Gene: BRCA2
mRNA Accession: U43746
Mutation:BRCA2.txt
Chromosome: chr 13

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1742T>C
Sequence Walker  
t31843765c 31843731 -430 31844161 0.2 0.2 0.0 1.0 100 -2.4 -2.4 0.0
1742T>C
Sequence Walker  
t31843765c 31843750 -411 31844161 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
1742T>C
Sequence Walker  
t31843765c 31843803 -358 31844161 1.3 1.3 0.0 1.0 100 -2.1 -2.1 0.0
6893A>G
Sequence Walker  
a31851793g 31851759 -211 31851970 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
5416A>T
Sequence Walker  
a31850316t 31850273 -1697 31851970 1.0 1.0 0.0 1.0 100 -2.1 -2.1 0.0
5416A>T
Sequence Walker  
a31850316t 31850346 -1624 31851970 0.0 0.0 0.0 1.0 100 -2.4 -2.4 0.0
5416A>T
Sequence Walker  
a31850316t 31850350 -1620 31851970 2.9 2.9 0.0 1.0 100 -1.5 -1.5 0.0
5868T>G
Sequence Walker  
t31850768g 31850740 -1230 31851970 0.8 0.8 0.0 1.0 100 -2.2 -2.2 0.0
5868T>G
Sequence Walker  
t31850768g 31850745 -1225 31851970 5.6 5.6 0.0 1.0 100 -0.7 -0.7 0.0
5868T>G
Sequence Walker  
t31850768g 31850803 -1167 31851970 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
4035T>C
Sequence Walker  
t31848935c 31848891 1854 31847037 4.8 4.8 0.0 1.0 100 -1.0 -1.0 0.0
4035T>C
Sequence Walker  
t31848935c 31848916 1879 31847037 6.6 6.6 0.0 1.0 100 -0.4 -0.4 0.0
4035T>C
Sequence Walker  
t31848935c 31848975 1938 31847037 7.6 7.6 0.0 1.0 100 -0.1 -0.1 0.0
4035T>C
Sequence Walker  
t31848935c 31848979 1942 31847037 2.6 2.6 0.0 1.0 100 -1.7 -1.7 0.0
6631A>C
Sequence Walker  
a31851531c 31851480 -490 31851970 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
6631A>C
Sequence Walker  
a31851531c 31851508 -462 31851970 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
6631A>C
Sequence Walker  
a31851531c 31851547 -423 31851970 5.5 5.5 0.0 1.0 100 -0.8 -0.8 0.0
9179C>G
Sequence Walker  
c31890286g 31890240 -49 31890289 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
9179C>G
Sequence Walker  
c31890286g 31890249 -40 31890289 1.3 1.3 0.0 1.0 100 -2.0 -2.0 0.0
9179C>G
Sequence Walker  
c31890286g 31890258 -31 31890289 5.2 5.2 0.0 1.0 100 -0.9 -0.9 0.0
9179C>G
Sequence Walker  
c31890286g 31890293 4 31890289 5.0 5.0 0.0 1.0 100 -0.9 -0.9 0.0
9179C>G
Sequence Walker  
c31890286g 31890297 8 31890289 4.7 4.7 0.0 1.0 100 -1.0 -1.0 0.0
5972C>T
Sequence Walker  
c31850872t 31850886 -1084 31851970 1.5 1.5 0.0 1.0 100 -2.0 -2.0 0.0
5972C>T
Sequence Walker  
c31850872t 31850905 -1065 31851970 2.1 2.1 0.0 1.0 100 -1.8 -1.8 0.0
6174delT
Sequence Walker  
d31851074,31851074 31851029 -941 31851970 3.1 3.1 0.0 1.0 100 -1.5 -1.5 0.0
6174delT
Sequence Walker  
d31851074,31851074 31851052 -918 31851970 2.2 2.2 0.0 1.0 100 -1.8 -1.8 0.0
6174delT
Sequence Walker  
d31851074,31851074 31851090 -880 31851970 4.5 4.5 0.0 1.0 100 -1.1 -1.1 0.0
5909insA
Sequence Walker  
i31850809,31850810a 31850803 -1167 31851970 1.7 1.7 0.0 1.0 100 -1.9 -1.9 0.0
6630delTAACT
Sequence Walker  
d31851526,31851530 31851480 -490 31851970 0.1 0.1 0.0 1.0 100 -2.4 -2.4 0.0
6630delTAACT
Sequence Walker  
d31851526,31851530 31851508 -462 31851970 1.8 1.8 0.0 1.0 100 -1.9 -1.9 0.0
6630delTAACT
Sequence Walker  
d31851526,31851530 31851547 -423 31851970 5.5 5.5 0.0 1.0 100 -0.8 -0.8 0.0