Gene: COL1A2
mRNA Accession: J03464
Chromosome: chr 7

Sequence Walker  




IVS5-2A>G


Instruction: a93629104g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93629097 -893629105 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
Increased 93629104 -193629105 1.5 9.1 7.6 191.119111.1 -1.6 0.0 1.7
Decreased93629105 0 93629105 13.9 5.7 -8.2 -286.20.3 1.1 -0.7 -1.8
Increased 93629107 293629105 1.4 1.5 0.1 1.1109.6 -1.6 -1.6 0.0
Decreased93629108 3 93629105 0.9 0.6 -0.3 -1.281.1 -1.7 -1.8 -0.1
Increased 93629115 1093629105 0.5 0.8 0.3 1.3125.6 -1.8 -1.8 0.1
Increased 93629120 1593629105 4.9 5.0 0.0 1.0103.1 -0.9 -0.9 0.0
Sites found for donor
No Change 93629053 -5293629105 3.6 3.6 0.0 1.0100 -1.3 -1.3 0.0
No Change 93629120 1593629105 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0



IVS5-1G>A


Instruction: g93629105a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93629097 -893629105 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
Decreased93629104 -1 93629105 1.5 0.6 -1.0 -1.951.5 -1.6 -1.8 -0.2
Decreased93629105 0 93629105 13.9 6.3 -7.6 -191.10.5 1.1 -0.6 -1.7
Increased 93629107 293629105 1.4 3.1 1.7 3.3334.9 -1.6 -1.3 0.4
Decreased93629108 3 93629105 0.9 0.8 -0.1 -1.191.2 -1.7 -1.8 -0.0
Decreased93629115 10 93629105 0.5 0.1 -0.4 -1.473.8 -1.8 -1.9 -0.1
Decreased93629120 15 93629105 4.9 4.7 -0.2 -1.285.8 -0.9 -0.9 -0.0
increased93629106193629105 -5.9 2.2 8.2 4.7471.7 -3.2 -1.4 1.8
Sites found for donor
No Change 93629120 1593629105 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0



IVS5-1G>C


Instruction: g93629105c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93629097 -893629105 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
Decreased93629105 0 93629105 13.9 6.6 -7.3 -156.40.6 1.1 -0.5 -1.6
Increased 93629107 293629105 1.4 7.4 6.0 62.76265.0 -1.6 -0.3 1.3
Increased 93629108 393629105 0.9 1.1 0.2 1.2115.5 -1.7 -1.7 0.0
Increased 93629115 1093629105 0.5 2.2 1.7 3.2324.1 -1.8 -1.5 0.4
Increased 93629120 1593629105 4.9 6.0 1.1 2.2216.5 -0.9 -0.6 0.2
Decreased93629104-193629105 1.5 -0.4 -1.9 -2.8NA -1.6 -2.0 -0.4
Sites found for donor
No Change 93629120 1593629105 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0



IVS6+1G>A


Instruction: g93629160a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Increased 93629182 2293629160 5.0 5.4 0.4 1.4135.5 -0.8 -0.7 0.1
Sites found for donor
No Change 93629120 -4093629160 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0
Decreased93629160093629160 5.4 -7.4 -12.8 -42.5NA -0.8 -4.7 -3.9



IVS6+1G>T


Instruction: g93629160t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Increased 93629182 2293629160 5.0 5.9 0.9 1.9185.5 -0.8 -0.6 0.2
Sites found for donor
No Change 93629120 -4093629160 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0
Decreased93629160093629160 5.4 -2.4 -7.8 -42.5NA -0.8 -3.2 -2.4



IVS6+2T>C


Instruction: t93629161c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased93629182 22 93629160 5.0 5.0 -0.1 -1.096.1 -0.8 -0.9 -0.0
Sites found for donor
No Change 93629120 -4093629160 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0
Decreased93629160093629160 5.4 -2.1 -7.5 -42.5NA -0.8 -3.1 -2.3



c.279G>A


Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Unprocessed due to the following error. c.279G>A the old base at 93622378 is NOT g! It is t.



IVS9+3-+13delAAGTATTTACT


Instruction: d93632434,93632444 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased936324501893632432 0.2 -9.6 -9.8 -1.2NA -1.9 -4.0 -2.1
Sites found for donor
No Change 93632388 -4493632432 4.3 4.3 0.0 1.0100 -1.1 -1.1 0.0
No Change 93632415 -1793632432 1.7 1.7 0.0 1.0100 -1.9 -1.9 0.0
No Change 93632424 -893632432 5.5 5.5 0.0 1.0100 -0.8 -0.8 0.0
Decreased93632432093632432 8.3 -5.1 -13.4 -306.3NA 0.1 -4.0 -4.1
Decreased93632436493632432 1.1 -18.1 -19.2 -2.1NA -2.1 -7.9 -5.8



IVS9+5G>A


Instruction: g93632436a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased936324501893632432 0.2 -0.1 -0.3 -1.2NA -1.9 -2.0 -0.1
Sites found for donor
No Change 93632388 -4493632432 4.3 4.3 0.0 1.0100 -1.1 -1.1 0.0
No Change 93632415 -1793632432 1.7 1.7 0.0 1.0100 -1.9 -1.9 0.0
No Change 93632424 -893632432 5.5 5.5 0.0 1.0100 -0.8 -0.8 0.0
Decreased93632432 0 93632432 8.3 4.7 -3.5 -11.58.7 0.1 -1.0 -1.1
Decreased93632436493632432 1.1 -11.7 -12.8 -2.1NA -2.1 -6.0 -3.9



IVS12+2T>G


Instruction: t93633844g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased93633842 -1 93633843 0.5 0.0 -0.5 -1.470.0 -1.8 -1.9 -0.1
Sites found for donor
No Change 93633799 -4493633843 1.3 1.3 0.0 1.0100 -2.0 -2.0 0.0
No Change 93633826 -1793633843 1.7 1.7 0.0 1.0100 -1.9 -1.9 0.0
No Change 93633835 -893633843 5.5 5.5 0.0 1.0100 -0.8 -0.8 0.0
No Change 93633837 -693633843 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
Decreased93633843 0 93633843 9.1 0.8 -8.2 -295.80.3 0.3 -2.2 -2.5



IVS12-3T>A


Instruction: t93635383a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased93635385 0 93635385 8.5 5.9 -2.6 -5.916.8 -0.1 -0.7 -0.6
Sites found for donor
No Change 93635387 293635385 4.7 4.7 0.0 1.0100 -1.0 -1.0 0.0
No Change 93635396 1193635385 1.6 1.6 0.0 1.0100 -2.0 -2.0 0.0
No Change 93635405 2093635385 5.1 5.1 0.0 1.0100 -0.9 -0.9 0.0
No Change 93635423 3893635385 2.6 2.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93635431 4693635385 7.5 7.5 0.0 1.0100 -0.2 -0.2 0.0
Decreased93635382-393635385 5.1 -2.7 -7.8 -34.3NA -0.9 -3.3 -2.4



IVS13+4-+22delAGTATTGACTACTTCATTG


Instruction: d93635434,93635452 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Sites found for donor
No Change 93635387 -4493635431 4.7 4.7 0.0 1.0100 -1.0 -1.0 0.0
No Change 93635396 -3593635431 1.6 1.6 0.0 1.0100 -2.0 -2.0 0.0
No Change 93635405 -2693635431 5.1 5.1 0.0 1.0100 -0.9 -0.9 0.0
No Change 93635423 -893635431 2.6 2.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93635464 3393635431 0.8 0.8 0.0 1.0100 -2.2 -2.2 0.0
Decreased93635431093635431 7.5 -0.7 -8.2 -180.6NA -0.2 -2.6 -2.5
Decreased936354522193635431 3.1 -14.1 -17.2 -8.5NA -1.5 -6.7 -5.2



IVS16+1G>A


Instruction: g93636363a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93636336 -2793636363 9.0 9.0 0.0 1.0100 0.0 0.0 0.0
No Change 93636345 -1893636363 7.5 7.5 0.0 1.0100 -0.3 -0.3 0.0
Decreased93636362 -1 93636363 3.3 2.4 -1.0 -1.951.5 -1.2 -1.4 -0.2
Sites found for donor
No Change 93636346 -1793636363 3.7 3.7 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636375 1293636363 4.8 4.8 0.0 1.0100 -1.0 -1.0 0.0
No Change 93636410 4793636363 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
Decreased93636363093636363 7.5 -5.3 -12.8 -177.2NA -0.2 -4.1 -3.9



IVS16+1G>T


Instruction: g93636363t ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93636336 -2793636363 9.0 9.0 0.0 1.0100 0.0 0.0 0.0
No Change 93636345 -1893636363 7.5 7.5 0.0 1.0100 -0.3 -0.3 0.0
Decreased93636362 -1 93636363 3.3 1.1 -2.2 -4.721.4 -1.2 -1.7 -0.5
Sites found for donor
No Change 93636346 -1793636363 3.7 3.7 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636375 1293636363 4.8 4.8 0.0 1.0100 -1.0 -1.0 0.0
No Change 93636410 4793636363 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
Decreased93636363093636363 7.5 -0.3 -7.8 -177.2NA -0.2 -2.5 -2.4
increased93636362-193636363 -8.1 0.1 8.2 1.1105.0 -4.9 -2.4 2.5



IVS16+2T>C


Instruction: t93636364c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93636336 -2793636363 9.0 9.0 0.0 1.0100 0.0 0.0 0.0
No Change 93636345 -1893636363 7.5 7.5 0.0 1.0100 -0.3 -0.3 0.0
Decreased93636362 -1 93636363 3.3 2.4 -0.9 -1.952.2 -1.2 -1.4 -0.2
Sites found for donor
No Change 93636346 -1793636363 3.7 3.7 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636375 1293636363 4.8 4.8 0.0 1.0100 -1.0 -1.0 0.0
No Change 93636410 4793636363 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
Decreased93636363093636363 7.5 -0.0 -7.5 -177.2NA -0.2 -2.4 -2.3



IVS19-1G>C


Instruction: g93637780c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93637762 -1893637780 0.4 0.4 0.0 1.0100 -1.9 -1.9 0.0
No Change 93637808 2893637780 1.1 1.1 0.0 1.0100 -1.7 -1.7 0.0
Decreased93637780093637780 5.0 -2.3 -7.3 -32.7NA -0.8 -2.4 -1.6
Sites found for donor
No Change 93637744 -3693637780 1.4 1.4 0.0 1.0100 -2.0 -2.0 0.0
Increased 93637782 293637780 8.3 8.5 0.3 1.2120.0 0.1 0.2 0.1
No Change 93637809 2993637780 3.2 3.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93637818 3893637780 4.0 4.0 0.0 1.0100 -1.2 -1.2 0.0
No Change 93637827 4793637780 8.3 8.3 0.0 1.0100 0.1 0.1 0.0



IVS21+2-+40del


Instruction: d93638068,93638106 ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93638049 -1893638067 5.0 5.0 0.0 1.0100 -0.8 -0.8 0.0
Decreased936381033693638067 1.8 0.0 -1.8 -3.627.8 -1.5 0.0 1.5
Sites found for donor
Decreased93638067093638067 4.1 -6.9 -11.0 -17.6NA -1.2 -4.5 -3.3



IVS21+5G>A


Instruction: g93638071a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93638049 -1893638067 5.0 5.0 0.0 1.0100 -0.8 -0.8 0.0
No Change 93638103 3693638067 1.8 1.8 0.0 1.0100 -1.5 -1.5 0.0
Sites found for donor
Decreased93638067 0 93638067 4.1 0.6 -3.5 -11.58.7 -1.2 -2.2 -1.1



c.1404+1G>A.c.70+717A>G


Instruction: g93637148a.a93623357g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased93623381 -13767 93637148 5.2 4.8 -0.4 -1.376.5 -0.8 -0.9 -0.1
No Change 93623440 -1370893637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
No Change 93623465 -1368393637148 4.7 4.7 0.0 1.0100 -0.9 -0.9 0.0
No Change 93623644 -1350493637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93623650 -1349893637148 7.3 7.3 0.0 1.0100 -0.4 -0.4 0.0
No Change 93623663 -1348593637148 2.9 2.9 0.0 1.0100 -1.3 -1.3 0.0
No Change 93623679 -1346993637148 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
No Change 93623810 -1333893637148 4.1 4.1 0.0 1.0100 -1.0 -1.0 0.0
No Change 93623913 -1323593637148 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 93623917 -1323193637148 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
No Change 93623923 -1322593637148 10.7 10.7 0.0 1.0100 0.4 0.4 0.0
No Change 93623928 -1322093637148 1.0 1.0 0.0 1.0100 -1.7 -1.7 0.0
No Change 93624097 -1305193637148 3.8 3.8 0.0 1.0100 -1.1 -1.1 0.0
No Change 93624232 -1291693637148 1.3 1.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 93624275 -1287393637148 4.4 4.4 0.0 1.0100 -1.0 -1.0 0.0
No Change 93624305 -1284393637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93624349 -1279993637148 3.7 3.7 0.0 1.0100 -1.1 -1.1 0.0
No Change 93624394 -1275493637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93624473 -1267593637148 7.7 7.7 0.0 1.0100 -0.3 -0.3 0.0
No Change 93624549 -1259993637148 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 93624552 -1259693637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93624559 -1258993637148 6.2 6.2 0.0 1.0100 -0.6 -0.6 0.0
No Change 93624560 -1258893637148 9.5 9.5 0.0 1.0100 0.1 0.1 0.0
No Change 93624588 -1256093637148 3.6 3.6 0.0 1.0100 -1.1 -1.1 0.0
No Change 93624590 -1255893637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93624605 -1254393637148 1.9 1.9 0.0 1.0100 -1.5 -1.5 0.0
No Change 93624700 -1244893637148 3.6 3.6 0.0 1.0100 -1.1 -1.1 0.0
No Change 93624878 -1227093637148 2.4 2.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93624882 -1226693637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93624886 -1226293637148 9.5 9.5 0.0 1.0100 0.1 0.1 0.0
No Change 93624935 -1221393637148 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
No Change 93624947 -1220193637148 5.7 5.7 0.0 1.0100 -0.7 -0.7 0.0
No Change 93624971 -1217793637148 4.8 4.8 0.0 1.0100 -0.9 -0.9 0.0
No Change 93625003 -1214593637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93625025 -1212393637148 2.5 2.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 93625128 -1202093637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93625137 -1201193637148 5.9 5.9 0.0 1.0100 -0.7 -0.7 0.0
No Change 93625181 -1196793637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93625225 -1192393637148 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 93625241 -1190793637148 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 93625282 -1186693637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625283 -1186593637148 2.1 2.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93625284 -1186493637148 10.1 10.1 0.0 1.0100 0.3 0.3 0.0
No Change 93625286 -1186293637148 18.4 18.4 0.0 1.0100 2.1 2.1 0.0
No Change 93625292 -1185693637148 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
No Change 93625294 -1185493637148 4.9 4.9 0.0 1.0100 -0.9 -0.9 0.0
No Change 93625295 -1185393637148 4.3 4.3 0.0 1.0100 -1.0 -1.0 0.0
No Change 93625297 -1185193637148 2.1 2.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93625352 -1179693637148 7.5 7.5 0.0 1.0100 -0.3 -0.3 0.0
No Change 93625371 -1177793637148 4.4 4.4 0.0 1.0100 -1.0 -1.0 0.0
No Change 93625403 -1174593637148 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 93625412 -1173693637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93625459 -1168993637148 5.0 5.0 0.0 1.0100 -0.8 -0.8 0.0
No Change 93625487 -1166193637148 2.4 2.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93625570 -1157893637148 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 93625590 -1155893637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93625628 -1152093637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625641 -1150793637148 0.4 0.4 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625668 -1148093637148 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93625728 -1142093637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625731 -1141793637148 12.2 12.2 0.0 1.0100 0.7 0.7 0.0
No Change 93625775 -1137393637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
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No Change 93636375 -77393637148 4.8 4.8 0.0 1.0100 -1.0 -1.0 0.0
No Change 93636410 -73893637148 1.2 1.2 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636415 -73393637148 3.1 3.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93636431 -71793637148 0.2 0.2 0.0 1.0100 -2.4 -2.4 0.0
No Change 93636604 -54493637148 2.5 2.5 0.0 1.0100 -1.7 -1.7 0.0
No Change 93636608 -54093637148 0.2 0.2 0.0 1.0100 -2.4 -2.4 0.0
No Change 93636653 -49593637148 3.6 3.6 0.0 1.0100 -1.4 -1.4 0.0
No Change 93636658 -49093637148 1.6 1.6 0.0 1.0100 -1.9 -1.9 0.0
No Change 93636663 -48593637148 4.5 4.5 0.0 1.0100 -1.1 -1.1 0.0
No Change 93636666 -48293637148 1.3 1.3 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636694 -45493637148 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636699 -44993637148 1.3 1.3 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636726 -42293637148 1.8 1.8 0.0 1.0100 -1.9 -1.9 0.0
No Change 93636830 -31893637148 2.1 2.1 0.0 1.0100 -1.8 -1.8 0.0
No Change 93636862 -28693637148 4.2 4.2 0.0 1.0100 -1.1 -1.1 0.0
No Change 93636880 -26893637148 3.6 3.6 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636916 -23293637148 3.8 3.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636921 -22793637148 5.3 5.3 0.0 1.0100 -0.8 -0.8 0.0
No Change 93636960 -18893637148 7.4 7.4 0.0 1.0100 -0.2 -0.2 0.0
No Change 93636964 -18493637148 0.1 0.1 0.0 1.0100 -2.4 -2.4 0.0
No Change 93636991 -15793637148 1.1 1.1 0.0 1.0100 -2.1 -2.1 0.0
No Change 93637007 -14193637148 4.3 4.3 0.0 1.0100 -1.1 -1.1 0.0
No Change 93637012 -13693637148 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 93637104 -4493637148 4.7 4.7 0.0 1.0100 -1.0 -1.0 0.0
No Change 93637131 -1793637148 1.6 1.6 0.0 1.0100 -1.9 -1.9 0.0
No Change 93637140 -893637148 1.5 1.5 0.0 1.0100 -2.0 -2.0 0.0
No Change 93637173 2593637148 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
Decreased93637148093637148 5.8 -7.0 -12.8 -57.0NA -0.7 -4.6 -3.9
increased93623357-1379193637148 -3.1 9.7 12.8 808.680863.6 -3.4 0.5 3.9



c.1404+1G>C.c.540+5G>A


Instruction: g93637148c.g93625302a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93625282 -1186693637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625283 -1186593637148 2.1 2.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93625284 -1186493637148 10.1 10.1 0.0 1.0100 0.3 0.3 0.0
No Change 93625286 -1186293637148 18.4 18.4 0.0 1.0100 2.1 2.1 0.0
No Change 93625292 -1185693637148 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
No Change 93625294 -1185493637148 4.9 4.9 0.0 1.0100 -0.9 -0.9 0.0
No Change 93625295 -1185393637148 4.3 4.3 0.0 1.0100 -1.0 -1.0 0.0
No Change 93625297 -1185193637148 2.1 2.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93625352 -1179693637148 7.5 7.5 0.0 1.0100 -0.3 -0.3 0.0
No Change 93625371 -1177793637148 4.4 4.4 0.0 1.0100 -1.0 -1.0 0.0
No Change 93625403 -1174593637148 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 93625412 -1173693637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93625459 -1168993637148 5.0 5.0 0.0 1.0100 -0.8 -0.8 0.0
No Change 93625487 -1166193637148 2.4 2.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93625570 -1157893637148 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 93625590 -1155893637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93625628 -1152093637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625641 -1150793637148 0.4 0.4 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625668 -1148093637148 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93625728 -1142093637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93625731 -1141793637148 12.2 12.2 0.0 1.0100 0.7 0.7 0.0
No Change 93625775 -1137393637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
No Change 93625920 -1122893637148 12.0 12.0 0.0 1.0100 0.7 0.7 0.0
No Change 93625977 -1117193637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93626204 -1094493637148 4.6 4.6 0.0 1.0100 -0.9 -0.9 0.0
No Change 93626231 -1091793637148 2.1 2.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93626315 -1083393637148 4.4 4.4 0.0 1.0100 -1.0 -1.0 0.0
No Change 93626359 -1078993637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
No Change 93626390 -1075893637148 6.1 6.1 0.0 1.0100 -0.6 -0.6 0.0
No Change 93626483 -1066593637148 1.3 1.3 0.0 1.0100 -1.6 -1.6 0.0
No Change 93626516 -1063293637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93626536 -1061293637148 1.0 1.0 0.0 1.0100 -1.7 -1.7 0.0
No Change 93626551 -1059793637148 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 93626584 -1056493637148 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 93626587 -1056193637148 11.9 11.9 0.0 1.0100 0.7 0.7 0.0
No Change 93626594 -1055493637148 2.4 2.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93626690 -1045893637148 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 93626724 -1042493637148 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
No Change 93626748 -1040093637148 4.5 4.5 0.0 1.0100 -0.9 -0.9 0.0
No Change 93626762 -1038693637148 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
No Change 93626807 -1034193637148 4.5 4.5 0.0 1.0100 -1.0 -1.0 0.0
No Change 93626858 -1029093637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93626880 -1026893637148 1.9 1.9 0.0 1.0100 -1.5 -1.5 0.0
No Change 93626931 -1021793637148 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 93626946 -1020293637148 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 93626962 -1018693637148 0.0 0.0 0.0 1.0100 -1.9 -1.9 0.0
No Change 93626969 -1017993637148 4.0 4.0 0.0 1.0100 -1.1 -1.1 0.0
No Change 93626978 -1017093637148 2.5 2.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 93627178 -997093637148 4.8 4.8 0.0 1.0100 -0.9 -0.9 0.0
No Change 93627182 -996693637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627216 -993293637148 3.4 3.4 0.0 1.0100 -1.2 -1.2 0.0
No Change 93627222 -992693637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93627279 -986993637148 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627301 -984793637148 0.9 0.9 0.0 1.0100 -1.7 -1.7 0.0
No Change 93627325 -982393637148 1.9 1.9 0.0 1.0100 -1.5 -1.5 0.0
No Change 93627376 -977293637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93627380 -976893637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93627490 -965893637148 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627527 -962193637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93627578 -957093637148 4.4 4.4 0.0 1.0100 -1.0 -1.0 0.0
No Change 93627640 -950893637148 2.0 2.0 0.0 1.0100 -1.5 -1.5 0.0
No Change 93627644 -950493637148 5.1 5.1 0.0 1.0100 -0.8 -0.8 0.0
No Change 93627684 -946493637148 3.7 3.7 0.0 1.0100 -1.1 -1.1 0.0
No Change 93627694 -945493637148 8.5 8.5 0.0 1.0100 -0.1 -0.1 0.0
No Change 93627727 -942193637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93627729 -941993637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93627734 -941493637148 9.0 9.0 0.0 1.0100 0.0 0.0 0.0
No Change 93627744 -940493637148 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627753 -939593637148 2.9 2.9 0.0 1.0100 -1.3 -1.3 0.0
No Change 93627757 -939193637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627798 -935093637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93627807 -934193637148 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93627816 -933293637148 4.3 4.3 0.0 1.0100 -1.0 -1.0 0.0
No Change 93627858 -929093637148 3.8 3.8 0.0 1.0100 -1.1 -1.1 0.0
No Change 93627868 -928093637148 4.8 4.8 0.0 1.0100 -0.9 -0.9 0.0
No Change 93627902 -924693637148 2.3 2.3 0.0 1.0100 -1.4 -1.4 0.0
No Change 93627905 -924393637148 5.4 5.4 0.0 1.0100 -0.8 -0.8 0.0
No Change 93627910 -923893637148 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627958 -919093637148 0.7 0.7 0.0 1.0100 -1.8 -1.8 0.0
No Change 93627968 -918093637148 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93627972 -917693637148 4.6 4.6 0.0 1.0100 -0.9 -0.9 0.0
No Change 93627973 -917593637148 9.5 9.5 0.0 1.0100 0.1 0.1 0.0
No Change 93628001 -914793637148 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 93628017 -913193637148 8.1 8.1 0.0 1.0100 -0.2 -0.2 0.0
No Change 93628041 -910793637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93628078 -907093637148 3.9 3.9 0.0 1.0100 -1.1 -1.1 0.0
No Change 93628097 -905193637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93628101 -904793637148 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 93628213 -893593637148 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
No Change 93628218 -893093637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93628221 -892793637148 6.2 6.2 0.0 1.0100 -0.6 -0.6 0.0
No Change 93628308 -884093637148 0.4 0.4 0.0 1.0100 -1.9 -1.9 0.0
No Change 93628318 -883093637148 8.7 8.7 0.0 1.0100 -0.0 -0.0 0.0
No Change 93628324 -882493637148 3.8 3.8 0.0 1.0100 -1.1 -1.1 0.0
No Change 93628365 -878393637148 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
No Change 93628464 -868493637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93628466 -868293637148 6.4 6.4 0.0 1.0100 -0.5 -0.5 0.0
No Change 93628521 -862793637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93628580 -856893637148 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93628596 -855293637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93628597 -855193637148 5.0 5.0 0.0 1.0100 -0.8 -0.8 0.0
No Change 93628626 -852293637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93628651 -849793637148 2.7 2.7 0.0 1.0100 -1.4 -1.4 0.0
No Change 93628660 -848893637148 7.2 7.2 0.0 1.0100 -0.4 -0.4 0.0
No Change 93628692 -845693637148 4.5 4.5 0.0 1.0100 -1.0 -1.0 0.0
No Change 93628697 -845193637148 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 93628759 -838993637148 6.9 6.9 0.0 1.0100 -0.4 -0.4 0.0
No Change 93628804 -834493637148 7.3 7.3 0.0 1.0100 -0.3 -0.3 0.0
No Change 93628806 -834293637148 2.5 2.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 93628809 -833993637148 3.7 3.7 0.0 1.0100 -1.1 -1.1 0.0
No Change 93628811 -833793637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93628892 -825693637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93628920 -822893637148 3.2 3.2 0.0 1.0100 -1.2 -1.2 0.0
No Change 93628937 -821193637148 4.5 4.5 0.0 1.0100 -1.0 -1.0 0.0
No Change 93628945 -820393637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93628955 -819393637148 1.9 1.9 0.0 1.0100 -1.5 -1.5 0.0
No Change 93629009 -813993637148 2.4 2.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93629097 -805193637148 2.8 2.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 93629104 -804493637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93629105 -804393637148 13.9 13.9 0.0 1.0100 1.1 1.1 0.0
No Change 93629107 -804193637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93629108 -804093637148 0.9 0.9 0.0 1.0100 -1.7 -1.7 0.0
No Change 93629115 -803393637148 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
No Change 93629120 -802893637148 4.9 4.9 0.0 1.0100 -0.9 -0.9 0.0
No Change 93629182 -796693637148 5.0 5.0 0.0 1.0100 -0.8 -0.8 0.0
No Change 93629231 -791793637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93629244 -790493637148 4.0 4.0 0.0 1.0100 -1.1 -1.1 0.0
No Change 93629253 -789593637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93629271 -787793637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93629302 -784693637148 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
No Change 93629344 -780493637148 2.4 2.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93629347 -780193637148 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
No Change 93629406 -774293637148 2.3 2.3 0.0 1.0100 -1.4 -1.4 0.0
No Change 93629410 -773893637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93629531 -761793637148 3.8 3.8 0.0 1.0100 -1.1 -1.1 0.0
No Change 93629540 -760893637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93629618 -753093637148 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
No Change 93629662 -748693637148 2.1 2.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93629670 -747893637148 5.4 5.4 0.0 1.0100 -0.8 -0.8 0.0
No Change 93629747 -740193637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93629778 -737093637148 3.9 3.9 0.0 1.0100 -1.1 -1.1 0.0
No Change 93629867 -728193637148 1.3 1.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 93629868 -728093637148 5.9 5.9 0.0 1.0100 -0.6 -0.6 0.0
No Change 93629871 -727793637148 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 93629901 -724793637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93629936 -721293637148 1.5 1.5 0.0 1.0100 -1.6 -1.6 0.0
No Change 93629943 -720593637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93629953 -719593637148 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 93629993 -715593637148 2.7 2.7 0.0 1.0100 -1.3 -1.3 0.0
No Change 93630022 -712693637148 2.2 2.2 0.0 1.0100 -1.5 -1.5 0.0
No Change 93630220 -692893637148 0.6 0.6 0.0 1.0100 -1.8 -1.8 0.0
No Change 93630280 -686893637148 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 93630298 -685093637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93630336 -681293637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93630359 -678993637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93630362 -678693637148 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
No Change 93630365 -678393637148 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93630501 -664793637148 3.0 3.0 0.0 1.0100 -1.3 -1.3 0.0
No Change 93630502 -664693637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93630505 -664393637148 8.7 8.7 0.0 1.0100 -0.0 -0.0 0.0
No Change 93630566 -658293637148 2.3 2.3 0.0 1.0100 -1.4 -1.4 0.0
No Change 93630590 -655893637148 2.3 2.3 0.0 1.0100 -1.4 -1.4 0.0
No Change 93630637 -651193637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93630786 -636293637148 0.9 0.9 0.0 1.0100 -1.8 -1.8 0.0
No Change 93630863 -628593637148 3.1 3.1 0.0 1.0100 -1.3 -1.3 0.0
No Change 93630934 -621493637148 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
No Change 93631123 -602593637148 4.9 4.9 0.0 1.0100 -0.9 -0.9 0.0
No Change 93631125 -602393637148 0.3 0.3 0.0 1.0100 -1.9 -1.9 0.0
No Change 93631205 -594393637148 7.8 7.8 0.0 1.0100 -0.2 -0.2 0.0
No Change 93631217 -593193637148 1.4 1.4 0.0 1.0100 -1.6 -1.6 0.0
No Change 93631237 -591193637148 1.3 1.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 93631248 -590093637148 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93631335 -581393637148 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93631422 -572693637148 1.0 1.0 0.0 1.0100 -1.7 -1.7 0.0
No Change 93631500 -564893637148 3.4 3.4 0.0 1.0100 -1.2 -1.2 0.0
No Change 93631503 -564593637148 1.0 1.0 0.0 1.0100 -1.7 -1.7 0.0
No Change 93631535 -561393637148 3.9 3.9 0.0 1.0100 -1.1 -1.1 0.0
No Change 93631542 -560693637148 3.4 3.4 0.0 1.0100 -1.2 -1.2 0.0
No Change 93631545 -560393637148 2.9 2.9 0.0 1.0100 -1.3 -1.3 0.0
No Change 93631547 -560193637148 1.8 1.8 0.0 1.0100 -1.6 -1.6 0.0
No Change 93631551 -559793637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93631573 -557593637148 5.5 5.5 0.0 1.0100 -0.7 -0.7 0.0
No Change 93631590 -555893637148 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
No Change 93631632 -551693637148 3.4 3.4 0.0 1.0100 -1.2 -1.2 0.0
No Change 93631635 -551393637148 1.1 1.1 0.0 1.0100 -1.7 -1.7 0.0
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No Change 93636663 -48593637148 4.5 4.5 0.0 1.0100 -1.1 -1.1 0.0
No Change 93636666 -48293637148 1.3 1.3 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636694 -45493637148 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636699 -44993637148 1.3 1.3 0.0 1.0100 -2.1 -2.1 0.0
No Change 93636726 -42293637148 1.8 1.8 0.0 1.0100 -1.9 -1.9 0.0
No Change 93636830 -31893637148 2.1 2.1 0.0 1.0100 -1.8 -1.8 0.0
No Change 93636862 -28693637148 4.2 4.2 0.0 1.0100 -1.1 -1.1 0.0
No Change 93636880 -26893637148 3.6 3.6 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636916 -23293637148 3.8 3.8 0.0 1.0100 -1.3 -1.3 0.0
No Change 93636921 -22793637148 5.3 5.3 0.0 1.0100 -0.8 -0.8 0.0
No Change 93636960 -18893637148 7.4 7.4 0.0 1.0100 -0.2 -0.2 0.0
No Change 93636964 -18493637148 0.1 0.1 0.0 1.0100 -2.4 -2.4 0.0
No Change 93636991 -15793637148 1.1 1.1 0.0 1.0100 -2.1 -2.1 0.0
No Change 93637007 -14193637148 4.3 4.3 0.0 1.0100 -1.1 -1.1 0.0
No Change 93637012 -13693637148 2.3 2.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 93637104 -4493637148 4.7 4.7 0.0 1.0100 -1.0 -1.0 0.0
No Change 93637131 -1793637148 1.6 1.6 0.0 1.0100 -1.9 -1.9 0.0
No Change 93637140 -893637148 1.5 1.5 0.0 1.0100 -2.0 -2.0 0.0
No Change 93637173 2593637148 0.4 0.4 0.0 1.0100 -2.3 -2.3 0.0
Decreased93625302-1184693637148 0.5 -12.3 -12.8 -1.4NA -2.3 -6.2 -3.9
Decreased93637148093637148 5.8 -4.0 -9.8 -57.0NA -0.7 -3.6 -3.0



IVS26+3A>G


Instruction: a93640678g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Decreased93640697 21 93640676 1.8 1.6 -0.2 -1.187.8 -1.6 -1.6 -0.0
No Change 93640711 3593640676 1.0 1.0 0.0 1.0100 -1.7 -1.7 0.0
No Change 93640723 4793640676 1.2 1.2 0.0 1.0100 -1.7 -1.7 0.0
Decreased93640679393640676 1.8 -6.4 -8.2 -3.4NA -1.6 -3.3 -1.8
Sites found for donor
No Change 93640641 -3593640676 4.6 4.6 0.0 1.0100 -1.0 -1.0 0.0
No Change 93640650 -2693640676 2.4 2.4 0.0 1.0100 -1.7 -1.7 0.0
No Change 93640668 -893640676 2.2 2.2 0.0 1.0100 -1.8 -1.8 0.0
Decreased93640676 0 93640676 8.3 7.9 -0.4 -1.375.7 0.1 -0.0 -0.1
Decreased93640680493640676 2.2 -0.1 -2.3 -4.5NA -1.8 -2.5 -0.7



IVS27-2A>G


Instruction: a93641431g ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93641422 -1093641432 2.6 2.6 0.0 1.0100 -1.4 -1.4 0.0
No Change 93641426 -693641432 3.5 3.5 0.0 1.0100 -1.2 -1.2 0.0
Decreased93641432 0 93641432 13.1 4.9 -8.2 -286.20.3 0.9 -0.9 -1.8
Decreased93641433 1 93641432 1.8 0.0 -1.7 -3.329.8 -1.6 -1.9 -0.4
Increased 93641442 1093641432 2.7 3.1 0.3 1.3125.6 -1.3 -1.3 0.1
No Change 93641478 4693641432 7.7 7.7 0.0 1.0100 -0.3 -0.3 0.0
increased93641431-193641432 -3.5 4.0 7.6 16.41643.1 -2.7 -1.1 1.7
Sites found for donor
No Change 93641389 -4393641432 3.0 3.0 0.0 1.0100 -1.5 -1.5 0.0
Decreased93641434 2 93641432 1.5 0.5 -1.0 -2.049.9 -2.0 -2.3 -0.3
No Change 93641443 1193641432 4.5 4.5 0.0 1.0100 -1.1 -1.1 0.0
No Change 93641452 2093641432 7.2 7.2 0.0 1.0100 -0.2 -0.2 0.0



IVS32+1G>A


Instruction: g93645371a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93645411 4093645371 0.8 0.8 0.0 1.0100 -1.8 -1.8 0.0
Sites found for donor
No Change 93645327 -4493645371 3.4 3.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93645336 -3593645371 0.5 0.5 0.0 1.0100 -2.3 -2.3 0.0
No Change 93645357 -1493645371 3.3 3.3 0.0 1.0100 -1.4 -1.4 0.0
No Change 93645411 4093645371 2.8 2.8 0.0 1.0100 -1.6 -1.6 0.0
Decreased93645371093645371 9.9 -2.9 -12.8 -960.7NA 0.6 -3.3 -3.9



IVS33+4G>A


Sequence Walker
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Unprocessed due to the following error. IVS33+4G>A the old base at 93646095 is NOT g! It is a.



IVS33+5G>A


Instruction: g93646096a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93646125 3393646092 1.7 1.7 0.0 1.0100 -1.6 -1.6 0.0
No Change 93646128 3693646092 1.3 1.3 0.0 1.0100 -1.7 -1.7 0.0
No Change 93646142 5093646092 2.5 2.5 0.0 1.0100 -1.4 -1.4 0.0
No Change 93646143 5193646092 0.1 0.1 0.0 1.0100 -1.9 -1.9 0.0
No Change 93646147 5593646092 0.5 0.5 0.0 1.0100 -1.8 -1.8 0.0
Sites found for donor
No Change 93646057 -3593646092 5.5 5.5 0.0 1.0100 -0.8 -0.8 0.0
No Change 93646066 -2693646092 3.4 3.4 0.0 1.0100 -1.4 -1.4 0.0
No Change 93646084 -893646092 2.0 2.0 0.0 1.0100 -1.8 -1.8 0.0
Decreased93646090 -2 93646092 1.9 1.5 -0.4 -1.375.8 -1.9 -2.0 -0.1
Decreased93646092 0 93646092 6.7 3.2 -3.5 -11.58.7 -0.4 -1.5 -1.1
No Change 93646110 1893646092 2.1 2.1 0.0 1.0100 -1.8 -1.8 0.0



IVS40+5G>A


Instruction: g93650662a ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
Increased 93650686 2893650658 0.3 0.7 0.4 1.3130.5 -1.9 -1.8 0.1
No Change 93650689 3193650658 1.6 1.6 0.0 1.0100 -1.6 -1.6 0.0
No Change 93650694 3693650658 0.2 0.2 0.0 1.0100 -1.9 -1.9 0.0
No Change 93650698 4093650658 1.0 1.0 0.0 1.0100 -1.7 -1.7 0.0
Sites found for donor
No Change 93650623 -3593650658 8.6 8.6 0.0 1.0100 0.2 0.2 0.0
No Change 93650641 -1793650658 1.0 1.0 0.0 1.0100 -2.1 -2.1 0.0
No Change 93650650 -893650658 2.2 2.2 0.0 1.0100 -1.8 -1.8 0.0
Decreased93650658 0 93650658 6.6 3.1 -3.5 -11.58.7 -0.4 -1.5 -1.1
Decreased93650662493650658 3.2 -9.6 -12.8 -9.4NA -1.5 -5.3 -3.9



IVS46+2T>C


Instruction: t93654071c ; Sequence Walker  
Type of changeGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
Sites found for acceptor
No Change 93654120 5093654070 1.1 1.1 0.0 1.0100 -1.7 -1.7 0.0
Sites found for donor
No Change 93654053 -1793654070 3.1 3.1 0.0 1.0100 -1.5 -1.5 0.0
No Change 93654062 -893654070 2.1 2.1 0.0 1.0100 -1.8 -1.8 0.0
Increased 93654074 493654070 2.6 4.2 1.6 3.0303.1 -1.6 -1.2 0.5
Decreased93654070093654070 6.2 -1.2 -7.5 -75.2NA -0.5 -2.8 -2.3