Gene: COL1A2
mRNA Accession: J03464
Mutation:COL1A2.txt
Chromosome: chr 7

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS33+5G>A
Sequence Walker
g93646096a 93646090 -2 93646092 1.9 1.5 -0.4 -1.3 75.8 -1.9 -2.0 -0.1
IVS33+5G>A
Sequence Walker
g93646096a 93646092 0 93646092 6.7 3.2 -3.5 -11.5 8.7 -0.4 -1.5 -1.1
IVS40+5G>A
Sequence Walker
g93650662a 93650658 0 93650658 6.6 3.1 -3.5 -11.5 8.7 -0.4 -1.5 -1.1
IVS40+5G>A
Sequence Walker  
g93650662a 93650662 4 93650658 3.2 -9.6 -12.8 -9.4 NA -1.5 -5.3 -3.9
IVS46+2T>C
Sequence Walker  
t93654071c 93654070 0 93654070 6.2 -1.2 -7.5 -75.2 NA -0.5 -2.8 -2.3
IVS12+2T>G
Sequence Walker
t93633844g 93633843 0 93633843 9.1 0.8 -8.2 -295.8 0.3 0.3 -2.2 -2.5
IVS12-3T>A
Sequence Walker  
t93635383a 93635382 -3 93635385 5.1 -2.7 -7.8 -34.3 NA -0.9 -3.3 -2.4
IVS13+4-+22delAGTATTGACTACTTCATTG
Sequence Walker  
d93635434,93635452 93635431 0 93635431 7.5 -0.7 -8.2 -180.6 NA -0.2 -2.6 -2.5
IVS13+4-+22delAGTATTGACTACTTCATTG
Sequence Walker  
d93635434,93635452 93635452 21 93635431 3.1 -14.1 -17.2 -8.5 NA -1.5 -6.7 -5.2
IVS16+1G>A
Sequence Walker  
g93636363a 93636363 0 93636363 7.5 -5.3 -12.8 -177.2 NA -0.2 -4.1 -3.9
IVS16+1G>T
Sequence Walker  
g93636363t 93636363 0 93636363 7.5 -0.3 -7.8 -177.2 NA -0.2 -2.5 -2.4
IVS16+2T>C
Sequence Walker  
t93636364c 93636363 0 93636363 7.5 -0.0 -7.5 -177.2 NA -0.2 -2.4 -2.3
IVS21+2-+40del
Sequence Walker  
d93638068,93638106 93638067 0 93638067 4.1 -6.9 -11.0 -17.6 NA -1.2 -4.5 -3.3
IVS21+5G>A
Sequence Walker
g93638071a 93638067 0 93638067 4.1 0.6 -3.5 -11.5 8.7 -1.2 -2.2 -1.1
IVS26+3A>G
Sequence Walker
a93640678g 93640676 0 93640676 8.3 7.9 -0.4 -1.3 75.7 0.1 -0.0 -0.1
IVS26+3A>G
Sequence Walker  
a93640678g 93640680 4 93640676 2.2 -0.1 -2.3 -4.5 NA -1.8 -2.5 -0.7
IVS27-2A>G
Sequence Walker
a93641431g 93641434 2 93641432 1.5 0.5 -1.0 -2.0 49.9 -2.0 -2.3 -0.3
IVS32+1G>A
Sequence Walker  
g93645371a 93645371 0 93645371 9.9 -2.9 -12.8 -960.7 NA 0.6 -3.3 -3.9
IVS6+1G>A
Sequence Walker  
g93629160a 93629160 0 93629160 5.4 -7.4 -12.8 -42.5 NA -0.8 -4.7 -3.9
IVS6+1G>T
Sequence Walker  
g93629160t 93629160 0 93629160 5.4 -2.4 -7.8 -42.5 NA -0.8 -3.2 -2.4
IVS6+2T>C
Sequence Walker  
t93629161c 93629160 0 93629160 5.4 -2.1 -7.5 -42.5 NA -0.8 -3.1 -2.3
IVS9+3-+13delAAGTATTTACT
Sequence Walker  
d93632434,93632444 93632432 0 93632432 8.3 -5.1 -13.4 -306.3 NA 0.1 -4.0 -4.1
IVS9+3-+13delAAGTATTTACT
Sequence Walker  
d93632434,93632444 93632436 4 93632432 1.1 -18.1 -19.2 -2.1 NA -2.1 -7.9 -5.8
IVS9+5G>A
Sequence Walker
g93632436a 93632432 0 93632432 8.3 4.7 -3.5 -11.5 8.7 0.1 -1.0 -1.1
IVS9+5G>A
Sequence Walker  
g93632436a 93632436 4 93632432 1.1 -11.7 -12.8 -2.1 NA -2.1 -6.0 -3.9
c.1404+1G>A.c.70+717A>G
Sequence Walker  
g93637148a.a93623357g 93637148 0 93637148 5.8 -7.0 -12.8 -57.0 NA -0.7 -4.6 -3.9
c.1404+1G>C.c.540+5G>A
Sequence Walker
g93637148c.g93625302a 93625298 -11850 93637148 11.2 7.7 -3.5 -11.5 8.7 1.0 -0.1 -1.1
c.1404+1G>C.c.540+5G>A
Sequence Walker  
g93637148c.g93625302a 93625302 -11846 93637148 0.5 -12.3 -12.8 -1.4 NA -2.3 -6.2 -3.9
c.1404+1G>C.c.540+5G>A
Sequence Walker  
g93637148c.g93625302a 93637148 0 93637148 5.8 -4.0 -9.8 -57.0 NA -0.7 -3.6 -3.0