Gene: BRCA2
mRNA Accession: U43746
Mutation:BRCA2.txt
Chromosome: chr 13

Sequence Walker  


Decrease of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
9179C>G
Sequence Walker
c31890286g 31890289 0 31890289 12.7 11.6 -1.2 -2.2 44.7 1.4 1.1 -0.4
5972C>T
Sequence Walker
c31850872t 31850866 -1104 31851970 0.9 0.6 -0.3 -1.2 80.2 -2.1 -2.2 -0.1
6174delT
Sequence Walker  
d31851074,31851074 31851069 -901 31851970 0.4 -0.8 -1.2 -1.3 NA -2.3 -2.7 -0.4
6174delT
Sequence Walker  
d31851074,31851074 31851073 -897 31851970 1.6 -4.0 -5.6 -3.0 NA -1.9 -3.7 -1.7