Gene: SPAST
mRNA Accession: AJ246001
Mutation:SPAST.txt
Chromosome: chr 2

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
334G>T
Sequence Walker  
g32246944t 32246932 -94 32247026 2.5 2.5 0.0 1.0 100 -1.7 -1.7 0.0
334G>T
Sequence Walker  
g32246944t 32246985 -41 32247026 0.6 0.6 0.0 1.0 100 -2.3 -2.3 0.0
1005-1G>T
Sequence Walker  
g32298897t 32298930 33 32298897 1.1 1.1 0.0 1.0 100 -2.1 -2.1 0.0
1134_1135delGT
Sequence Walker  
d32309762,32309763 32309712 -14 32309726 2.9 2.9 0.0 1.0 100 -1.6 -1.6 0.0
1134_1135delGT
Sequence Walker  
d32309762,32309763 32309788 62 32309726 0.4 0.4 0.0 1.0 100 -2.3 -2.3 0.0
1134_1135delGT
Sequence Walker  
d32309762,32309763 32309802 76 32309726 9.8 9.8 0.0 1.0 100 0.5 0.5 0.0
1508G>T
Sequence Walker  
g32324697t 32324662 -20 32324682 1.3 1.3 0.0 1.0 100 -2.0 -2.0 0.0
1508G>T
Sequence Walker  
g32324697t 32324726 44 32324682 8.5 8.5 0.0 1.0 100 0.1 0.1 0.0
1508G>T
Sequence Walker  
g32324697t 32324730 48 32324682 1.2 1.2 0.0 1.0 100 -2.1 -2.1 0.0
1577_1580delGAAG
Sequence Walker  
d32326155,32326158 32326146 32 32326114 2.9 2.9 0.0 1.0 100 -1.6 -1.6 0.0
1577_1580delGAAG
Sequence Walker  
d32326155,32326158 32326195 81 32326114 10.7 10.7 0.0 1.0 100 0.8 0.8 0.0
1577_1580delGAAG
Sequence Walker  
d32326155,32326158 32326199 85 32326114 1.3 1.3 0.0 1.0 100 -2.0 -2.0 0.0
1720delG
Sequence Walker  
d32330029,32330029 32330014 -24 32330038 7.6 7.6 0.0 1.0 100 -0.1 -0.1 0.0
1720delG
Sequence Walker  
d32330029,32330029 32330033 -5 32330038 5.5 5.5 0.0 1.0 100 -0.8 -0.8 0.0
1720delG
Sequence Walker  
d32330029,32330029 32330038 0 32330038 3.2 3.2 0.0 1.0 100 -1.5 -1.5 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330014 -24 32330038 7.6 7.6 0.0 1.0 100 -0.1 -0.1 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330079 41 32330038 5.3 5.3 0.0 1.0 100 -0.8 -0.8 0.0