Gene: COL1A1
mRNA Accession: Z74615
Mutation:COL1A1.txt
Chromosome: chr 17

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS22-1G>T
Sequence Walker  
c48613888a 48613905 -17 48613888 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
IVS22-1G>T
Sequence Walker  
c48613888a 48613877 11 48613888 5.7 5.7 0.0 1.0 100 -0.7 -0.7 0.0
IVS22-1G>T
Sequence Walker  
c48613888a 48613871 17 48613888 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS22+3A>G
Sequence Walker  
t48614010c 48614056 -44 48614012 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
IVS22+3A>G
Sequence Walker  
t48614010c 48614029 -17 48614012 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS25-1G>A
Sequence Walker  
c48612488t 48612477 11 48612488 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS25-1G>A
Sequence Walker  
c48612488t 48612468 20 48612488 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS25-1G>A
Sequence Walker  
c48612488t 48612459 29 48612488 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
IVS26+1G>A
Sequence Walker  
c48612433t 48612477 -44 48612433 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS26+1G>A
Sequence Walker  
c48612433t 48612468 -35 48612433 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS26+1G>A
Sequence Walker  
c48612433t 48612459 -26 48612433 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
IVS26+1G>A
Sequence Walker  
c48612433t 48612429 4 48612433 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
IVS26+1G>T
Sequence Walker  
c48612433a 48612477 -44 48612433 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS26+1G>T
Sequence Walker  
c48612433a 48612468 -35 48612433 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS26+1G>T
Sequence Walker  
c48612433a 48612459 -26 48612433 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
IVS26+1G>T
Sequence Walker  
c48612433a 48612429 4 48612433 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
IVS26-2A>C
Sequence Walker  
t48612292g 48612271 20 48612291 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
IVS27-1G>C
Sequence Walker  
c48612134g 48612159 -25 48612134 2.7 2.7 0.0 1.0 100 -1.6 -1.6 0.0
IVS27-1G>C
Sequence Walker  
c48612134g 48612123 11 48612134 1.6 1.6 0.0 1.0 100 -2.0 -2.0 0.0
IVS27-1G>C
Sequence Walker  
c48612134g 48612114 20 48612134 6.2 6.2 0.0 1.0 100 -0.5 -0.5 0.0
IVS41+4A>C
Sequence Walker  
t48608339g 48608359 -17 48608342 6.5 6.5 0.0 1.0 100 -0.5 -0.5 0.0
IVS41+4A>C
Sequence Walker  
t48608339g 48608347 -5 48608342 5.4 5.4 0.0 1.0 100 -0.8 -0.8 0.0
IVS47+1G>A
Sequence Walker  
c48606454t 48606471 -17 48606454 4.9 4.9 0.0 1.0 100 -1.0 -1.0 0.0
IVS47-3C>G
Sequence Walker  
g48606365c 48606393 -30 48606363 5.2 5.2 0.0 1.0 100 -0.9 -0.9 0.0
IVS12+1G>A
Sequence Walker  
c48616056t 48616100 -44 48616056 0.6 0.6 0.0 1.0 100 -2.2 -2.2 0.0
IVS12+1G>A
Sequence Walker  
c48616056t 48616091 -35 48616056 1.4 1.4 0.0 1.0 100 -2.0 -2.0 0.0
IVS13-10T>A
Sequence Walker  
a48615817t 48615812 -4 48615808 0.5 0.5 0.0 1.0 100 -2.3 -2.3 0.0
IVS13-10T>A
Sequence Walker  
a48615817t 48615788 20 48615808 9.0 9.0 0.0 1.0 100 0.3 0.3 0.0
IVS14+5G>A
Sequence Walker  
c48615749t 48615788 -35 48615753 9.0 9.0 0.0 1.0 100 0.3 0.3 0.0
IVS15-33--44delCTGCCATCTCTT
Sequence Walker  
d48615661,48615672 48615638 2 48615640 1.9 1.9 0.0 1.0 100 -1.9 -1.9 0.0
IVS16-2A>G
Sequence Walker  
t48615107c 48615158 -52 48615106 2.3 2.3 0.0 1.0 100 -1.7 -1.7 0.0
IVS16-2A>G
Sequence Walker  
t48615107c 48615153 -47 48615106 3.8 3.8 0.0 1.0 100 -1.3 -1.3 0.0
IVS16-2A>G
Sequence Walker  
t48615107c 48615138 -32 48615106 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
IVS16-2A>G
Sequence Walker  
t48615107c 48615059 47 48615106 5.8 5.8 0.0 1.0 100 -0.7 -0.7 0.0
IVS17+1G>C
Sequence Walker  
c48615006g 48615057 -51 48615006 2.9 2.9 0.0 1.0 100 -1.6 -1.6 0.0
IVS17+1G>C
Sequence Walker  
c48615006g 48615050 -44 48615006 7.4 7.4 0.0 1.0 100 -0.2 -0.2 0.0
IVS17+1G>C
Sequence Walker  
c48615006g 48615023 -17 48615006 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS18+1G>A
Sequence Walker  
c48614873t 48614908 -35 48614873 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
IVS18+1G>A
Sequence Walker  
c48614873t 48614890 -17 48614873 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS18+1G>A
Sequence Walker  
c48614873t 48614881 -8 48614873 3.6 3.6 0.0 1.0 100 -1.3 -1.3 0.0
IVS18-1G>A
Sequence Walker  
c48614771t 48614760 11 48614771 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
IVS18-1G>A
Sequence Walker  
c48614771t 48614751 20 48614771 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS18-1G>A
Sequence Walker  
c48614771t 48614733 38 48614771 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
IVS19+1G>A
Sequence Walker  
c48614671t 48614679 -8 48614671 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0
IVS19+1G>A
Sequence Walker  
c48614671t 48614625 46 48614671 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
IVS19+1G>C
Sequence Walker  
c48614671g 48614679 -8 48614671 5.1 5.1 0.0 1.0 100 -0.9 -0.9 0.0
IVS19+1G>C
Sequence Walker  
c48614671g 48614625 46 48614671 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0
IVS20+2T>C
Sequence Walker  
a48614485g 48614530 -44 48614486 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS20+2T>C
Sequence Walker  
a48614485g 48614503 -17 48614486 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
IVS20+2T>C
Sequence Walker  
a48614485g 48614494 -8 48614486 0.5 0.5 0.0 1.0 100 -2.3 -2.3 0.0
IVS20-2A>G
Sequence Walker  
t48614270c 48614262 7 48614269 0.7 0.7 0.0 1.0 100 -2.2 -2.2 0.0
IVS20-2A>G
Sequence Walker  
t48614270c 48614258 11 48614269 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
IVS20-2A>G
Sequence Walker  
t48614270c 48614231 38 48614269 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0
IVS20-2A>G
Sequence Walker  
t48614270c 48614222 47 48614269 3.8 3.8 0.0 1.0 100 -1.3 -1.3 0.0
IVS3+1G>C
Sequence Walker  
c48618995g 48618957 38 48618995 2.1 2.1 0.0 1.0 100 -1.8 -1.8 0.0
IVS8+1G>C
Sequence Walker  
c48617388g 48617414 -26 48617388 8.6 8.6 0.0 1.0 100 0.2 0.2 0.0
IVS8+1G>C
Sequence Walker  
c48617388g 48617405 -17 48617388 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
IVS9-1G>T
Sequence Walker  
c48616674a 48616718 -44 48616674 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
IVS9-1G>T
Sequence Walker  
c48616674a 48616715 -41 48616674 5.3 5.3 0.0 1.0 100 -0.8 -0.8 0.0
IVS9-1G>T
Sequence Walker  
c48616674a 48616645 29 48616674 9.2 9.2 0.0 1.0 100 0.4 0.4 0.0
IVS9-1G>T
Sequence Walker  
c48616674a 48616639 35 48616674 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
c.1299+1G>C
Sequence Walker  
c48614873g 48614908 -35 48614873 2.0 2.0 0.0 1.0 100 -1.8 -1.8 0.0
c.1299+1G>C
Sequence Walker  
c48614873g 48614890 -17 48614873 1.6 1.6 0.0 1.0 100 -1.9 -1.9 0.0
c.1299+1G>C
Sequence Walker  
c48614873g 48614881 -8 48614873 3.6 3.6 0.0 1.0 100 -1.3 -1.3 0.0
c.333G>T;.c333+1G>C
Sequence Walker  
c48619277a.c48619192g 48619294 -102 48619192 1.3 1.3 0.0 1.0 100 -2.0 -2.0 0.0
c.333G>T;.c333+1G>C
Sequence Walker  
c48619277a.c48619192g 48619289 -97 48619192 3.4 3.4 0.0 1.0 100 -1.4 -1.4 0.0
c.333G>T;.c333+1G>C
Sequence Walker  
c48619277a.c48619192g 48619284 -92 48619192 0.5 0.5 0.0 1.0 100 -2.3 -2.3 0.0
c.333G>T;.c333+1G>C
Sequence Walker  
c48619277a.c48619192g 48619267 -75 48619192 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
c.333G>T;.c333+1G>C
Sequence Walker  
c48619277a.c48619192g 48619225 -33 48619192 2.8 2.8 0.0 1.0 100 -1.6 -1.6 0.0