Gene: SPAST
mRNA Accession: AJ246001
Mutation:SPAST.txt
Chromosome: chr 2

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site
Closest
Natural Site
Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
334G>T
Sequence Walker  
g32246944t 32246976 -50 32247026 3.0 3.0 0.0 1.0 100 -1.3 -1.3 0.0
1005-1G>T
Sequence Walker  
g32298897t 32298872 -25 32298897 5.8 5.8 0.0 1.0 100 -0.7 -0.7 0.0
1134_1135delGT
Sequence Walker  
d32309762,32309763 32309736 10 32309726 9.5 9.5 0.0 1.0 100 0.1 0.1 0.0
1134_1135delGT
Sequence Walker  
d32309762,32309763 32309755 29 32309726 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
1508G>T
Sequence Walker  
g32324697t 32324682 0 32324682 9.0 9.0 0.0 1.0 100 0.0 0.0 0.0
1720delG
Sequence Walker  
d32330029,32330029 32330075 37 32330038 2.9 2.9 0.0 1.0 100 -1.3 -1.3 0.0
1720delG
Sequence Walker  
d32330029,32330029 32330077 39 32330038 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
1720delG
Sequence Walker  
d32330029,32330029 32330079 41 32330038 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330075 37 32330038 2.9 2.9 0.0 1.0 100 -1.3 -1.3 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330077 39 32330038 1.7 1.7 0.0 1.0 100 -1.6 -1.6 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330079 41 32330038 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330082 44 32330038 4.0 4.0 0.0 1.0 100 -1.1 -1.1 0.0
1728+2T>A
Sequence Walker  
t32330039a 32330083 45 32330038 4.6 4.6 0.0 1.0 100 -0.9 -0.9 0.0