Gene: COL1A1
mRNA Accession: Z74615
Mutation:COL1A1.txt
Chromosome: chr 17

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
IVS22-1G>T
Sequence Walker  
c48613888a 48613888 0 48613888 7.0 -1.8 -8.7 -127.8 NA -0.4 -2.3 -1.9
IVS25-1G>A
Sequence Walker
c48612488t 48612488 0 48612488 13.8 6.3 -7.6 -191.1 0.5 1.1 -0.6 -1.7
IVS26-2A>C
Sequence Walker
t48612292g 48612294 -3 48612291 4.5 4.1 -0.5 -1.4 72.3 -0.9 -1.1 -0.1
IVS26-2A>C
Sequence Walker
t48612292g 48612291 0 48612291 15.4 8.0 -7.4 -171.7 0.5 1.4 -0.2 -1.6
IVS27-1G>C
Sequence Walker
c48612134g 48612134 0 48612134 8.8 1.6 -7.3 -156.4 0.6 -0.0 -1.6 -1.6
IVS47-3C>G
Sequence Walker
g48606365c 48606363 0 48606363 15.2 9.3 -6.0 -62.7 1.5 1.4 0.1 -1.3
IVS47-3C>G
Sequence Walker
g48606365c 48606362 1 48606363 0.5 0.3 -0.2 -1.2 86.5 -1.8 -1.9 -0.0
IVS12+1G>A
Sequence Walker
c48616056t 48616057 -1 48616056 1.3 0.4 -1.0 -1.9 51.5 -1.6 -1.9 -0.2
IVS13-10T>A
Sequence Walker
a48615817t 48615808 0 48615808 8.4 5.8 -2.6 -6.1 16.3 -0.1 -0.7 -0.6
IVS15-33--44delCTGCCATCTCTT
Sequence Walker
d48615661,48615672 48615643 -3 48615640 3.1 2.4 -0.7 -1.7 59.7 -1.3 -1.4 -0.2
IVS16-2A>G
Sequence Walker
t48615107c 48615106 0 48615106 11.4 3.3 -8.2 -286.2 0.3 0.6 -1.2 -1.8
IVS18+1G>A
Sequence Walker  
c48614873t 48614858 15 48614873 0.1 -0.2 -0.2 -1.0 NA -1.9 -2.0 -0.0
IVS18-1G>A
Sequence Walker
c48614771t 48614771 0 48614771 10.4 2.8 -7.6 -191.1 0.5 0.3 -1.3 -1.7
IVS20-2A>G
Sequence Walker
t48614270c 48614269 0 48614269 12.7 4.5 -8.2 -286.2 0.3 0.8 -0.9 -1.8
IVS20-2A>G
Sequence Walker
t48614270c 48614250 19 48614269 3.5 3.2 -0.3 -1.2 81.8 -1.2 -1.2 -0.1
IVS5-1G>A
Sequence Walker
c48617945t 48617945 0 48617945 10.9 3.3 -7.6 -191.1 0.5 0.4 -1.2 -1.7
IVS5-1G>A
Sequence Walker
c48617945t 48617930 15 48617945 7.4 7.1 -0.2 -1.2 85.8 -0.3 -0.4 -0.0
IVS5-2A>G
Sequence Walker
t48617946c 48617945 0 48617945 10.9 2.7 -8.2 -286.2 0.3 0.4 -1.3 -1.8
IVS9-1G>T
Sequence Walker
c48616674a 48616674 0 48616674 14.2 5.5 -8.7 -430.0 0.2 1.2 -0.7 -1.9
c.333G>T;.c333+1G>C
Sequence Walker
c48619277a.c48619192g 48619193 -1 48619192 4.9 3.0 -1.9 -3.8 26.5 -0.9 -1.3 -0.4