>T; 4180G>C.

1661G>C; 1758G>A; 2850C>T; 4180G>C.

1661G>C; 2539-2542delAACT; 2850C>T; 4180G>C.

1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>C.

82C>T.

957C>T.

2853A>C.

3198C>G.

3277T>C.

19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>C.

1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>C.

1661G>C; 2850C>T; 4180G>C.

1661G>C; 2850C>T; 4042G>A; 4180G>C.

1661G>C; 2850C>T; 3853G>A; 4180G>C.

2850C>T.

31G>A; 1661G>C; 2850C>T; 4180G>C.

31G>A; 1661G>C; 2850C>T; 4180G>C.

100C>T; 1039C>T; 1661G>C; 4180G>C;.

100C>T; 1039C>T; 1661G>C; 1943G>A; 4180G>C;.

2587-2590delGACT.

1661G>C; 4180G>C.

1023C>T; 1661G>C; 4180G>C.

1661G>C; 2850C>T; 4180G>C.

77G>A.




1978C>T

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3627 (NA)donor:
acceptor:
1978C>Tc3597t 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0



1869T>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3504 (NA)donor:
acceptor:
1869T>Ct3488c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1869T>Ct3488c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0



1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1039C>T; 1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange2675 (2675)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1039C>T; 1661G>C; 2850C>T; 4180G>Cc2658t.g3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2470T>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2470T>C; 2850C>T; 4180G>Cg3280c.t4089c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange4478 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
2850C>T; 4180G>Cc4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



997C>G; 1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange2596 (2596)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)997C>G; 1661G>C; 2850C>T; 4180G>Cc2616g.g3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 1724C>T; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; 1724C>T; 2850C>T; 4180G>Cg3280c.c3343t.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; 2470T>C; 2575C>A; 2850C>T; 4180G>Cg3280c.t4089c.c4194a.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2480C>T; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; 2480C>T; 2850C>T; 4180G>Cg3280c.c4099t.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2850C>T; 2939G>A; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 2939G>A; 4180G>Cg3280c.c4469t.g4558a.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2850C>T; 4115C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4115C>T; 4180G>Cg3280c.c4469t.c5734t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 3887T>C; 4180G>Cc1719t.g3280c.g3465a.t5506c.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.c2658t.g3280c.g3465a.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1661G>C; 1846G>A; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
100C>T; 1661G>C; 1846G>A; 4180G>Cc1719t.g3280c.g3465a.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (1800)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (1831)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (1867)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (1871)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (1918)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (1991)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (2010)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (2096)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (2198)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (2281)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (2306)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (2342)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (2408)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (2461)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (2554)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)100C>T; 1661G>C; 1846G>A; 2850C>T; 4180G>Cc1719t.g3280c.g3465a.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



2935A>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange4569 (NA)donor:
acceptor:
2935A>Ca4554c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0



1661G>C; 1758G>T 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
decreased3378 (3378)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 8.1 4.8 3.3 0.1 0.0 -1.0 1.0
nochange3382 (3382)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; 1758G>T 2850C>T; 4180G>Cg3280c.g3377t.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



2613-2615delAGA

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
decreased4237 (NA)donor:
acceptor:
2613-2615delAGAd4234,4236 11.0 10.0 1.0 0.5 0.9 0.6 0.3
nochange4255 (NA)donor:
acceptor:
2613-2615delAGAd4234,4236 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
2613-2615delAGAd4234,4236 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0



100C>T; 1661G>C; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
100C>T; 1661G>C; 4180G>Cc1719t.g3280c.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1039C>T; 1661G>C; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>Cc1719t.c2658t.g3280c.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



883G>C; 1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange2554 (2554)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)883G>C; 1661G>C; 2850C>T; 4180G>Cg2502c.g3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



124G>A; 1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (1800)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (1831)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (1867)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (1871)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (1918)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (1991)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (2010)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (2096)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (2198)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (2281)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (2306)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (2342)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (2408)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (2461)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (2554)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)124G>A; 1661G>C; 2850C>T; 4180G>Cg1743a.g3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1758G>A 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (1800)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (1831)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (1867)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (1871)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (1918)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (1991)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (2010)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (2096)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (2198)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (2281)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (2306)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (2342)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (2408)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (2461)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (2554)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
decreased3378 (3378)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 8.1 5.1 3.1 0.1 0.0 -0.9 0.9
nochange3382 (3382)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)100C>T; 1758G>A 2850C>T; 4180G>Cc1719t.g3377a.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 1758G>A; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
decreased3378 (3378)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 8.1 5.1 3.1 0.1 0.0 -0.9 0.9
nochange3382 (3382)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; 1758G>A; 2850C>T; 4180G>Cg3280c.g3377a.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2539-2542delAACT; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; 2539-2542delAACT; 2850C>T; 4180G>Cg3280c.d4161,4164.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (3325)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)1661G>C; ;1978C>T; 1979T>C; 2850C>T; 4180G>Cg3280c.c3597t.t3598c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



82C>T

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1677 (NA)donor:
acceptor:
82C>Tc1701t 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0



957C>T

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange2554 (NA)donor:
acceptor:
957C>Tc2576t 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (NA)donor:
acceptor:
957C>Tc2576t 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
increased2575 (NA)donor:
acceptor:
957C>Tc2576t<= 0.0 2.7>= 2.7 0.2 0.0 -1.6 -1.6



2853A>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange4478 (NA)donor:
acceptor:
2853A>Ca4472c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
2853A>Ca4472c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0



3198C>G

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
increased4814 (NA)donor:
acceptor:
3198C>Gc4817g 7.8 8.3 0.5 0.7 -0.1 0.1 0.2
nochange4833 (NA)donor:
acceptor:
3198C>Gc4817g 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0



3277T>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange4877 (NA)donor:
acceptor:
3277T>Ct4896c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
3277T>Ct4896c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0



19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1609 (1609)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange1618 (1618)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 8.8 8.8 0.0 1.0 0.2 0.2 0.0
nochange1677 (1677)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange1800 (1800)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (1831)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (1867)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (1871)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (1918)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (1991)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (2010)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (2096)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (2198)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (2281)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (2306)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (2342)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (2408)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (2461)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (2554)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
decreased3325 (3325)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.9 3.7 0.3 0.8 -1.2 -1.3 0.1
nochange3329 (3329)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)19G>A; 1661G>C; 1704C>G; 2850C>T; 4180G>Cg1638a.g3280c.c3323g.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1659G>A; 1661G>C; 2850C>T; 3183G>A; 4180G>Cg3278a.g3280c.c4469t.g4802a.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4180G>Cg3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2850C>T; 4042G>A; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 4042G>A; 4180G>Cg3280c.c4469t.g5661a.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



1661G>C; 2850C>T; 3853G>A; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange3325 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (NA)donor:
acceptor:
1661G>C; 2850C>T; 3853G>A; 4180G>Cg3280c.c4469t.g5472a.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



2850C>T

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange4478 (NA)donor:
acceptor:
2850C>Tc4469t 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0



31G>A; 1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1618 (1618)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.8 8.8 0.0 1.0 0.2 0.2 0.0
nochange1677 (1677)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange1800 (1800)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (1831)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (1867)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (1871)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (1918)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (1991)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (2010)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (2096)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (2198)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (2281)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (2306)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (2342)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (2408)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (2461)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (2554)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



31G>A; 1661G>C; 2850C>T; 4180G>C

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1618 (1618)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.8 8.8 0.0 1.0 0.2 0.2 0.0
nochange1677 (1677)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange1800 (1800)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (1831)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (1867)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (1871)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (1918)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (1991)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (2010)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (2096)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (2198)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (2281)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (2306)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (2342)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (2408)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (2461)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2554 (2554)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange2596 (2596)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.6 4.6 0.0 1.0 -1.0 -1.0 0.0
nochange2675 (2675)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2685 (2685)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.4 5.4 0.0 1.0 -0.8 -0.8 0.0
nochange2718 (2718)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange2722 (2722)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2787 (2787)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2826 (2826)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange2828 (2828)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange2862 (2862)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange2903 (2903)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.4 7.4 0.0 1.0 -0.2 -0.2 0.0
nochange2943 (2943)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange2969 (2969)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange2980 (2980)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange3025 (3025)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3031 (3031)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.9 5.9 0.0 1.0 -0.6 -0.6 0.0
nochange3046 (3046)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3080 (3080)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.5 6.5 0.0 1.0 -0.5 -0.5 0.0
nochange3095 (3095)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange3161 (3161)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3168 (3168)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange3175 (3175)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.1 6.1 0.0 1.0 -0.6 -0.6 0.0
nochange3325 (3325)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.9 3.9 0.0 1.0 -1.2 -1.2 0.0
nochange3329 (3329)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange3378 (3378)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange3382 (3382)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3504 (3504)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange3513 (3513)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3548 (3548)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange3627 (3627)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3675 (3675)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange3756 (3756)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.6 5.6 0.0 1.0 -0.7 -0.7 0.0
nochange3808 (3808)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.4 6.4 0.0 1.0 -0.5 -0.5 0.0
nochange3818 (3818)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.8 4.8 0.0 1.0 -1.0 -1.0 0.0
nochange3833 (3833)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange3865 (3865)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.7 2.7 0.0 1.0 -1.6 -1.6 0.0
nochange3903 (3903)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange3911 (3911)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange3940 (3940)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.9 6.9 0.0 1.0 -0.3 -0.3 0.0
nochange3945 (3945)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.2 7.2 0.0 1.0 -0.3 -0.3 0.0
nochange3952 (3952)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.2 8.2 0.0 1.0 0.1 0.1 0.0
nochange4011 (4011)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4054 (4054)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.8 2.8 0.0 1.0 -1.6 -1.6 0.0
nochange4056 (4056)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.8 3.8 0.0 1.0 -1.3 -1.3 0.0
nochange4060 (4060)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4237 (4237)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 11.0 11.0 0.0 1.0 0.9 0.9 0.0
nochange4255 (4255)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.8 6.8 0.0 1.0 -0.4 -0.4 0.0
nochange4268 (4268)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.7 -1.7 0.0
nochange4271 (4271)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.0 6.0 0.0 1.0 -0.6 -0.6 0.0
nochange4316 (4316)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange4360 (4360)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.5 4.5 0.0 1.0 -1.1 -1.1 0.0
nochange4478 (4478)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4505 (4505)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.7 4.7 0.0 1.0 -1.0 -1.0 0.0
nochange4569 (4569)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.2 4.2 0.0 1.0 -1.2 -1.2 0.0
nochange4612 (4612)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.6 -1.6 0.0
nochange4681 (4681)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.8 5.8 0.0 1.0 -0.7 -0.7 0.0
nochange4709 (4709)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange4754 (4754)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.9 2.9 0.0 1.0 -1.5 -1.5 0.0
nochange4814 (4814)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 7.8 7.8 0.0 1.0 -0.1 -0.1 0.0
nochange4833 (4833)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange4877 (4877)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange4908 (4908)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.5 3.5 0.0 1.0 -1.4 -1.4 0.0
nochange4964 (4964)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.4 8.4 0.0 1.0 0.1 0.1 0.0
nochange5008 (5008)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5036 (5036)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.1 8.1 0.0 1.0 0.0 0.0 0.0
nochange5103 (5103)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.1 5.1 0.0 1.0 -0.9 -0.9 0.0
nochange5158 (5158)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5225 (5225)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange5242 (5242)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 6.3 6.3 0.0 1.0 -0.5 -0.5 0.0
nochange5334 (5334)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.4 3.4 0.0 1.0 -1.4 -1.4 0.0
nochange5336 (5336)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange5347 (5347)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.6 2.6 0.0 1.0 -1.6 -1.6 0.0
nochange5560 (5560)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 5.7 5.7 0.0 1.0 -0.7 -0.7 0.0
nochange5566 (5566)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange5778 (5778)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
decreased5795 (5795)31G>A; 1661G>C; 2850C>T; 4180G>Cg1650a.g3280c.c4469t.g5799c 8.6 4.6 3.9 0.1 0.2 -1.0 1.2



100C>T; 1039C>T; 1661G>C; 4180G>C;

Sequence Walker

Type of changeBase[Ri changed] (relative position)Natural SiteHUGO representationActual mutationInitial(Ri)Final(Ri)Delta Rimin fold reductionInitial(Z)Final(z)Delta Z
nochange1800 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 11.5 11.5 0.0 1.0 1.1 1.1 0.0
nochange1831 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 3.0 3.0 0.0 1.0 -1.5 -1.5 0.0
nochange1867 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 7.9 7.9 0.0 1.0 -0.0 -0.0 0.0
nochange1871 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange1918 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 4.3 4.3 0.0 1.0 -1.1 -1.1 0.0
nochange1991 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 3.2 3.2 0.0 1.0 -1.5 -1.5 0.0
nochange2010 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 3.7 3.7 0.0 1.0 -1.3 -1.3 0.0
nochange2096 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 3.3 3.3 0.0 1.0 -1.4 -1.4 0.0
nochange2198 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 4.1 4.1 0.0 1.0 -1.2 -1.2 0.0
nochange2281 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 4.4 4.4 0.0 1.0 -1.1 -1.1 0.0
nochange2306 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 3.1 3.1 0.0 1.0 -1.5 -1.5 0.0
nochange2342 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 7.3 7.3 0.0 1.0 -0.2 -0.2 0.0
nochange2408 (NA)donor:
acceptor:
100C>T; 1039C>T; 1661G>C; 4180G>C;c1719t.c2658t.g3280c.g5799c 2.5 2.5 0.0 1.0 -1.7 -1.7 0.0
nochange2461 (NA)