Gene: COL1A1
mRNA Accession: Z74615
Mutation:COL1A1.txt
Chromosome: chr 17

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS22+3A>G
Sequence Walker
t48614010c 48614012 0 48614012 6.7 6.3 -0.4 -1.3 75.7 -0.4 -0.5 -0.1
IVS26+1G>A
Sequence Walker  
c48612433t 48612433 0 48612433 5.4 -7.4 -12.8 -42.4 NA -0.8 -4.7 -3.9
IVS26+1G>T
Sequence Walker  
c48612433a 48612433 0 48612433 5.4 -2.4 -7.8 -42.4 NA -0.8 -3.2 -2.4
IVS41+4A>C
Sequence Walker
t48608339g 48608342 0 48608342 9.8 6.7 -3.1 -8.4 11.9 0.5 -0.4 -0.9
IVS47+1G>A
Sequence Walker  
c48606454t 48606454 0 48606454 3.0 -9.8 -12.8 -8.2 NA -1.5 -5.4 -3.9
IVS48+1G>A
Sequence Walker  
c48606079t 48606079 0 48606079 8.2 -4.6 -12.8 -299.8 NA 0.1 -3.8 -3.9
IVS11+3-+6delGAGT
Sequence Walker  
d48616444,48616447 48616449 0 48616449 6.6 -10.7 -17.3 -98.2 NA -0.4 -5.7 -5.3
IVS12+1G>A
Sequence Walker  
c48616056t 48616056 0 48616056 11.4 -1.4 -12.8 -2677.4 NA 1.0 -2.9 -3.9
IVS14+5G>A
Sequence Walker
c48615749t 48615753 0 48615753 6.2 2.7 -3.5 -11.5 8.7 -0.5 -1.6 -1.1
IVS16-2A>G
Sequence Walker
t48615107c 48615104 2 48615106 4.9 3.9 -1.0 -2.0 49.9 -0.9 -1.2 -0.3
IVS17+1G>C
Sequence Walker  
c48615006g 48615006 0 48615006 6.6 -3.2 -9.8 -99.1 NA -0.4 -3.4 -3.0
IVS18+1G>A
Sequence Walker  
c48614873t 48614873 0 48614873 9.3 -3.5 -12.8 -613.6 NA 0.4 -3.5 -3.9
IVS19+1G>A
Sequence Walker  
c48614671t 48614671 0 48614671 5.8 -7.0 -12.8 -57.3 NA -0.7 -4.6 -3.9
IVS19+1G>C
Sequence Walker  
c48614671g 48614671 0 48614671 5.8 -4.0 -9.8 -57.3 NA -0.7 -3.6 -3.0
IVS20+2T>C
Sequence Walker  
a48614485g 48614486 0 48614486 7.2 -0.3 -7.5 -145.0 NA -0.3 -2.5 -2.3
IVS3+1G>C
Sequence Walker  
c48618995g 48618995 0 48618995 5.7 -4.1 -9.8 -52.2 NA -0.7 -3.7 -3.0
IVS8+1G>C
Sequence Walker  
c48617388g 48617388 0 48617388 4.6 -5.2 -9.8 -24.9 NA -1.0 -4.0 -3.0
c.1299+1G>C
Sequence Walker  
c48614873g 48614873 0 48614873 9.3 -0.5 -9.8 -613.6 NA 0.4 -2.6 -3.0
c.333G>T;.c333+1G>C
Sequence Walker
c48619277a.c48619192g 48619274 -82 48619192 1.3 0.8 -0.4 -1.4 73.7 -2.1 -2.2 -0.1
c.333G>T;.c333+1G>C
Sequence Walker  
c48619277a.c48619192g 48619192 0 48619192 7.8 -2.0 -9.8 -227.8 NA -0.1 -3.0 -3.0