Gene: BRCA2
mRNA Accession: U43746
Mutation:BRCA2.txt
Chromosome: chr 13

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1742T>C
Sequence Walker  
t31843765c 31843748 -413 31844161 11.4 11.4 0.0 1.0 100 0.5 0.5 0.0
1742T>C
Sequence Walker  
t31843765c 31843749 -412 31844161 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
1742T>C
Sequence Walker  
t31843765c 31843815 -346 31844161 4.4 4.4 0.0 1.0 100 -1.0 -1.0 0.0
6893A>G
Sequence Walker  
a31851793g 31851778 -192 31851970 0.7 0.7 0.0 1.0 100 -1.8 -1.8 0.0
6893A>G
Sequence Walker  
a31851793g 31851780 -190 31851970 4.6 4.6 0.0 1.0 100 -0.9 -0.9 0.0
6893A>G
Sequence Walker  
a31851793g 31851786 -184 31851970 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
5416A>T
Sequence Walker  
a31850316t 31850356 -1614 31851970 0.2 0.2 0.0 1.0 100 -1.9 -1.9 0.0
4035T>C
Sequence Walker  
t31848935c 31848916 1879 31847037 0.9 0.9 0.0 1.0 100 -1.7 -1.7 0.0
6631A>C
Sequence Walker  
a31851531c 31851558 -412 31851970 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
9179C>G
Sequence Walker  
c31890286g 31890318 29 31890289 6.0 6.0 0.0 1.0 100 -0.6 -0.6 0.0
5972C>T
Sequence Walker  
c31850872t 31850853 -1117 31851970 4.8 4.8 0.0 1.0 100 -0.9 -0.9 0.0
5972C>T
Sequence Walker  
c31850872t 31850903 -1067 31851970 4.8 4.8 0.0 1.0 100 -0.9 -0.9 0.0
6174delT
Sequence Walker  
d31851074,31851074 31851064 -906 31851970 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
6174delT
Sequence Walker  
d31851074,31851074 31851069 -901 31851970 2.4 2.4 0.0 1.0 100 -1.4 -1.4 0.0
5909insA
Sequence Walker  
i31850809,31850810a 31850853 -1117 31851970 4.8 4.8 0.0 1.0 100 -0.9 -0.9 0.0
6630delTAACT
Sequence Walker  
d31851526,31851530 31851558 -412 31851970 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0