Gene: COL1A1
mRNA Accession: Z74615
Mutation:COL1A1.txt
Chromosome: chr 17

Sequence Walker  


Information Increased
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS25-1G>A
Sequence Walker  
c48612488t 48612490 -2 48612488 5.0 5.1 0.0 1.0 103.1 -0.8 -0.8 0.0
IVS25-1G>A
Sequence Walker  
c48612488t 48612487 1 48612488 0.0 8.2 8.2 286.2 28616.6 -1.9 -0.1 1.8
IVS25-1G>A
Sequence Walker  
c48612488t 48612484 4 48612488 2.2 2.5 0.3 1.2 123.3 -1.4 -1.4 0.1
IVS26+1G>A
Sequence Walker  
c48612433t 48612409 24 48612433 2.0 2.4 0.4 1.3 130.5 -1.5 -1.4 0.1
IVS26+1G>T
Sequence Walker  
c48612433a 48612409 24 48612433 2.0 2.9 0.8 1.8 179.6 -1.5 -1.3 0.2
IVS26+1G>T
Sequence Walker  
c48612433a 48612429 4 48612433 -2.0 1.1 3.1 2.2 219.3 -2.4 -1.7 0.7
IVS26-2A>C
Sequence Walker  
t48612292g 48612290 1 48612291 1.3 5.5 4.2 18.7 1870.1 -1.7 -0.7 0.9
IVS26-2A>C
Sequence Walker  
t48612292g 48612281 10 48612291 -0.6 1.5 2.0 2.8 280.8 -2.1 -1.6 0.4
IVS26-2A>C
Sequence Walker  
t48612292g 48612275 16 48612291 -0.2 1.0 1.2 2.0 196.5 -2.0 -1.7 0.3
IVS41+4A>C
Sequence Walker  
t48608339g 48608316 26 48608342 1.7 2.2 0.5 1.4 143.5 -1.6 -1.4 0.1
IVS47+1G>A
Sequence Walker  
c48606454t 48606431 23 48606454 0.9 1.2 0.3 1.2 124.0 -1.7 -1.7 0.1
IVS47-3C>G
Sequence Walker  
g48606365c 48606366 -3 48606363 -0.2 1.7 1.9 3.3 333.4 -2.0 -1.6 0.4
IVS47-3C>G
Sequence Walker  
g48606365c 48606365 -2 48606363 -1.4 5.9 7.3 59.0 5899.3 -2.2 -0.7 1.6
IVS11+3-+6delGAGT
Sequence Walker  
d48616444,48616447 48616425 24 48616449 0.1 0.5 0.3 1.3 125.1 -1.9 -1.8 0.1
IVS13-10T>A
Sequence Walker  
a48615817t 48615816 -8 48615808 -0.3 7.1 7.4 140.1 14005.3 -2.0 -0.4 1.6
IVS15-33--44delCTGCCATCTCTT
Sequence Walker  
d48615661,48615672 48615640 0 48615640 12.8 14.0 1.2 2.4 236.5 0.9 1.1 0.3
IVS16-2A>G
Sequence Walker  
t48615107c 48615107 -1 48615106 -6.6 0.9 7.6 1.9 192.8 -3.4 -1.7 1.7
IVS16-2A>G
Sequence Walker  
t48615107c 48615099 7 48615106 -0.1 0.2 0.3 1.2 116.4 -2.0 -1.9 0.1
IVS17+1G>C
Sequence Walker  
c48615006g 48614988 18 48615006 2.6 3.5 0.8 1.8 179.6 -1.4 -1.2 0.2
IVS17+1G>C
Sequence Walker  
c48615006g 48615002 4 48615006 -2.0 0.5 2.5 1.4 140.9 -2.4 -1.8 0.6
IVS18+1G>A
Sequence Walker  
c48614873t 48614851 22 48614873 1.3 1.8 0.4 1.4 135.5 -1.6 -1.5 0.1
IVS18-1G>A
Sequence Walker  
c48614771t 48614773 -2 48614771 2.2 2.2 0.0 1.0 103.1 -1.5 -1.5 0.0
IVS18-1G>A
Sequence Walker  
c48614771t 48614752 19 48614771 0.0 0.2 0.2 1.1 113.7 -1.9 -1.9 0.0
IVS18-1G>A
Sequence Walker  
c48614771t 48614770 1 48614771 -2.6 5.6 8.2 47.7 4770.3 -2.5 -0.7 1.8
IVS20-2A>G
Sequence Walker  
t48614270c 48614270 -1 48614269 -2.5 5.1 7.6 33.3 3333.6 -2.5 -0.8 1.7
IVS5-1G>A
Sequence Walker  
c48617945t 48617943 2 48617945 -0.2 1.5 1.7 2.9 292.8 -2.0 -1.6 0.4
IVS5-2A>G
Sequence Walker  
t48617946c 48617930 15 48617945 7.4 7.4 0.0 1.0 103.1 -0.3 -0.3 0.0
IVS5-2A>G
Sequence Walker  
t48617946c 48617946 -1 48617945 -3.1 4.5 7.6 22.2 2215.5 -2.6 -1.0 1.7
IVS8+1G>C
Sequence Walker  
c48617388g 48617370 18 48617388 5.6 6.4 0.8 1.8 179.6 -0.7 -0.5 0.2
IVS9-1G>T
Sequence Walker  
c48616674a 48616673 1 48616674 2.7 3.4 0.7 1.7 166.6 -1.4 -1.2 0.2
IVS9-1G>T
Sequence Walker  
c48616674a 48616667 7 48616674 0.2 2.1 2.0 3.9 391.8 -1.9 -1.5 0.4
IVS9-1G>T
Sequence Walker  
c48616674a 48616672 2 48616674 -0.3 4.0 4.3 16.2 1620.7 -2.0 -1.1 0.9
c.1299+1G>C
Sequence Walker  
c48614873g 48614858 15 48614873 0.1 1.2 1.1 2.2 216.5 -1.9 -1.7 0.2
c.1299+1G>C
Sequence Walker  
c48614873g 48614851 22 48614873 1.3 2.3 0.9 1.9 192.0 -1.6 -1.4 0.2