Gene: COL1A2
mRNA Accession: J03464
Mutation:COL1A2.txt
Chromosome: chr 7

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS12+2T>G
Sequence Walker
t93633844g 93633842 -1 93633843 0.5 0.0 -0.5 -1.4 70.0 -1.8 -1.9 -0.1
IVS12-3T>A
Sequence Walker
t93635383a 93635385 0 93635385 8.5 5.9 -2.6 -5.9 16.8 -0.1 -0.7 -0.6
IVS16+1G>A
Sequence Walker
g93636363a 93636362 -1 93636363 3.3 2.4 -1.0 -1.9 51.5 -1.2 -1.4 -0.2
IVS16+1G>T
Sequence Walker
g93636363t 93636362 -1 93636363 3.3 1.1 -2.2 -4.7 21.4 -1.2 -1.7 -0.5
IVS16+2T>C
Sequence Walker
t93636364c 93636362 -1 93636363 3.3 2.4 -0.9 -1.9 52.2 -1.2 -1.4 -0.2
IVS19-1G>C
Sequence Walker  
g93637780c 93637780 0 93637780 5.0 -2.3 -7.3 -32.7 NA -0.8 -2.4 -1.6
IVS21+2-+40del
Sequence Walker  
d93638068,93638106 93638103 36 93638067 1.8 0.0 -1.8 -3.6 27.8 -1.5 0.0 1.5
IVS26+3A>G
Sequence Walker
a93640678g 93640697 21 93640676 1.8 1.6 -0.2 -1.1 87.8 -1.6 -1.6 -0.0
IVS26+3A>G
Sequence Walker  
a93640678g 93640679 3 93640676 1.8 -6.4 -8.2 -3.4 NA -1.6 -3.3 -1.8
IVS27-2A>G
Sequence Walker
a93641431g 93641432 0 93641432 13.1 4.9 -8.2 -286.2 0.3 0.9 -0.9 -1.8
IVS27-2A>G
Sequence Walker
a93641431g 93641433 1 93641432 1.8 0.0 -1.7 -3.3 29.8 -1.6 -1.9 -0.4
IVS5-1G>A
Sequence Walker
g93629105a 93629104 -1 93629105 1.5 0.6 -1.0 -1.9 51.5 -1.6 -1.8 -0.2
IVS5-1G>A
Sequence Walker
g93629105a 93629105 0 93629105 13.9 6.3 -7.6 -191.1 0.5 1.1 -0.6 -1.7
IVS5-1G>A
Sequence Walker
g93629105a 93629108 3 93629105 0.9 0.8 -0.1 -1.1 91.2 -1.7 -1.8 -0.0
IVS5-1G>A
Sequence Walker
g93629105a 93629115 10 93629105 0.5 0.1 -0.4 -1.4 73.8 -1.8 -1.9 -0.1
IVS5-1G>A
Sequence Walker
g93629105a 93629120 15 93629105 4.9 4.7 -0.2 -1.2 85.8 -0.9 -0.9 -0.0
IVS5-1G>C
Sequence Walker
g93629105c 93629105 0 93629105 13.9 6.6 -7.3 -156.4 0.6 1.1 -0.5 -1.6
IVS5-1G>C
Sequence Walker  
g93629105c 93629104 -1 93629105 1.5 -0.4 -1.9 -2.8 NA -1.6 -2.0 -0.4
IVS5-2A>G
Sequence Walker
a93629104g 93629105 0 93629105 13.9 5.7 -8.2 -286.2 0.3 1.1 -0.7 -1.8
IVS5-2A>G
Sequence Walker
a93629104g 93629108 3 93629105 0.9 0.6 -0.3 -1.2 81.1 -1.7 -1.8 -0.1
IVS6+2T>C
Sequence Walker
t93629161c 93629182 22 93629160 5.0 5.0 -0.1 -1.0 96.1 -0.8 -0.9 -0.0
IVS9+3-+13delAAGTATTTACT
Sequence Walker  
d93632434,93632444 93632450 18 93632432 0.2 -9.6 -9.8 -1.2 NA -1.9 -4.0 -2.1
IVS9+5G>A
Sequence Walker  
g93632436a 93632450 18 93632432 0.2 -0.1 -0.3 -1.2 NA -1.9 -2.0 -0.1
c.1404+1G>A.c.70+717A>G
Sequence Walker
g93637148a.a93623357g 93623381 -13767 93637148 5.2 4.8 -0.4 -1.3 76.5 -0.8 -0.9 -0.1